KEGG   Homo sapiens (human): 7398
Entry
7398              CDS       T01001                                 
Symbol
USP1, UBP
Name
(RefSeq) ubiquitin specific peptidase 1
  KO
K11832  ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    7398 (USP1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    7398 (USP1)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    7398 (USP1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    7398 (USP1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     7398 (USP1)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   7398 (USP1)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    7398 (USP1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   FA (Fanconi anemia) pathway
    Other FA pathway factors
     7398 (USP1)
SSDB
Motif
Pfam: UCH UCH_1
Other DBs
NCBI-GeneID: 7398
NCBI-ProteinID: NP_001017415
OMIM: 603478
HGNC: 12607
Ensembl: ENSG00000162607
UniProt: O94782
Structure
Position
1:62436395..62451804
AA seq 785 aa
MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV
VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK
EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR
LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK
EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT
RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK
ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ
IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT
EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL
EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV
TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK
KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD
QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL
FYKKL
NT seq 2358 nt   +upstreamnt  +downstreamnt
atgcctggtgtcatacctagtgaaagtaatggactttcaagaggtagcccttcaaagaaa
aacagactttccttaaagttttttcagaaaaaggaaactaagagagctttggatttcaca
gattctcaagaaaatgaagaaaaagcttctgaatatagagcatctgaaattgatcaagtt
gttcctgcagcacagtcttcacctataaactgtgagaagagagaaaacttgttaccattt
gtgggactgaataatctcggcaatacttgctatcttaatagtatacttcaggtattatat
ttttgtcccggttttaaatctggagtaaagcacttatttaatattatttcaaggaagaaa
gaagctctaaaggatgaagccaatcaaaaagacaagggaaattgcaaagaagattctttg
gcaagttatgaattgatatgcagtttacagtccttaatcatttcggttgaacagctccag
gctagttttctcttaaatccagagaaatatactgatgaacttgccactcagccaaggcga
ctgcttaacacactgagggaactcaaccctatgtatgaaggatatctacagcatgatgca
caggaagtattacaatgtattttgggaaacattcaagaaacatgccaactcctaaaaaaa
gaagaagtaaaaaatgtggcagaattacctactaaggtagaagaaatacctcatccgaaa
gaggaaatgaatggtattaacagcatagagatggacagtatgaggcattctgaagacttt
aaagagaaactcccaaaaggaaatgggaaaagaaaaagtgacactgaatttggtaacatg
aagaaaaaagttaaattatccaaggaacaccagtcattggaagagaaccagagacaaact
agatcaaaaagaaaagctacaagtgatacattagagagtcctcctaaaataattcccaag
tatatttctgaaaatgagagtccaagaccctcacaaaagaaatcaagagttaaaataaat
tggttaaagtctgcaactaagcaacccagcattctttctaaattttgtagtctgggaaaa
ataacaacaaaccaaggagtcaaaggacaatctaaagaaaatgaatgtgatcctgaagag
gacttggggaagtgtgaaagtgataacacaactaatggttgtggacttgaatctccagga
aatactgttacacctgtaaatgttaatgaagttaaacccataaacaaaggtgaagaacaa
attggttttgagctagtggagaaattatttcaaggtcagctggtattaaggacgcgttgc
ttggaatgtgaaagtttaacagaaagaagagaagattttcaagacatcagtgtgccagta
caagaagatgagctttccaaagtagaggagagttctgaaatttctccagagccaaaaaca
gaaatgaagaccctgagatgggcaatttcacaatttgcttcagtagaaaggattgtagga
gaagataaatatttctgtgaaaactgccatcattatactgaagctgaacgaagtcttttg
tttgacaaaatgcctgaagttataactattcatttgaagtgctttgctgctagtggtttg
gagtttgattgttatggtggtggactttccaagatcaacactcctttattgacacctctt
aaattgtcactagaagaatggagcacaaagccaactaacgacagctatggattatttgcg
gttgtgatgcatagtggcattacaattagtagtgggcattacactgcttctgttaaagtc
actgaccttaacagtttagaactagataaaggaaattttgtggttgaccaaatgtgtgaa
ataggtaagccagaaccattgaatgaggaggaagcaaggggtgtggttgagaattataat
gatgaagaagtgtcaattagagttggtggaaatacacagccaagtaaagttttgaacaaa
aaaaatgtagaagctattggacttcttggaggacaaaagagcaaagcagattatgagcta
tacaacaaagcctctaatcctgataaggttgctagtacagcgtttgctgaaaatagaaat
tctgagactagtgatactactgggacccatgaatctgatagaaacaaggaatccagtgac
caaacaggcattaatattagtggatttgagaacaaaatttcatacgtagtgcaaagctta
aaggagtatgaggggaagtggttgctttttgatgattctgaagtcaaagttactgaagag
aaggactttctgaattctctttccccttctacatctcctacttctactccttacttgcta
ttttataagaaattatag

  All links  
Disease (1)   
   OMIM (1)   
Gene (17)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (37)   
   RefSeq(nuc) (3)   
   GenBank (17)   
   EMBL (17)   
3D Structure (12)   
   PDB (12)   
Protein domain (2)   
   Pfam (2)   
All databases (74)   

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