KEGG   Homo sapiens (human): 7376
Entry
7376              CDS       T01001                                 
Symbol
NR1H2, LXR-b, LXRB, NER, NER-I, RIP15, UNR
Name
(RefSeq) nuclear receptor subfamily 1 group H member 2
  KO
K08535  liver X receptor beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04148  Efferocytosis
hsa04931  Insulin resistance
Drug target
Abequolixron (DG03218): D12298 D12299
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    7376 (NR1H2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    7376 (NR1H2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    7376 (NR1H2)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    7376 (NR1H2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    7376 (NR1H2)
Nuclear receptors [BR:hsa03310]
 1. Thyroid hormone like
  1H. Liver X receptor like receptor
   7376 (NR1H2)
SSDB
Motif
Pfam: Hormone_recep zf-C4 PBP_N
Other DBs
NCBI-GeneID: 7376
NCBI-ProteinID: NP_009052
OMIM: 600380
HGNC: 7965
Ensembl: ENSG00000131408
UniProt: P55055 F1D8P7
Structure
Position
19:50376457..50383388
AA seq 460 aa
MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgtcctctcctaccacgagttccctggatacccccctgcctggaaatggcccccctcag
cctggcgccccttcttcttcacccactgtaaaggaggagggtccggagccgtggcccggg
ggtccggaccctgatgtcccaggcactgatgaggccagctcagcctgcagcacagactgg
gtcatcccagatcccgaagaggaaccagagcgcaagcgaaagaagggcccagccccgaag
atgctgggccacgagctttgccgtgtctgtggggacaaggcctccggcttccactacaac
gtgctcagctgcgaaggctgcaagggcttcttccggcgcagtgtggtccgtggtggggcc
aggcgctatgcctgccggggtggcggaacctgccagatggacgctttcatgcggcgcaag
tgccagcagtgccggctgcgcaagtgcaaggaggcagggatgagggagcagtgcgtcctt
tctgaagaacagatccggaagaagaagattcggaaacagcagcaggagtcacagtcacag
tcgcagtcacctgtggggccgcagggcagcagcagctcagcctctgggcctggggcttcc
cctggtggatctgaggcaggcagccagggctccggggaaggcgagggtgtccagctaaca
gcggctcaagaactaatgatccagcagttggtggcggcccaactgcagtgcaacaaacgc
tccttctccgaccagcccaaagtcacgccctggcccctgggcgcagacccccagtcccga
gatgcccgccagcaacgctttgcccacttcacggagctggccatcatctcagtccaggag
atcgtggacttcgctaagcaagtgcctggtttcctgcagctgggccgggaggaccagatc
gccctcctgaaggcatccactatcgagatcatgctgctagagacagccaggcgctacaac
cacgagacagagtgtatcaccttcttgaaggacttcacctacagcaaggacgacttccac
cgtgcaggcctgcaggtggagttcatcaaccccatcttcgagttctcgcgggccatgcgg
cggctgggcctggacgacgctgagtacgccctgctcatcgccatcaacatcttctcggcc
gaccggcccaacgtgcaggagccgggccgcgtggaggcgttgcagcagccctacgtggag
gcgctgctgtcctacacgcgcatcaagaggccgcaggaccagctgcgcttcccgcgcatg
ctcatgaagctggtgagcctgcgcacgctgagctctgtgcactcggagcaggtcttcgcc
ttgcggctccaggacaagaagctgccgcctctgctgtcggagatctgggacgtccacgag
tga

  All links  
Disease (1)   
   OMIM (1)   
Gene (23)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (36)   
   RefSeq(nuc) (2)   
   GenBank (17)   
   EMBL (17)   
3D Structure (25)   
   PDB (25)   
Protein domain (3)   
   Pfam (3)   
All databases (93)   

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