KEGG   Homo sapiens (human): 7376
Entry
7376              CDS       T01001                                 
Symbol
NR1H2, LXR-b, LXRB, NER, NER-I, RIP15, UNR
Name
(RefSeq) nuclear receptor subfamily 1 group H member 2
  KO
K08535  liver X receptor beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04931  Insulin resistance
Drug target
Abequolixron (DG03218): D12298 D12299
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    7376 (NR1H2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    7376 (NR1H2)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    7376 (NR1H2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    7376 (NR1H2)
Nuclear receptors [BR:hsa03310]
 1. Thyroid hormone like
  1H. Liver X receptor like receptor
   7376 (NR1H2)
SSDB
Motif
Pfam: Hormone_recep zf-C4 PBP_N
Other DBs
NCBI-GeneID: 7376
NCBI-ProteinID: NP_009052
OMIM: 600380
HGNC: 7965
Ensembl: ENSG00000131408
Pharos: P55055(Tchem)
UniProt: P55055 F1D8P7
Structure
Position
19:50376457..50383388
AA seq 460 aa
MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgtcctctcctaccacgagttccctggatacccccctgcctggaaatggcccccctcag
cctggcgccccttcttcttcacccactgtaaaggaggagggtccggagccgtggcccggg
ggtccggaccctgatgtcccaggcactgatgaggccagctcagcctgcagcacagactgg
gtcatcccagatcccgaagaggaaccagagcgcaagcgaaagaagggcccagccccgaag
atgctgggccacgagctttgccgtgtctgtggggacaaggcctccggcttccactacaac
gtgctcagctgcgaaggctgcaagggcttcttccggcgcagtgtggtccgtggtggggcc
aggcgctatgcctgccggggtggcggaacctgccagatggacgctttcatgcggcgcaag
tgccagcagtgccggctgcgcaagtgcaaggaggcagggatgagggagcagtgcgtcctt
tctgaagaacagatccggaagaagaagattcggaaacagcagcaggagtcacagtcacag
tcgcagtcacctgtggggccgcagggcagcagcagctcagcctctgggcctggggcttcc
cctggtggatctgaggcaggcagccagggctccggggaaggcgagggtgtccagctaaca
gcggctcaagaactaatgatccagcagttggtggcggcccaactgcagtgcaacaaacgc
tccttctccgaccagcccaaagtcacgccctggcccctgggcgcagacccccagtcccga
gatgcccgccagcaacgctttgcccacttcacggagctggccatcatctcagtccaggag
atcgtggacttcgctaagcaagtgcctggtttcctgcagctgggccgggaggaccagatc
gccctcctgaaggcatccactatcgagatcatgctgctagagacagccaggcgctacaac
cacgagacagagtgtatcaccttcttgaaggacttcacctacagcaaggacgacttccac
cgtgcaggcctgcaggtggagttcatcaaccccatcttcgagttctcgcgggccatgcgg
cggctgggcctggacgacgctgagtacgccctgctcatcgccatcaacatcttctcggcc
gaccggcccaacgtgcaggagccgggccgcgtggaggcgttgcagcagccctacgtggag
gcgctgctgtcctacacgcgcatcaagaggccgcaggaccagctgcgcttcccgcgcatg
ctcatgaagctggtgagcctgcgcacgctgagctctgtgcactcggagcaggtcttcgcc
ttgcggctccaggacaagaagctgccgcctctgctgtcggagatctgggacgtccacgag
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
   PHAROS (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (36)   
   RefSeq(nuc) (2)   
   GenBank (17)   
   EMBL (17)   
3D Structure (25)   
   PDB (25)   
Protein domain (3)   
   Pfam (3)   
All databases (102)   

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