KEGG   Homo sapiens (human): 7442
Entry
7442              CDS       T01001                                 
Symbol
TRPV1, VR1
Name
(RefSeq) transient receptor potential cation channel subfamily V member 1
  KO
K05222  transient receptor potential cation channel subfamily V member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Drug target
Capsaicin: D00250<US>
Mavatrep: D10370
Motugivatrep: D12841
Nonivamide: D08282
Olvanil: D05249
Zucapsaicin: D06388
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    7442 (TRPV1)
 09150 Organismal Systems
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    7442 (TRPV1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7442 (TRPV1)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7442 (TRPV1)
SSDB
Motif
Pfam: Ank_2 Ank Ion_trans Ank_5 Ank_3
Other DBs
NCBI-GeneID: 7442
NCBI-ProteinID: NP_061197
OMIM: 602076
HGNC: 12716
Ensembl: ENSG00000196689
UniProt: Q8NER1
Structure
Position
17:complement(3565446..3609411)
AA seq 839 aa
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
NT seq 2520 nt   +upstreamnt  +downstreamnt
atgaagaaatggagcagcacagacttgggggcagctgcggacccactccaaaaggacacc
tgcccagaccccctggatggagaccctaactccaggccacctccagccaagccccagctc
tccacggccaagagccgcacccggctctttgggaagggtgactcggaggaggctttcccg
gtggattgccctcacgaggaaggtgagctggactcctgcccgaccatcacagtcagccct
gttatcaccatccagaggccaggagacggccccaccggtgccaggctgctgtcccaggac
tctgtcgccgccagcaccgagaagaccctcaggctctatgatcgcaggagtatctttgaa
gccgttgctcagaataactgccaggatctggagagcctgctgctcttcctgcagaagagc
aagaagcacctcacagacaacgagttcaaagaccctgagacagggaagacctgtctgctg
aaagccatgctcaacctgcacgacggacagaacaccaccatccccctgctcctggagatc
gcgcggcaaacggacagcctgaaggagcttgtcaacgccagctacacggacagctactac
aagggccagacagcactgcacatcgccatcgagagacgcaacatggccctggtgaccctc
ctggtggagaacggagcagacgtccaggctgcggcccatggggacttctttaagaaaacc
aaagggcggcctggattctacttcggtgaactgcccctgtccctggccgcgtgcaccaac
cagctgggcatcgtgaagttcctgctgcagaactcctggcagacggccgacatcagcgcc
agggactcggtgggcaacacggtgctgcacgccctggtggaggtggccgacaacacggcc
gacaacacgaagtttgtgacgagcatgtacaatgagattctgatgctgggggccaaactg
cacccgacgctgaagctggaggagctcaccaacaagaagggaatgacgccgctggctctg
gcagctgggaccgggaagatcggggtcttggcctatattctccagcgggagatccaggag
cccgagtgcaggcacctgtccaggaagttcaccgagtgggcctacgggcccgtgcactcc
tcgctgtacgacctgtcctgcatcgacacctgcgagaagaactcggtgctggaggtgatc
gcctacagcagcagcgagacccctaatcgccacgacatgctcttggtggagccgctgaac
cgactcctgcaggacaagtgggacagattcgtcaagcgcatcttctacttcaacttcctg
gtctactgcctgtacatgatcatcttcaccatggctgcctactacaggcccgtggatggc
ttgcctccctttaagatggaaaaaactggagactatttccgagttactggagagatcctg
tctgtgttaggaggagtctacttctttttccgagggattcagtatttcctgcagaggcgg
ccgtcgatgaagaccctgtttgtggacagctacagtgagatgcttttctttctgcagtca
ctgttcatgctggccaccgtggtgctgtacttcagccacctcaaggagtatgtggcttcc
atggtattctccctggccttgggctggaccaacatgctctactacacccgcggtttccag
cagatgggcatctatgccgtcatgatagagaagatgatcctgagagacctgtgccgtttc
atgtttgtctacatcgtcttcttgttcgggttttccacagcggtggtgacgctgattgaa
gacgggaagaatgactccctgccgtctgagtccacgtcgcacaggtggcgggggcctgcc
tgcaggccccccgatagctcctacaacagcctgtactccacctgcctggagctgttcaag
ttcaccatcggcatgggcgacctggagttcactgagaactatgacttcaaggctgtcttc
atcatcctgctgctggcctatgtaattctcacctacatcctcctgctcaacatgctcatc
gccctcatgggtgagactgtcaacaagatcgcacaggagagcaagaacatctggaagctg
cagagagccatcaccatcctggacacggagaagagcttccttaagtgcatgaggaaggcc
ttccgctcaggcaagctgctgcaggtggggtacacacctgatggcaaggacgactaccgg
tggtgcttcagggtggacgaggtgaactggaccacctggaacaccaacgtgggcatcatc
aacgaagacccgggcaactgtgagggcgtcaagcgcaccctgagcttctccctgcggtca
agcagagtttcaggcagacactggaagaactttgccctggtcccccttttaagagaggca
agtgctcgagataggcagtctgctcagcccgaggaagtttatctgcgacagttttcaggg
tctctgaagccagaggacgctgaggtcttcaagagtcctgccgcttccggggagaagtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (20)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
3D Structure (7)   
   PDB (7)   
Protein domain (5)   
   Pfam (5)   
All databases (73)   

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