KEGG   Homo sapiens (human): 780Help
Entry
780               CDS       T01001                                 

Gene name
DDR1, CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
Definition
(RefSeq) discoidin domain receptor tyrosine kinase 1
  KO
K05124  discoidin domain receptor family member 1 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    780 (DDR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    780 (DDR1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     780 (DDR1)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  DDR family
   780 (DDR1)
CD molecules [BR:hsa04090]
 Proteins
  780 (DDR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Pkinase F5_F8_type_C Lamprin Haspin_kinase Kinase-like
Motif
Other DBs
NCBI-GeneID: 780
NCBI-ProteinID: NP_001284583
OMIM: 600408
HGNC: 2730
Ensembl: ENSG00000204580
Vega: OTTHUMG00000031236
Pharos: Q08345(Tchem)
UniProt: Q08345 A0A024RCL1
Structure
PDB: 

Position
6p21.33
AA seq 913 aa AA seqDB search
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR
HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL
RYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDD
FRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGG
VECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILI
GCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPRE
PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGPPTPAWAKPTNT
QAYSGDYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGP
PRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD
ATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED
KAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTI
KIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLC
RAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQ
LHRFLAEDALNTV
NT seq 2742 nt NT seq  +upstreamnt  +downstreamnt
atgggaccagaggccctgtcatctttactgctgctgctcttggtggcaagtggagatgct
gacatgaagggacattttgatcctgccaagtgccgctatgccctgggcatgcaggaccgg
accatcccagacagtgacatctctgcttccagctcctggtcagattccactgccgcccgc
cacagcaggttggagagcagtgacggggatggggcctggtgccccgcagggtcggtgttt
cccaaggaggaggagtacttgcaggtggatctacaacgactgcacctggtggctctggtg
ggcacccagggacggcatgccgggggcctgggcaaggagttctcccggagctaccggctg
cgttactcccgggatggtcgccgctggatgggctggaaggaccgctggggtcaggaggtg
atctcaggcaatgaggaccctgagggagtggtgctgaaggaccttgggccccccatggtt
gcccgactggttcgcttctacccccgggctgaccgggtcatgagcgtctgtctgcgggta
gagctctatggctgcctctggagggatggactcctgtcttacaccgcccctgtggggcag
acaatgtatttatctgaggccgtgtacctcaacgactccacctatgacggacataccgtg
ggcggactgcagtatgggggtctgggccagctggcagatggtgtggtggggctggatgac
tttaggaagagtcaggagctgcgggtctggccaggctatgactatgtgggatggagcaac
cacagcttctccagtggctatgtggagatggagtttgagtttgaccggctgagggccttc
caggctatgcaggtccactgtaacaacatgcacacgctgggagcccgtctgcctggcggg
gtggaatgtcgcttccggcgtggccctgccatggcctgggagggggagcccatgcgccac
aacctagggggcaacctgggggaccccagagcccgggctgtctcagtgccccttggcggc
cgtgtggctcgctttctgcagtgccgcttcctctttgcggggccctggttactcttcagc
gaaatctccttcatctctgatgtggtgaacaattcctctccggcactgggaggcaccttc
ccgccagccccctggtggccgcctggcccacctcccaccaacttcagcagcttggagctg
gagcccagaggccagcagcccgtggccaaggccgaggggagcccgaccgccatcctcatc
ggctgcctggtggccatcatcctgctcctgctgctcatcattgccctcatgctctggcgg
ctgcactggcgcaggctcctcagcaaggctgaacggagggtgttggaagaggagctgacg
gttcacctctctgtccctggggacactatcctcatcaacaaccgcccaggtcctagagag
ccacccccgtaccaggagccccggcctcgtgggaatccgccccactccgctccctgtgtc
cccaatggctctgcgttgctgctctccaatccagcctaccgcctccttctggccacttac
gcccgtccccctcgaggcccgggcccccccacacccgcctgggccaaacccaccaacacc
caggcctacagtggggactatatggagcctgagaagccaggcgccccgcttctgccccca
cctccccagaacagcgtcccccattatgccgaggctgacattgttaccctgcagggcgtc
accgggggcaacacctatgctgtgcctgcactgcccccaggggcagtcggggatgggccc
cccagagtggatttccctcgatctcgactccgcttcaaggagaagcttggcgagggccag
tttggggaggtgcacctgtgtgaggtcgacagccctcaagatctggttagtcttgatttc
ccccttaatgtgcgtaagggacaccctttgctggtagctgtcaagatcttacggccagat
gccaccaagaatgccaggaatgatttcctgaaagaggtgaagatcatgtcgaggctcaag
gacccaaacatcattcggctgctgggcgtgtgtgtgcaggacgaccccctctgcatgatt
actgactacatggagaacggcgacctcaaccagttcctcagtgcccaccagctggaggac
aaggcagccgagggggcccctggggacgggcaggctgcgcaggggcccaccatcagctac
ccaatgctgctgcatgtggcagcccagatcgcctccggcatgcgctatctggccacactc
aactttgtacatcgggacctggccacgcggaactgcctagttggggaaaatttcaccatc
aaaatcgcagactttggcatgagccggaacctctatgctggggactattaccgtgtgcag
ggccgggcagtgctgcccatccgctggatggcctgggagtgcatcctcatggggaagttc
acgactgcgagtgacgtgtgggcctttggtgtgaccctgtgggaggtgctgatgctctgt
agggcccagccctttgggcagctcaccgacgagcaggtcatcgagaacgcgggggagttc
ttccgggaccagggccggcaggtgtacctgtcccggccgcctgcctgcccgcagggccta
tatgagctgatgcttcggtgctggagccgggagtctgagcagcgaccacccttttcccag
ctgcatcggttcctggcagaggatgcactcaacacggtgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (25)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (22)   
DNA sequence (66)   
   RefSeq(nuc) (22)   
   GenBank (22)   
   EMBL (22)   
Protein domain (6)   
   Pfam (6)   
All databases (136)   

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