KEGG   Homo sapiens (human): 821
Entry
821               CDS       T01001                                 
Symbol
CANX, CNX, IP90, P90
Name
(RefSeq) calnexin
  KO
K08054  calnexin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04145  Phagosome
hsa04612  Antigen processing and presentation
hsa04918  Thyroid hormone synthesis
hsa05166  Human T-cell leukemia virus 1 infection
Network
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06220  Calcium signaling (cancer)
nt06537  TCR/BCR signaling
  Element
N00490  HTLV-1 p12 to calcineurin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    821 (CANX)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    821 (CANX)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    821 (CANX)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    821 (CANX)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    821 (CANX)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    821 (CANX)
   04131 Membrane trafficking [BR:hsa04131]
    821 (CANX)
  09183 Protein families: signaling and cellular processes
   04091 Lectins [BR:hsa04091]
    821 (CANX)
Chaperones and folding catalysts [BR:hsa03110]
 Other chaperones and cochaperones
  Calnexin / calreticulin
   821 (CANX)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Others
    821 (CANX)
 Autophagy
  ER-phagy
   Other ER-phagy associated proteins
    821 (CANX)
Lectins [BR:hsa04091]
 L-type lectins
  821 (CANX)
SSDB
Motif
Pfam: Calreticulin Connexin FAM176 MAP17 PFF1_TM CFAP143 Folate_carrier V_ATPase_I Piezo_TM1-24
Other DBs
NCBI-GeneID: 821
NCBI-ProteinID: NP_001019820
OMIM: 114217
HGNC: 1473
Ensembl: ENSG00000127022
UniProt: P27824
Position
5:179678656..179731641
AA seq 592 aa
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
NT seq 1779 nt   +upstreamnt  +downstreamnt
atggaagggaagtggttgctgtgtatgttactggtgcttggaactgctattgttgaggct
catgatggacatgatgatgatgtgattgatattgaggatgaccttgacgatgtcattgaa
gaggtagaagactcaaaaccagataccactgctcctccttcatctcccaaggttacttac
aaagctccagttccaacaggggaagtatattttgctgattcttttgacagaggaactctg
tcagggtggattttatccaaagccaagaaagacgataccgatgatgaaattgccaaatat
gatggaaagtgggaggtagaggaaatgaaggagtcaaagcttccaggtgataaaggactt
gtgttgatgtctcgggccaagcatcatgccatctctgctaaactgaacaagcccttcctg
tttgacaccaagcctctcattgttcagtatgaggttaatttccaaaatggaatagaatgt
ggtggtgcctatgtgaaactgctttctaaaacaccagaactcaacctggatcagttccat
gacaagaccccttatacgattatgtttggtccagataaatgtggagaggactataaactg
cacttcatcttccgacacaaaaaccccaaaacgggtatctatgaagaaaaacatgctaag
aggccagatgcagatctgaagacctattttactgataagaaaacacatctttacacacta
atcttgaatccagataatagttttgaaatactggttgaccaatctgtggtgaatagtgga
aatctgctcaatgacatgactcctcctgtaaatccttcacgtgaaattgaggacccagaa
gaccggaagcccgaggattgggatgaaagaccaaaaatcccagatccagaagctgtcaag
ccagatgactgggatgaagatgcccctgctaagattccagatgaagaggccacaaaaccc
gaaggctggttagatgatgagcctgagtacgtacctgatccagacgcagagaaacctgag
gattgggatgaagacatggatggagaatgggaggctcctcagattgccaaccctagatgt
gagtcagctcctggatgtggtgtctggcagcgacctgtgattgacaaccccaattataaa
ggcaaatggaagcctcctatgattgacaatcccagttaccagggaatctggaaacccagg
aaaataccaaatccagatttctttgaagatctggaacctttcagaatgactccttttagt
gctattggtttggagctgtggtccatgacctctgacattttttttgacaactttatcatt
tgtgctgatcgaagaatagttgatgattgggccaatgatggatggggcctgaagaaagct
gctgatggggctgctgagccaggcgttgtggggcagatgatcgaggcagctgaagagcgc
ccgtggctgtgggtagtctatattctaactgtagcccttcctgtgttcctggttatcctc
ttctgctgttctggaaagaaacagaccagtggtatggagtataagaaaactgatgcacct
caaccggatgtgaaggaagaggaagaagagaaggaagaggaaaaggacaagggagatgag
gaggaggaaggagaagagaaacttgaagagaaacagaaaagtgatgctgaagaagatggt
ggcactgtcagtcaagaggaggaagacagaaaacctaaagcagaggaggatgaaattttg
aacagatcaccaagaaacagaaagccacgaagagagtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (19)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (49)   
   RefSeq(nuc) (17)   
   GenBank (16)   
   EMBL (16)   
Protein domain (9)   
   Pfam (9)   
All databases (96)   

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