KEGG   Homo sapiens (human): 80351
Entry
80351             CDS       T01001                                 
Symbol
TNKS2, ARTD6, PARP-5b, PARP-5c, PARP5B, PARP5C, TANK2, TNKL, pART6
Name
(RefSeq) tankyrase 2
  KO
K10799  tankyrase [EC:2.4.2.30]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    80351 (TNKS2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    80351 (TNKS2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.30  NAD+ ADP-ribosyltransferase
     80351 (TNKS2)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Termination Factors
   Other termination factors
    80351 (TNKS2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Pericentriolar materials (PCM)
    Other PCM proteins
     80351 (TNKS2)
SSDB
Motif
Pfam: Ank Ank_2 Ank_4 Ank_5 Ank_3 PARP Ank_KRIT1 SAM_2 SAM_1 SAM_EPH
Other DBs
NCBI-GeneID: 80351
NCBI-ProteinID: NP_079511
OMIM: 607128
HGNC: 15677
Ensembl: ENSG00000107854
UniProt: Q9H2K2
Structure
Position
10:91798426..91865475
AA seq 1166 aa
MSGRRCAGGGAACASAAAEAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKST
PLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNAR
DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE
LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK
DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG
ADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKH
PQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVV
KHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQL
LQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVS
VVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAA
AKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLAR
VKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAA
SYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT
PLDLVSADDVSALLTAAMPPSALPSCYKPQVLNGVRSPGATADALSSGPSSPSSLSAASS
LDNLSGSFSELSSVVSSSGTEGASSLEKKEVPGVDFSITQFVRNLGLEHLMDIFEREQIT
LDVLVEMGHKELKEIGINAYGHRHKLIKGVERLISGQQGLNPYLTLNTSGSGTILIDLSP
DDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEEN
HNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTG
CPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYV
IYRGEQAYPEYLITYQIMRPEGMVDG
NT seq 3501 nt   +upstreamnt  +downstreamnt
atgtcgggtcgccgctgcgccggcgggggagcggcctgcgcgagcgccgcggccgaggcc
gtggagccggccgcccgagagctgttcgaggcgtgccgcaacggggacgtggaacgagtc
aagaggctggtgacgcctgagaaggtgaacagccgcgacacggcgggcaggaaatccacc
ccgctgcacttcgccgcaggttttgggcggaaagacgtagttgaatatttgcttcagaat
ggtgcaaatgtccaagcacgtgatgatgggggccttattcctcttcataatgcatgctct
tttggtcatgctgaagtagtcaatctccttttgcgacatggtgcagaccccaatgctcga
gataattggaattatactcctctccatgaagctgcaattaaaggaaagattgatgtttgc
attgtgctgttacagcatggagctgagccaaccatccgaaatacagatggaaggacagca
ttggatttagcagatccatctgccaaagcagtgcttactggtgaatataagaaagatgaa
ctcttagaaagtgccaggagtggcaatgaagaaaaaatgatggctctactcacaccatta
aatgtcaactgccacgcaagtgatggcagaaagtcaactccattacatttggcagcagga
tataacagagtaaagattgtacagctgttactgcaacatggagctgatgtccatgctaaa
gataaaggtgatctggtaccattacacaatgcctgttcttatggtcattatgaagtaact
gaacttttggtcaagcatggtgcctgtgtaaatgcaatggacttgtggcaattcactcct
