KEGG   Homo sapiens (human): 79728Help
Entry
79728             CDS       T01001                                 

Gene name
PALB2, FANCN, PNCA3
Definition
(RefSeq) partner and localizer of BRCA2
  KO
K10897  partner and localizer of BRCA2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03440  Homologous recombination
hsa03460  Fanconi anemia pathway
Disease
H00238  Fanconi anemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    79728 (PALB2)
   03460 Fanconi anemia pathway
    79728 (PALB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    79728 (PALB2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    BRCA complex
     79728 (PALB2)
   FA (Fanconi anemia) pathway
    Downstream FA components
     79728 (PALB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PALB2_WD40
Motif
Other DBs
NCBI-GeneID: 79728
NCBI-ProteinID: NP_078951
OMIM: 610355
HGNC: 26144
Ensembl: ENSG00000083093
Vega: OTTHUMG00000177097
Pharos: Q86YC2(Tbio)
UniProt: Q86YC2
Structure
PDB: 

Position
16p12.2
AA seq 1186 aa AA seqDB search
MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQ
QDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQR
TDDTQEHFPHRVSDPSGEQKQKLPSRRKKQQKRTFISQERDCVFGTDSLRLSGKRLKEQE
EISSKNPARSPVTEIRTHLLSLKSELPDSPEPVTEINEDSVLIPPTAQPEKGVDTFLRRP
NFTRATTVPLQTLSDSGSSQHLEHIPPKGSSELTTHDLKNIRFTSPVSLEAQGKKMTVST
DNLLVNKAISKSGQLPTSSNLEANISCSLNELTYNNLPANENQNLKEQNQTEKSLKSPSD
TLDGRNENLQESEILSQPKSLSLEATSPLSAEKHSCTVPEGLLFPAEYYVRTTRSMSNCQ
RKVAVEAVIQSHLDVKKKGFKNKNKDASKNLNLSNEETDQSEIRMSGTCTGQPSSRTSQK
LLSLTKVSSPAGPTEDNDLSRKAVAQAPGRRYTGKRKSACTPASDHCEPLLPTSSLSIVN
RSKEEVTSHKYQHEKLFIQVKGKKSRHQKEDSLSWSNSAYLSLDDDAFTAPFHRDGMLSL
KQLLSFLSITDFQLPDEDFGPLKLEKVKSCSEKPVEPFESKMFGERHLKEGSCIFPEELS
PKRMDTEMEDLEEDLIVLPGKSHPKRPNSQSQHTKTGLSSSILLYTPLNTVAPDDNDRPT
TDMCSPAFPILGTTPAFGPQGSYEKASTEVAGRTCCTPQLAHLKDSVCLASDTKQFDSSG
SPAKPHTTLQVSGRQGQPTCDCDSVPPGTPPPIESFTFKENQLCRNTCQELHKHSVEQTE
TAELPASDSINPGNLQLVSELKNPSGSCSVDVSAMFWERAGCKEPCIITACEDVVSLWKA
LDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSSDDESEKQVL
LKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQ
GMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHKAYSEMGLLFIVLSHPCAK
ESESLRSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILTSGTIAIW
DLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLAGQKDGNIFVYHYS
NT seq 3561 nt NT seq  +upstreamnt  +downstreamnt
atggacgagcctcccgggaagcccctcagctgtgaggagaaggaaaagttaaaggagaaa
ttagcattcttgaaaagggaatacagcaagacactagcccgccttcagcgtgcccaaaga
gctgaaaagattaagcattctattaagaaaacagtagaagaacaagattgtttgtctcag
caggatctctcaccgcagctaaaacactcagaacctaaaaataaaatatgtgtttatgac
aagttacacatcaaaacccatcttgatgaagaaactggagaaaagacatctatcacactt
gatgttgggcctgagtcctttaaccctggagatggcccaggaggattacctatacaaaga
acagatgacacccaagaacattttccccacagggtcagtgaccctagtggtgagcaaaag
cagaagctgccaagcagaagaaagaagcagcagaagaggacatttatttcacaggagaga
gactgtgtctttggcactgattcactcagattgtctgggaaaagactaaaggaacaggaa
gaaatcagtagcaaaaatcctgctagatcaccagtaactgaaataagaactcacctttta
agtcttaaatctgaacttccagattctccagaaccagttacagaaattaatgaagacagt
gtattaattccaccaactgcccaaccagaaaaaggtgttgatacattcctaagaagacct
aatttcaccagggcgactacagttcctttacagactctatcagatagcggtagtagtcag
