KEGG   Homo sapiens (human): 8317
Entry
8317              CDS       T01001                                 
Symbol
CDC7, CDC7L1, HsCDC7, Hsk1, huCDC7
Name
(RefSeq) cell division cycle 7
  KO
K02214  cell division control protein 7 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06509  DNA replication
  Element
N01468  DNA replication licensing
Drug target
Simurosertib: D12176
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    8317 (CDC7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8317 (CDC7)
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    8317 (CDC7)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8317 (CDC7)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  CDC7 family
   8317 (CDC7)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   DDK (Dbf-4 dependent kinase)
    8317 (CDC7)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH ABC1
Other DBs
NCBI-GeneID: 8317
NCBI-ProteinID: NP_001127891
OMIM: 603311
HGNC: 1745
Ensembl: ENSG00000097046
UniProt: O00311 A0A384MTU6
Structure
Position
1:91500851..91525764
AA seq 574 aa
MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKI
EDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGV
KYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKP
SNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSG
PVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH
ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVC
SICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDD
LTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQ
GHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPD
EAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL
NT seq 1725 nt   +upstreamnt  +downstreamnt
atggaggcgtctttggggattcagatggatgagccaatggctttttctccccagcgtgac
cggtttcaggctgaaggctctttaaaaaaaaacgagcagaattttaaacttgcaggtgtt
aaaaaagatattgagaagctttatgaagctgtaccacagcttagtaatgtgtttaagatt
gaggacaaaattggagaaggcactttcagctctgtttatttggccacagcacagttacaa
gtaggacctgaagagaaaattgctctaaaacacttgattccaacaagtcatcctataaga
attgcagctgaacttcagtgcctaacagtggctggggggcaagataatgtcatgggagtt
aaatactgctttaggaagaatgatcatgtagttattgctatgccatatctggagcatgag
tcgtttttggacattctgaattctctttcctttcaagaagtacgggaatatatgcttaat
ctgttcaaagctttgaaacgcattcatcagtttggtattgttcaccgtgatgttaagccc
agcaattttttatataataggcgcctgaaaaagtatgccttggtagactttggtttggcc
caaggaacccatgatacgaaaatagagcttcttaaatttgtccagtctgaagctcagcag
gaaaggtgttcacaaaacaaatcccacataatcacaggaaacaagattccactgagtggc
ccagtacctaaggagctggatcagcagtccaccacaaaagcttctgttaaaagaccctac
acaaatgcacaaattcagattaaacaaggaaaagacggaaaggagggatctgtaggcctt
tctgtccagcgctctgtttttggagaaagaaatttcaatatacacagctccatttcacat
gagagccctgcagtgaaactcatgaagcagtcaaagactgtggatgtactgtctagaaag
ttagcaacaaaaaagaaggctatttctacaaaagttatgaatagtgctgtgatgaggaaa
actgccagttcttgcccagctagcctgacctgtgactgctatgcaacagataaagtttgt
agtatttgcctttcaaggcgtcagcaggttgcccctagggcaggtacaccaggattcaga
gcaccagaggtcttgacaaagtgccccaatcaaactacagcaattgacatgtggtctgca
ggtgtcatatttctttctttgcttagtggacgatatccattttataaagcaagtgatgat
ttaactgctttggcccaaattatgacaattaggggatccagagaaactatccaagctgct
aaaacttttgggaaatcaatattatgtagcaaagaagttccagcacaagacttgagaaaa
ctctgtgagagactcaggggtatggattctagcactcccaagttaacaagtgatatacaa
gggcatgcttctcatcaaccagctatttcagagaagactgaccataaagcttcttgcctc
gttcaaacacctccaggacaatactcagggaattcatttaaaaagggggatagtaatagc
tgtgagcattgttttgatgagtataataccaatttagaaggctggaatgaggtacctgat
gaagcttatgacctgcttgataaacttctagatctaaatccagcttcaagaataacagca
gaagaagctttgttgcatccattttttaaagatatgagcttgtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (16)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (34)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (31)   
DNA sequence (61)   
   RefSeq(nuc) (31)   
   GenBank (15)   
   EMBL (15)   
3D Structure (9)   
   PDB (9)   
Protein domain (4)   
   Pfam (4)   
All databases (125)   

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