KEGG   Homo sapiens (human): 7531Help
Entry
7531              CDS       T01001                                 

Gene name
YWHAE, 14-3-3E, HEL2, KCIP-1, MDCR, MDS
Definition
(RefSeq) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  KO
K06630  14-3-3 protein epsilon
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04390  Hippo signaling pathway
hsa04722  Neurotrophin signaling pathway
hsa05160  Hepatitis C
hsa05203  Viral carcinogenesis
Network
nt06110  MAPK signaling (virus)
nt06163  Hepatitis C virus (HCV)
  Element
N00518  HCV Core to ERK signaling pathway
Disease
H00268  Lissencephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    7531 (YWHAE)
   04151 PI3K-Akt signaling pathway
    7531 (YWHAE)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    7531 (YWHAE)
   04114 Oocyte meiosis
    7531 (YWHAE)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    7531 (YWHAE)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    7531 (YWHAE)
  09172 Infectious disease: viral
   05160 Hepatitis C
    7531 (YWHAE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    7531 (YWHAE)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7531 (YWHAE)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic Type
  Check point factors
   Other check point factors
    7531 (YWHAE)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   7531 (YWHAE)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 14-3-3 Orbi_VP5
Motif
Other DBs
NCBI-GeneID: 7531
NCBI-ProteinID: NP_006752
OMIM: 605066
HGNC: 12851
Ensembl: ENSG00000108953
Vega: OTTHUMG00000134316
Pharos: P62258(Tbio)
UniProt: P62258 V9HW98
Structure
PDB: 

Position
17p13.3
AA seq 255 aa AA seqDB search
MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW
RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF
YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF
YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGE
EQNKEALQDVEDENQ
NT seq 768 nt NT seq  +upstreamnt  +downstreamnt
atggatgatcgagaggatctggtgtaccaggcgaagctggccgagcaggctgagcgatac
gacgaaatggtggagtcaatgaagaaagtagcagggatggatgtggagctgacagttgaa
gaaagaaacctcctatctgttgcatataagaatgtgattggagctagaagagcctcctgg
agaataatcagcagcattgaacagaaagaagaaaacaagggaggagaagacaagctaaaa
atgattcgggaatatcggcaaatggttgagactgagctaaagttaatctgttgtgacatt
ctggatgtactggacaaacacctcattccagcagctaacactggcgagtccaaggttttc
tattataaaatgaaaggggactaccacaggtatctggcagaatttgccacaggaaacgac
aggaaggaggctgcggagaacagcctagtggcttataaagctgctagtgatattgcaatg
acagaacttccaccaacgcatcctattcgcttaggtcttgctctcaatttttccgtattc
tactacgaaattcttaattcccctgaccgtgcctgcaggttggcaaaagcagcttttgat
gatgcaattgcagaactggatacgctgagtgaagaaagctataaggactctacacttatc
atgcagttgttacgtgataatctgacactatggacttcagacatgcagggtgacggtgaa
gagcagaataaagaagcgctgcaggacgtggaagacgaaaatcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Network (1)   
   KEGG NETWORK (1)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (86)   
   KEGG ORTHOLOGY (1)   
   RefGene (57)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (21)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (44)   
   RefSeq(nuc) (4)   
   GenBank (20)   
   EMBL (20)   
Protein domain (2)   
   Pfam (2)   
All databases (152)   

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