cttcatgaggcagcttctaagaacagggttgaagtatgttctcttctcttaagttatggt
gcagacccaacactgctcaattgtcacaataaaagtgctatagacttggctcccacacca
cagttaaaagaaagattagcatatgaatttaaaggccactcgttgctgcaagctgcacga
gaagctgatgttactcgaatcaaaaaacatctctctctggaaatggtgaatttcaagcat
cctcaaacacatgaaacagcattgcattgtgctgctgcatctccatatcccaaaagaaag
caaatatgtgaactgttgctaagaaaaggagcaaacatcaatgaaaagactaaagaattc
ttgactcctctgcacgtggcatctgagaaagctcataatgatgttgttgaagtagtggtg
aaacatgaagcaaaggttaatgctctggataatcttggtcagacttctctacacagagct
gcatattgtggtcatctacaaacctgccgcctactcctgagctatgggtgtgatcctaac
attatatcccttcagggctttactgctttacagatgggaaatgaaaatgtacagcaactc
ctccaagagggtatctcattaggtaattcagaggcagacagacaattgctggaagctgca
aaggctggagatgtcgaaactgtaaaaaaactgtgtactgttcagagtgtcaactgcaga
gacattgaagggcgtcagtctacaccacttcattttgcagctgggtataacagagtgtcc
gtggtggaatatctgctacagcatggagctgatgtgcatgctaaagataaaggaggcctt
gtacctttgcacaatgcatgttcttatggacattatgaagttgcagaacttcttgttaaa
catggagcagtagttaatgtagctgatttatggaaatttacacctttacatgaagcagca
gcaaaaggaaaatatgaaatttgcaaacttctgctccagcatggtgcagaccctacaaaa
aaaaacagggatggaaatactcctttggatcttgttaaagatggagatacagatattcaa
gatctgcttaggggagatgcagctttgctagatgctgccaagaagggttgtttagccaga
gtgaagaagttgtcttctcctgataatgtaaattgccgcgatacccaaggcagacattca
acacctttacatttagcagctggttataataatttagaagttgcagagtatttgttacaa
cacggagctgatgtgaatgcccaagacaaaggaggacttattcctttacataatgcagca
tcttacgggcatgtagatgtagcagctctactaataaagtataatgcatgtgtcaatgcc
acggacaaatgggctttcacacctttgcacgaagcagcccaaaagggacgaacacagctt
tgtgctttgttgctagcccatggagctgacccgactcttaaaaatcaggaaggacaaaca
cctttagatttagtttcagcggatgatgtcagcgctcttctgacagcagccatgccccca
tctgctctgccctcttgttacaagcctcaagtgctcaatggtgtgagaagcccaggagcc
actgcagatgctctctcttcaggtccatctagcccatcaagcctttctgcagccagcagt
cttgacaacttatctgggagtttttcagaactgtcttcagtagttagttcaagtggaaca
gagggtgcttccagtttggagaaaaaggaggttccaggagtagattttagcataactcaa
ttcgtaaggaatcttggacttgagcacctaatggatatatttgagagagaacagatcact
ttggatgtattagttgagatggggcacaaggagctgaaggagattggaatcaatgcttat
ggacataggcacaaactaattaaaggagtcgagagacttatctccggacaacaaggtctt
aacccatatttaactttgaacacctctggtagtggaacaattcttatagatctgtctcct
gatgataaagagtttcagtctgtggaggaagagatgcaaagtacagttcgagagcacaga
gatggaggtcatgcaggtggaatcttcaacagatacaatattctcaagattcagaaggtt
tgtaacaagaaactatgggaaagatacactcaccggagaaaagaagtttctgaagaaaac
cacaaccatgccaatgaacgaatgctatttcatgggtctccttttgtgaatgcaattatc
cacaaaggctttgatgaaaggcatgcgtacataggtggtatgtttggagctggcatttat
tttgctgaaaactcttccaaaagcaatcaatatgtatatggaattggaggaggtactggg
tgtccagttcacaaagacagatcttgttacatttgccacaggcagctgctcttttgccgg
gtaaccttgggaaagtctttcctgcagttcagtgcaatgaaaatggcacattctcctcca
ggtcatcactcagtcactggtaggcccagtgtaaatggcctagcattagctgaatatgtt
atttacagaggagaacaggcttatcctgagtatttaattacttaccagattatgaggcct
gaaggtatggtcgatggataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (23)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (34)   
   RefSeq(nuc) (12)   
   GenBank (11)   
   EMBL (11)   
3D Structure (167)   
   PDB (167)   
Protein domain (10)   
   Pfam (10)   
All databases (249)   

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