KEGG   Homo sapiens (human): 7516
Entry
7516              CDS       T01001                                 
Symbol
XRCC2, FANCU, POF17, SPGF50
Name
(RefSeq) X-ray repair cross complementing 2
  KO
K10879  DNA-repair protein XRCC2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03440  Homologous recombination
Network
nt06506  Double-strand break repair
nt06508  Interstrand crosslink repair
  Element
N01452  Homologous recombination
N01539  RAD51 -dsDNA destabilization
Disease
H00238  Fanconi anemia
H00627  Premature ovarian failure
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    7516 (XRCC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    7516 (XRCC2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    RecA family proteins
     7516 (XRCC2)
SSDB
Motif
Pfam: Rad51 RecA AAA_25
Other DBs
NCBI-GeneID: 7516
NCBI-ProteinID: NP_005422
OMIM: 600375
HGNC: 12829
Ensembl: ENSG00000196584
UniProt: O43543 A0A384MEK2
Structure
Position
7:complement(152644776..152676141)
AA seq 280 aa
MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYH
LTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYC
SSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCL
EKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMF
FSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC
NT seq 843 nt   +upstreamnt  +downstreamnt
atgtgtagtgccttccatagggctgagtctgggaccgagctccttgcccgacttgaaggt
agaagttccttgaaagaaatagaaccaaatctgtttgctgatgaagattcacctgtgcat
ggtgatattcttgaatttcatggcccagaaggaacaggaaaaacagaaatgctttatcac
ctaacagcacgatgtatacttcccaaatcagaaggtggcctggaagtagaagtcttattt
attgatacagattaccactttgatatgctccggctagttacaattcttgagcacagacta
tcccaaagctctgaagaaataatcaaatactgcctgggaagattttttttggtgtactgc
agtagtagcacccacttacttcttacactttactcactagaaagtatgttttgtagtcac
ccatctctctgccttttgattttggatagcctgtcagctttttactggatagaccgcgtc
aatggaggagaaagtgtgaacttacaggagtctactctgaggaaatgttctcagtgctta
gagaagcttgtaaatgactatcgcctggttctttttgcaacgacacaaactataatgcag
aaagcctcgagctcatcagaagaaccttctcatgcctctcgacgactgtgtgatgtggac
atagactacagaccttatctctgtaaggcatggcagcaactggtgaagcacaggatgttt
ttctccaaacaagatgattctcaaagcagcaaccaattttcattagtttcacgttgttta
aaaagtaacagtttaaaaaaacatttttttattattggagaaagtggggttgaattttgt
tga

  All links  
Disease (4)   
   OMIM (4)   
Gene (11)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
3D Structure (4)   
   PDB (4)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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