KEGG   Homo sapiens (human): 7389
Entry
7389              CDS       T01001                                 
Symbol
UROD, PCT, UPD
Name
(RefSeq) uroporphyrinogen decarboxylase
  KO
K01599  uroporphyrinogen decarboxylase [EC:4.1.1.37]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00860  Porphyrin metabolism
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
Module
hsa_M00868  Heme biosynthesis, animals and fungi, glycine => heme
Network
nt06011  Heme biosynthesis
  Element
N00601  Heme biosynthesis
Disease
H00201  Erythropoietic porphyria
H00202  Hepatic porphyria
H01763  Porphyria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    7389 (UROD)
Enzymes [BR:hsa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.37  uroporphyrinogen decarboxylase
     7389 (UROD)
SSDB
Motif
Pfam: URO-D
Other DBs
NCBI-GeneID: 7389
NCBI-ProteinID: NP_000365
OMIM: 613521
HGNC: 12591
Ensembl: ENSG00000126088
UniProt: P06132
Structure
Position
1:45012254..45015575
AA seq 367 aa
MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCR
SPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLER
LRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRW
LYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDV
AKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVT
LQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKH
SRLLRQN
NT seq 1104 nt   +upstreamnt  +downstreamnt
atggaagcgaatgggttgggacctcagggttttccggagctgaagaatgacacattcctg
cgagcagcctggggagaggaaacagactacactcccgtttggtgcatgcgccaggcaggc
cgttacttaccagagtttagggaaacccgggctgcccaggactttttcagcacgtgtcgc
tctcctgaggcctgctgtgaactgactctgcagccactgcgtcgcttccctctggatgct
gccatcattttctccgacatccttgttgtaccccaggcactgggcatggaggtgaccatg
gtacctggcaaaggacccagcttcccagagccattaagagaagagcaggacctagaacgc
ctacgggatccagaagtggtagcctctgagctaggctatgtgttccaagccatcaccctt
acccgacaacgactggctggacgtgtgccgctgattggctttgctggtgccccatggacc
ctgatgacatacatggttgagggtggtggctcaagcaccatggctcaggccaagcgctgg
ctctatcagagacctcaggctagtcaccagctgcttcgcatcctcactgatgctctggtc
ccatatctggtaggacaagtggtggctggtgcccaggcattgcagctgtttgagtcccat
gcagggcatcttggcccacagctcttcaacaagtttgcactgccttacatccgtgatgtg
gccaagcaagtgaaggccaggttgcgggaggcaggcctggcaccagtgcccatgatcatc
tttgctaaggatgggcattttgccctggaggagctggcccaagctggctatgaggtggtt
gggcttgactggacagtggccccaaagaaagcccgggagtgtgtggggaagacggtgaca
ttgcagggcaacctggacccctgtgccttgtatgcatctgaggaggagatcgggcagttg
gtgaagcagatgctggatgactttggaccacatcgctacattgccaacctgggccatggg
ctttatcctgacatggacccagaacatgtgggcgcctttgtggatgctgtgcataaacac
tcacgtctgcttcgacagaactga

  All links  
Disease (2)   
   OMIM (2)   
Gene (17)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (81)   
   RefSeq(nuc) (7)   
   GenBank (37)   
   EMBL (37)   
3D Structure (19)   
   PDB (19)   
Protein domain (1)   
   Pfam (1)   
All databases (126)   

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