KEGG   Homo sapiens (human): 7919
Entry
7919              CDS       T01001                                 
Symbol
DDX39B, BAT1, D6S81E, UAP56
Name
(RefSeq) spliceosome RNA helicase DDX39B
  KO
K12812  ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa03015  mRNA surveillance pathway
hsa03040  Spliceosome
Network
nt06547  Spliceosome
  Element
N01968  Spliceosome assembly (E and A complex formation)
N01995  mRNA export to the cytoplasm
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    7919 (DDX39B)
  09122 Translation
   03013 Nucleocytoplasmic transport
    7919 (DDX39B)
   03015 mRNA surveillance pathway
    7919 (DDX39B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    7919 (DDX39B)
   03041 Spliceosome [BR:hsa03041]
    7919 (DDX39B)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.7  DEAD-box RNA helicase
     7919 (DDX39B)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    EJC complex
     7919 (DDX39B)
Spliceosome [BR:hsa03041]
 Complex C
  Other components
   EJC/TREX
    7919 (DDX39B)
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   TREX complex
    7919 (DDX39B)
SSDB
Motif
Pfam: DEAD Helicase_C ResIII CMS1 Cas3-like_C_2
Other DBs
NCBI-GeneID: 7919
NCBI-ProteinID: NP_004631
OMIM: 142560
HGNC: 13917
Ensembl: ENSP00000379475.1
UniProt: Q13838 A0A024RCM3
Structure
Position
6:complement(31530226..31542003)
AA seq 428 aa
MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
SSYIEQTR
NT seq 1287 nt   +upstreamnt  +downstreamnt
atggcagagaacgatgtggacaatgagctcttggactatgaagatgatgaggtggagaca
gcagctgggggagatggggctgaggcccctgccaagaaggatgtcaagggctcctatgtc
tccatccacagctctggctttcgtgacttcctgctcaagccagagttgctccgggccatt
gtcgactgtggctttgagcatccgtcagaagtccagcatgagtgcatccctcaggccatt
ctgggaatggatgtcctgtgccaggccaagtcgggcatgggaaagacagcagtgtttgtc
ttggccacactgcaacagctggagccagttactgggcaggtgtctgtactggtgatgtgt
cacactcgggagttggcttttcagatcagcaaggaatatgagcgcttctctaaatacatg
cccaatgtcaaggttgctgttttttttggtggtctgtctatcaagaaggatgaagaggtg
ctgaagaagaactgcccgcatatcgtcgtggggactccaggccgtatcctagccctggct
cgaaataagagcctcaacctcaaacacattaaacactttattttggatgaatgtgataag
atgcttgaacagctcgacatgcgtcgggatgtccaggaaatttttcgcatgaccccccac
gagaagcaggtcatgatgttcagtgctaccttgagcaaagagatccgtccagtctgccgc
aagttcatgcaagatccaatggagatcttcgtggatgatgagacgaagttgacgctgcat
gggttgcagcagtactacgtgaaactgaaggacaacgagaagaaccggaagctctttgac
cttctggatgtccttgagttcaaccaggtggtgatctttgtgaagtctgtgcagcggtgc
attgccttggcccagctactagtggagcagaacttcccagccattgccatccaccgtggg
atgccccaggaggagaggctttctcggtatcagcagtttaaagattttcaacgacgaatt
cttgtggctaccaacctatttggccgaggcatggacatcgagcgggtgaacattgctttt
aattatgacatgcctgaggattctgacacctacctgcatcgggtggccagagcaggccgg
tttggcaccaagggcttggctatcacatttgtgtccgatgagaatgatgccaagatcctc
aatgatgtgcaggatcgctttgaggtcaatattagtgagctgcctgatgagatagacatc
tcctcctacattgaacagacacggtag

  All links  
Disease (1)   
   OMIM (1)   
Gene (44)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (35)   
   RefSeq(nuc) (3)   
   GenBank (16)   
   EMBL (16)   
3D Structure (10)   
   PDB (10)   
Protein domain (5)   
   Pfam (5)   
All databases (100)   

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