KEGG   Homo sapiens (human): 81620
Entry
81620             CDS       T01001                                 
Symbol
CDT1, DUP, RIS2
Name
(RefSeq) chromatin licensing and DNA replication factor 1
  KO
K10727  chromatin licensing and DNA replication factor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06509  DNA replication
  Element
N01468  DNA replication licensing
N01469  Cdt1 downregulation
N01470  Pre-IC formation
Disease
H01889  Meier-Gorlin syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    81620 (CDT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    81620 (CDT1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    81620 (CDT1)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   pre-RC (pre-replication complex)
    81620 (CDT1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     81620 (CDT1)
SSDB
Motif
Pfam: CDT1 CDT1_C
Other DBs
NCBI-GeneID: 81620
NCBI-ProteinID: NP_112190
OMIM: 605525
HGNC: 24576
Ensembl: ENSG00000167513
UniProt: Q9H211
Structure
Position
16:88803789..88809258
AA seq 546 aa
MEQRRVTDFFARRRPGPPRIAPPKLACRTPSPARPALRAPASATSGSRKRARPPAAPGRD
QARPPARRRLRLSVDEVSSPSTPEAPDIPACPSPGQKIKKSTPAAGQPPHLTSAQDQDTI
SELASCLQRARELGARVRALKASAQDAGESCTPEAEGRPEEPCGEKAPAYQRFHALAQPG
LPGLVLPYKYQVLAEMFRSMDTIVGMLHNRSETPTFAKVQRGVQDMMRRRFEECNVGQIK
TVYPASYRFRQERSVPTFKDGTRRSDYQLTIEPLLEQEADGAAPQLTASRLLQRRQIFSQ
KLVEHVKEHHKAFLASLSPAMVVPEDQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTA
QEVLARARNLISPRMEKALSQLALRSAAPSSPGSPRPALPATPPATPPAASPSALKGVSQ
DLLERIRAKEAQKQLAQMTRCPEQEQRLQRLERLPELARVLRSVFVSERKPALSMEVACA
RMVGSCCTIMSPGEMEKHLLLLSELLPDWLSLHRIRTDTYVKLDKAADLAHITARLAHQT
RAEEGL
NT seq 1641 nt   +upstreamnt  +downstreamnt
atggagcagcgccgcgtcaccgacttcttcgcgcgccgccgccccgggcccccccgcatc
gcgccgcccaagctggcctgccgcacccccagccccgccaggcccgcactccgcgccccg
gcctccgctaccagtggcagccgcaagcgcgcccgcccgcccgccgcccccggacgcgac
caggccaggccaccggcccgcaggagactgcggctgtcggtggacgaggtttccagcccc
agtacccccgaggccccagacatcccagcctgcccttctccgggccagaagataaagaaa
tccaccccggcagcaggtcagccgccccacctgacatccgcgcaggaccaggacaccatc
tctgagcttgcgtcatgcctgcaacgggcccgggagctgggggcaagagtccgggcgctg
aaggccagtgcccaggatgctggggagtcctgcaccccagaggccgagggccgccctgag
gagccatgtggcgagaaggcgcccgcctaccagcgcttccatgccctggcccagcccggc
ctgccgggactcgtgctgccctacaagtaccaggtgctggcggagatgttccgcagcatg
gacaccatcgtgggcatgctccacaaccgctccgagacgcccacctttgccaaggtccag
cggggcgtccaggacatgatgcgtaggcgttttgaggagtgcaatgttggccagatcaaa
accgtgtacccggcctcctaccgcttccgccaggagcgcagtgtccccaccttcaaggat
ggcaccaggaggtcagattaccagctcaccatcgagccactgctggagcaggaggctgac
ggagcagccccccagctcacggcctcgcgcctcctgcagcgacggcagatcttcagccag
aagctggtggagcatgtcaaggagcaccacaaggccttcctggcctccctgagccccgcc
atggtggtgccggaggaccagctgacccgctggcacccgcgcttcaacgtggatgaagta
cccgacatcgagccggccgcgctgccccagccacccgccacggagaagctcaccactgct
caggaggtgctggcccgggcccgcaacctgatttcacccaggatggagaaggccttgagt
caattggccctgcgctctgctgcgcccagcagccccgggtctcccaggccagcactgccg
gctaccccaccagccaccccgcctgcagcctctcccagtgctctgaagggggtgtcccag
gatctgctggagcggatccgagccaaggaggcacagaagcagctggcacagatgacgcgg
tgcccggagcaggagcagcggctgcagcgcttagaacggctgcctgagctggcccgcgtg
ctgcggagcgtctttgtgtccgaacgcaagcctgcgctcagcatggaggtggcctgtgcc
aggatggtgggcagctgttgtactatcatgagccctggggaaatggagaagcacctgctg
ctcctctccgagctgctgccggactggctcagcctccaccgcatccgcaccgacacctac
gtcaagctggacaaggccgcggacctcgcccacatcactgcacgcctggcccaccagaca
cgtgctgaggaggggctgtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (50)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (17)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (6)   
   PDB (6)   
Protein domain (2)   
   Pfam (2)   
All databases (84)   

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