| Entry |
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| Gene name |
VDAC1, PORIN, VDAC-1
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| Definition |
(RefSeq) voltage dependent anion channel 1
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| KO |
| K05862 | voltage-dependent anion channel protein 1 |
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| Organism |
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| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
| hsa05166 | Human T-cell leukemia virus 1 infection |
|
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| Network |
nt06131 Apoptosis (viruses and bacteria) nt06170 Influenza A virus (IAV) |
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| Element |
| N00745 | IAV PB1-F2 to intrinsic apoptotic pathway |
| N00950 | Escherichia/Salmonella/Shigella FimA to crosstalk between extrinsic and intrinsic apoptotic pathways |
|
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
7416 (VDAC1)
04022 cGMP-PKG signaling pathway
7416 (VDAC1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
7416 (VDAC1)
04218 Cellular senescence
7416 (VDAC1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
7416 (VDAC1)
09154 Digestive system
04979 Cholesterol metabolism
7416 (VDAC1)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
7416 (VDAC1)
05016 Huntington disease
7416 (VDAC1)
09171 Infectious disease: bacterial
05131 Shigellosis
7416 (VDAC1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
7416 (VDAC1)
05164 Influenza A
7416 (VDAC1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:hsa03029]
7416 (VDAC1)
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:hsa04040]
7416 (VDAC1)
Mitochondrial biogenesis [BR:hsa03029]
Mitochondrial protein import machinery
Outer membrane
Porin
7416 (VDAC1)
Ion channels [BR:hsa04040]
Chloride channels
Maxi chloride channel (VDAC)
7416 (VDAC1)
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
5q31.1
|
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| AA seq |
283 aa  
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET
KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR
EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL
HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS
SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA |
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| NT seq |
852 nt  +upstreamnt +downstreamnt
atggctgtgccacccacgtatgccgatcttggcaaatctgccagggatgtcttcaccaag
ggctatggatttggcttaataaagcttgatttgaaaacaaaatctgagaatggattggaa
tttacaagctcaggctcagccaacactgagaccaccaaagtgacgggcagtctggaaacc
aagtacagatggactgagtacggcctgacgtttacagagaaatggaataccgacaataca
ctaggcaccgagattactgtggaagatcagcttgcacgtggactgaagctgaccttcgat
tcatccttctcacctaacactgggaaaaaaaatgctaaaatcaagacagggtacaagcgg
gagcacattaacctgggctgcgacatggatttcgacattgctgggccttccatccggggt
gctctggtgctaggttacgagggctggctggccggctaccagatgaattttgagactgca
aaatcccgagtgacccagagcaactttgcagttggctacaagactgatgaattccagctt
cacactaatgtgaatgacgggacagagtttggcggctccatttaccagaaagtgaacaag
aagttggagaccgctgtcaatcttgcctggacagcaggaaacagtaacacgcgcttcgga
atagcagccaagtatcagattgaccctgacgcctgcttctcggctaaagtgaacaactcc
agcctgataggtttaggatacactcagactctaaagccaggtattaaactgacactgtca
gctcttctggatggcaagaacgtcaatgctggtggccacaagcttggtctaggactggaa
tttcaagcataa |
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