KEGG   Homo sapiens (human): 8019
Entry
8019              CDS       T01001                                 
Symbol
BRD3, FSHRG2, ORFX, RING3L
Name
(RefSeq) bromodomain containing 3
  KO
K11721  bromodomain-containing protein 3
Organism
hsa  Homo sapiens (human)
Drug target
Apabetalone: D11131
Birabresib: D10911
Pelabresib: D12266
Repibresib: D13101
Trotabresib: D12006
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8019 (BRD3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8019 (BRD3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  BRD family [OT]
   8019 (BRD3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Chromatin remodeling factors
   Other chromatin remodeling factors
    8019 (BRD3)
SSDB
Motif
Pfam: Bromodomain BET
Other DBs
NCBI-GeneID: 8019
NCBI-ProteinID: NP_031397
OMIM: 601541
HGNC: 1104
Ensembl: ENSG00000169925
UniProt: Q15059
Structure
Position
9:complement(134030305..134068548)
AA seq 726 aa
MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
DSSDSE
NT seq 2181 nt   +upstreamnt  +downstreamnt
atgtccaccgccacgacagtcgcccccgcggggatcccggcgaccccgggccctgtgaac
ccaccccccccggaggtctccaaccccagcaagcccggccgcaagaccaaccagctgcag
tacatgcagaatgtggtggtgaagacgctctggaaacaccagttcgcctggcccttctac
cagcccgtggacgcaatcaaattgaacctgccggattatcataaaataattaaaaaccca
atggatatggggactattaagaagagactagaaaataattattattggagtgcaagcgaa
tgtatgcaggacttcaacaccatgtttacaaattgttacatttataacaagcccacagat
gacatagtgctaatggcccaagctttagagaaaatttttctacaaaaagtggcccagatg
ccccaagaggaagttgaattattaccccctgctccaaagggcaaaggtcggaagccggct
gcgggagcccagagcgcaggtacacagcaagtggcggccgtgtcctctgtctccccagcg
accccctttcagagcgtgccccccaccgtctcccagacgcccgtcatcgctgccacccct
gtaccaaccatcactgcaaacgtcacgtcggtcccagtccccccagctgccgccccacct
cctcctgccacacccatcgtccccgtggtccctcctacgccgcctgtcgtcaagaaaaag
ggcgtgaagcggaaagcagacacaaccactcccacgacgtcggccatcactgccagccgg
agtgagtcgcccccgccgttgtcagaccccaagcaggccaaagtggtggcccggcgggag
agtggtggccgccccatcaagcctcccaagaaggacctggaggacggcgaggtgccccag
cacgcaggcaagaagggcaagctgtcggagcacctacgctactgcgacagcatcctcagg
gagatgctatccaagaagcacgcggcctacgcctggcccttctacaagccagtggatgcc
gaggccctggagctgcacgactaccacgacatcatcaagcacccgatggacctcagcacc
gtgaaaaggaagatggatggccgagagtacccagacgcacagggctttgctgctgatgtc
cggctgatgttctcgaattgctacaaatacaatcccccagaccacgaggttgtggccatg
gcccggaagctccaggacgtgtttgagatgaggtttgccaagatgccagatgagcccgtg
gaggcaccggcgctgcctgcccccgcggcccccatggtgagcaagggcgctgagagcagc
cgtagcagtgaggagagctcttcggactcaggcagctcggactcggaggaggagcgggcc
accaggctggcggagctgcaggagcagctgaaggccgtgcacgagcagctggccgccctg
tctcaggccccagtaaacaaaccaaagaagaagaaggagaagaaggagaaggagaagaag
aagaaggacaaggagaaggagaaggagaagcacaaagtgaaggccgaggaagagaagaag
gccaaggtggctccgcctgccaagcaggctcagcagaagaaggctcctgccaagaaggcc
aacagcacgaccacggccggcagacagctgaagaaaggcggcaagcaggcatctgcctcc
tacgactcagaggaagaggaggagggcctgcccatgagctacgatgaaaagcgccagctt
agcctggacatcaaccggctgcccggggagaagctgggccgggtagtgcacatcatccaa
tctcgggagccctcgctcagggactccaaccccgacgagatagaaattgactttgagact
ctgaaacccaccactttgcgggaactggagagatatgtcaagtcttgtttacagaaaaag
caaaggaaaccgttctcagcaagcgggaagaaacaggcagccaagtcgaaagaggagcta
gctcaggaaaagaagaaggagctggaaaagcgtctgcaggatgtcagcgggcagctgagc
agcagcaagaagcccgcccggaaagagaagcccggctcagcaccctcagggggcccgtcc
aggctcagcagcagcagctcctccgagtctgggagcagcagctccagcgggtccagctct
gacagcagtgactcagaatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (15)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (43)   
   RefSeq(nuc) (15)   
   GenBank (14)   
   EMBL (14)   
3D Structure (41)   
   PDB (41)   
Protein domain (2)   
   Pfam (2)   
All databases (119)   

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