caccttgaacacattcctcctaaaggtagcagtgaacttactactcacgacctaaaaaac
attagatttacttcacctgtaagtttggaggcacaaggcaaaaaaatgactgtctctaca
gataacctccttgtaaataaagctataagtaaaagtggccaactgcccacaagttctaat
ttagaggcaaatatttcatgttctctaaatgaactcacctacaataacttaccagcaaat
gaaaaccaaaacttaaaagaacaaaatcaaacagagaaatctttaaaatctcccagtgac
actcttgatggcaggaatgaaaatcttcaggaaagtgagattctaagtcaacctaagagt
cttagcctggaagcaacctctcctctttctgcagaaaaacattcttgcacagtgcctgaa
ggccttctgtttcctgcagaatattatgttagaacaacacgaagcatgtccaattgccag
aggaaagtagccgtggaggctgtcattcagagtcatttggatgtcaagaaaaaagggttt
aaaaataaaaataaggatgcaagtaaaaatttaaacctttccaatgaggaaactgaccaa
agtgaaattaggatgtctggcacatgcacaggacaaccaagttcaagaacctctcagaaa
cttctctcattaactaaagtcagctctcccgctgggcccactgaagataatgacttgtct
aggaaggcagttgcccaagcacctggtagaagatacacaggaaaaagaaaatcagcctgc
accccagcatcagatcattgtgaaccacttttgccaacttctagcctgtcgattgttaac
aggtccaaggaagaagtcacctcacacaaatatcagcacgaaaaattatttattcaagtg
aaagggaagaaaagtcgtcatcaaaaagaggattccctttcttggagtaatagtgcttat
ttatccttggatgatgatgctttcacggctccatttcatagggatggaatgctgagttta
aagcaactactgtcttttctcagtatcacagactttcagttacctgatgaagactttgga
cctcttaagcttgaaaaagtgaagtcctgctcagaaaaaccagtggagccctttgagtca
aaaatgtttggagagagacatcttaaagagggaagctgtatttttccagaggaactgagt
cctaaacgcatggatacagaaatggaggacttagaagaggaccttattgttctaccagga
aaatcacatcccaaaaggccaaactcgcaaagccagcatacaaagacgggcctttcttca
tccatattactttatactcctttaaatacggttgcgcctgatgataatgacaggcctacc
acagacatgtgttcacctgctttccccatcttaggtactactccagcctttggccctcaa
ggctcctatgaaaaagcatctacagaagttgctggacgaacttgctgcacaccccaactt
gctcatttgaaagactcagtctgtcttgccagtgatactaaacaattcgacagttcaggc
agcccagcaaaaccacataccaccctgcaagtgtcaggcaggcaaggacaacctacctgt
gactgtgactctgtcccgccaggaacacctccacccattgagtcattcacttttaaagaa
aatcagctctgtagaaacacatgccaggagctgcataaacattccgtcgaacagactgaa
acagcagagcttcctgcttctgatagcataaacccaggcaacctacaattggtttcagag
ttaaagaatccttcaggttcctgttccgtagatgtgagtgccatgttttgggaaagagcc
ggttgtaaagagccatgtatcataactgcttgcgaagatgtagtttctctttggaaagct
ctggatgcttggcagtgggaaaaactttatacctggcacttcgcagaggttccagtatta
cagatagttccagtgcctgatgtgtataatctcgtgtgtgtagctttgggaaatttggaa
atcagagagatcagggcattgttttgttcctctgatgatgaaagtgaaaagcaagtacta
ctgaagtctggaaatataaaagctgtgcttggcctgacaaagaggaggctagttagtagc
agtgggaccctttctgatcaacaagtagaagtcatgacgtttgcagaagatggaggaggc
aaagaaaaccaatttttgatgccccctgaggagactatactaacttttgctgaggtccaa
gggatgcaagaagctctgcttggtactactattatgaacaacattgttatttggaattta
aaaactggtcaactcctgaaaaagatgcacattgatgattcttaccaagcttcagtctgt
cacaaagcctattctgaaatggggcttctctttattgtcctgagtcatccctgtgccaaa
gagagtgagtcgttgcgaagccctgtgtttcagctcattgtgattaaccctaagacgact
ctcagcgtgggtgtgatgctgtactgtcttcctccagggcaggctggcaggttcctggaa
ggtgacgtgaaagatcactgtgcagcagcaatcttgacttctggaacaattgccatttgg
gacttacttctcggtcagtgtactgccctcctcccacctgtctctgaccaacattggtct
tttgtgaaatggtcgggtacagactctcatttgctggctggacaaaaagatggaaatata
tttgtataccactattcataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (5)   
   KEGG DISEASE (1)   
   OMIM (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (59)   
   RefSeq(nuc) (7)   
   GenBank (26)   
   EMBL (26)   
Protein domain (1)   
   Pfam (1)   
All databases (108)   

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