KEGG   Homo sapiens (human): 762
Entry
762               CDS       T01001                                 
Symbol
CA4, CAIV, Car4, RP17
Name
(RefSeq) carbonic anhydrase 4
  KO
K18246  carbonic anhydrase 4 [EC:4.2.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00910  Nitrogen metabolism
hsa01100  Metabolic pathways
hsa04964  Proximal tubule bicarbonate reclamation
Disease
H00527  Retinitis pigmentosa
Drug target
Acetazolamide (DG01134): D00218<JP/US> D01196<JP/US>
Clofenamide: D01822
Diclofenamide: D00518<US>
Dorzolamide (DG01135): D00653<JP/US> D07871
Ethoxzolamide: D02441
Methazolamide: D00655<US>
Sezolamide hydrochloride: D03845
Topiramate: D00537<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00910 Nitrogen metabolism
    762 (CA4)
 09150 Organismal Systems
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    762 (CA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    762 (CA4)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    762 (CA4)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.1  carbonic anhydrase
     762 (CA4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   762 (CA4)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  762 (CA4)
SSDB
Motif
Pfam: Carb_anhydrase
Other DBs
NCBI-GeneID: 762
NCBI-ProteinID: NP_000708
OMIM: 114760
HGNC: 1375
Ensembl: ENSG00000167434
UniProt: P22748
Structure
Position
17:60149973..60179021
AA seq 312 aa
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
NT seq 939 nt   +upstreamnt  +downstreamnt
atgcggatgctgctggcgctcctggccctctccgcggcgcggccatcggccagtgcagag
tcacactggtgctacgaggttcaagccgagtcctccaactacccctgcttggtgccagtc
aagtggggtggaaactgccagaaggaccgccagtcccccatcaacatcgtcaccaccaag
gcaaaggtggacaaaaaactgggacgcttcttcttctctggctacgataagaagcaaacg
tggactgtccaaaataacgggcactcagtgatgatgttgctggagaacaaggccagcatt
tctggaggaggactgcctgccccataccaggccaaacagttgcacctgcactggtccgac
ttgccatataagggctcggagcacagcctcgatggggagcactttgccatggagatgcac
atagtacatgagaaagagaaggggacatcgaggaatgtgaaagaggcccaggaccctgaa
gacgaaattgcggtgctggcctttctggtggaggctggaacccaggtgaacgagggcttc
cagccactggtggaggcactgtctaatatccccaaacctgagatgagcactacgatggca
gagagcagcctgttggacctgctccccaaggaggagaaactgaggcactacttccgctac
ctgggctcactcaccacaccgacctgcgatgagaaggtcgtctggactgtgttccgggag
cccattcagcttcacagagaacagatcctggcattctctcagaagctgtactacgacaag
gaacagacagtgagcatgaaggacaatgtcaggcccctgcagcagctggggcagcgcacg
gtgataaagtccggggccccgggtcggccgctgccctgggccctgcctgccctgctgggc
cccatgctggcctgcctgctggccggcttcctgcgatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (30)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (21)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (38)   
   RefSeq(nuc) (20)   
   GenBank (9)   
   EMBL (9)   
3D Structure (10)   
   PDB (10)   
Protein domain (1)   
   Pfam (1)   
All databases (101)   

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