KEGG   Homo sapiens (human): 7512
Entry
7512              CDS       T01001                                 
Symbol
XPNPEP2, AEACEI, APP2
Name
(RefSeq) X-prolyl aminopeptidase 2
  KO
K14208  Xaa-Pro aminopeptidase 2 [EC:3.4.11.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    7512 (XPNPEP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    7512 (XPNPEP2)
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    7512 (XPNPEP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.11  Aminopeptidases
    3.4.11.9  Xaa-Pro aminopeptidase
     7512 (XPNPEP2)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M24
   7512 (XPNPEP2)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  7512 (XPNPEP2)
SSDB
Motif
Pfam: Creatinase_N_2 Peptidase_M24 Peptidase_M24_C Creatinase_N
Other DBs
NCBI-GeneID: 7512
NCBI-ProteinID: NP_003390
OMIM: 300145
HGNC: 12823
Ensembl: ENSG00000122121
UniProt: O43895
Position
X:129738979..129769536
AA seq 674 aa
MARAHWGCCPWLVLLCACAWGHTKPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQ
MQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVTMKKAAVWTDSRYWTQ
AERQMDCNWELHKEVGTTPIVTWLLTEIPAGGRVGFDPFLLSIDTWESYDLALQGSNRQL
VSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLS
ALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCV
QIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGIYEMIPKEKLVTDTYSPVMMTKAVKNSK
EQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGAEIVDKFRGEEQFSSGPSFETIS
ASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYT
RVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQ
SNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYPGSYLTFEVVSFVPYDRNL
IDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAPDTASWAS
VLVVSTLAILGWSV
NT seq 2025 nt   +upstreamnt  +downstreamnt
atggcccgggctcactggggctgctgcccctggctggtcctcctctgtgcttgtgcctgg
ggccacacaaagccagtggaccttggagggcaggatgtgagaaactgttccaccaacccc
ccttaccttccagttactgtggtcaataccacaatgtcactcacagccctccgccagcag
atgcagacccagaatctctcagcctacatcatcccaggcacagatgctcacatgaacgag
tacatcggccaacatgacgagaggcgtgcgtggattacaggctttacagggtctgcagga
actgcagtggtgactatgaagaaagcagctgtctggaccgacagtcgctactggactcag
gctgagcggcagatggactgcaactgggagctccataaggaagttggcaccactcctatt
gtcacctggctcctcaccgagattcctgctggagggcgtgtgggttttgaccccttcctc
ttgtccattgacacctgggagagttatgatctggccctccaaggctctaacagacagctg
gtgtccatcacaaccaatcttgtggacctggtatggggatcagagaggccaccggttcca
aatcaacccatttatgccctgcaggaggcattcacagggagcacttggcaggagaaagta
tctggcgtccgaagccagatgcagaagcatcaaaaggtcccgactgccgtccttctgtcg
gcgcttgaggagacggcctggctcttcaaccttcgagccagtgacatcccctataacccc
ttcttctattcctacacgctgctcacagactcttctattaggttgtttgcaaacaagagt
cgctttagctccgaaaccttgagctatctgaactccagttgcacaggccccatgtgtgtg
caaatcgaggattacagccaagttcgtgacagcatccaggcctactcattgggagatgtg
aggatctggattgggaccagctataccatgtatgggatctatgaaatgatacccaaggag
aaactcgtgacagacacctactccccagtgatgatgaccaaggcagtgaagaacagcaag
gagcaggccctcctcaaggccagccacgtgcgggacgctgtggctgtgatccggtacttg
gtctggctggagaagaacgtgcccaaaggcacagtggatgagttctcgggggcagagatc
gtggacaagttccgaggagaagaacagttctcctccggacccagttttgaaaccatctct
gctagtggtctgaatgctgccctggcccactacagcccgaccaaggagctgaaccgcaag
ctgtcctcagatgagatgtacctgctggactctggggggcagtactgggacgggaccaca
gacatcaccagaacagtccactggggcaccccctctgccttccagaaggaggcatacacc
cgtgtgctgataggaaatattgacctgtccaggctcatctttcccgctgctacatcaggg
cgaatggtggaggcctttgcccgcagagccttgtgggatgctggtctcaattatggtcat
gggacaggccacggcattggcaacttcctgtgtgtgcatgagtggccagtgggattccag
tccaacaacatcgctatggccaagggcatgttcacttccattgaacctggttactataag
gatggagaatttgggatccgtctcgaagatgtggctctcgtggtagaagcaaagaccaag
tacccagggagctacctgacctttgaagtggtatcatttgtgccctatgaccggaacctc
atcgatgtcagcctgctgtctcccgagcatctccagtacctgaatcgctactaccagacc
atccgggagaaggtgggtccagagctgcagaggcgccagctactagaggagttcgagtgg
cttcaacagcacacagagcccctggccgccagggccccagacaccgcctcctgggcctct
gtgttagtggtctccacccttgccatccttggctggagtgtctag

  All links  
Disease (2)   
   OMIM (2)   
Gene (12)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (42)   

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