KEGG   Homo sapiens (human): 79053
Entry
79053             CDS       T01001                                 
Symbol
ALG8, CDG1H, PCLD3
Name
(RefSeq) ALG8 alpha-1,3-glucosyltransferase
  KO
K03849  alpha-1,3-glucosyltransferase [EC:2.4.1.265]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00510  N-Glycan biosynthesis
hsa01100  Metabolic pathways
Module
hsa_M00055  N-glycan precursor biosynthesis
Network
nt06015  N-Glycan biosynthesis
  Element
N00681  N-Glycan precursor biosynthesis, ALG6 to OST
Disease
H00118  Congenital disorders of glycosylation type I
H00545  Polycystic liver disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    79053 (ALG8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    79053 (ALG8)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.265  dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase
     79053 (ALG8)
Glycosyltransferases [BR:hsa01003]
 N-Glycan biosynthesis
  Dol-linked oligosaccharide
   79053 (ALG8)
SSDB
Motif
Pfam: Alg6_Alg8
Other DBs
NCBI-GeneID: 79053
NCBI-ProteinID: NP_076984
OMIM: 608103
HGNC: 23161
Ensembl: ENSG00000159063
UniProt: Q9BVK2 A0A024R5K5
Position
11:complement(78100946..78139626)
AA seq 526 aa
MAALTIATGTGNWFSALALGVTLLKCLLIPTYHSTDFEVHRNWLAITHSLPISQWYYEAT
SEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYA
VRECCKCIDGKKVGKELTEKPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARL
FQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIRWKSFSFVRVIS
LGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIG
LKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPR
GFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLFPL
LFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPF
TSWKVKYPFIPLLLTSVYCAVGITYAWFKLYVSVLIDSAIGKTKKQ
NT seq 1581 nt   +upstreamnt  +downstreamnt
atggcggcgctcacaattgccacgggtactggcaattggttttcggctttggcgctcggg
gtgactcttctcaaatgccttctcatccccacataccattccacagattttgaagtacac
cgaaactggcttgctatcactcacagtttgccaatatcacagtggtattatgaggcaact
tcagagtggacgttggattacccccctttctttgcatggtttgagtatatcctgtcacat
gttgccaaatattttgatcaagaaatgctgaatgtccataatttgaattactccagctca
aggaccttacttttccagagattttccgtcatctttatggatgtactctttgtgtatgct
gtccgtgagtgctgtaaatgcattgatggaaaaaaagtgggtaaagaacttacagaaaag
ccaaaatttattctgtcggtattacttctgtggaacttcgggttattaattgtggaccat
attcattttcagtacaatggctttttatttggattaatgctactctccattgcacgatta
tttcagaaaaggcatatggaaggagcatttctctttgctgttctcctacatttcaagcat
atctacctctatgtagcaccagcttatggtgtatatctgctgcgatcctactgtttcact
gcaaataaaccagatgggtctattcgatggaagagtttcagctttgttcgtgttatttcc
ctgggactggttgttttcttagtttctgctctttcattgggtcctttcctggccttgaat
cagctgcctcaagtcttttcccgactctttcctttcaagaggggcctctgtcatgcatat
tgggctccaaacttctgggctttgtacaatgctttggacaaagtgctgtctgtcatcggt
ttgaaattgaaatttcttgatcccaacaatattcccaaggcctcaatgacaagtggtttg
gttcagcagttccaacacacagtccttccctcagtgactcccttggcaaccctcatctgc
acactgattgccatattgccctctattttctgtctttggtttaaaccccaagggcccaga
ggctttctccgatgtctaactctttgtgccttgagctcctttatgtttgggtggcatgtt
catgaaaaagccatacttctagcaattctcccaatgagccttttgtctgtgggaaaagca
ggagacgcttcgatttttctgattctgaccacaacaggacattattccctctttcctctg
ctcttcactgcaccagaacttcccattaaaatcttactcatgttactattcaccatatat
agtatttcgtcactgaagactttattcagaaaagaaaaacctctttttaattggatggaa
actttctacctgcttggcctggggcctctggaagtctgctgtgaatttgtattccctttc
acctcctggaaggtgaagtaccccttcatccctttgttactaacctcagtgtattgtgca
gtaggcatcacatatgcttggttcaaactgtatgtttcagtattgattgactctgctatt
ggcaagacaaagaaacaatga

  All links  
Disease (3)   
   OMIM (3)   
Gene (14)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (34)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (31)   
DNA sequence (60)   
   RefSeq(nuc) (36)   
   GenBank (12)   
   EMBL (12)   
Protein domain (1)   
   Pfam (1)   
All databases (112)   

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