KEGG   Homo sapiens (human): 838
Entry
838               CDS       T01001                                 

Gene name
CASP5, ICE(rel)III, ICEREL-III, ICH-3
Definition
(RefSeq) caspase 5
  KO
K04395  caspase 5 [EC:3.4.22.58]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05132  Salmonella infection
Network
nt06139  NLR signaling (viruses and bacteria)
  Element
N00934  Non-canonical inflammasome signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    838 (CASP5)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    838 (CASP5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    838 (CASP5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.58  caspase-5
     838 (CASP5)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C14: caspase family
   838 (CASP5)
SSDB
Motif
Pfam: Peptidase_C14 CARD DUF1338
Other DBs
NCBI-GeneID: 838
NCBI-ProteinID: NP_004338
OMIM: 602665
HGNC: 1506
Ensembl: ENSG00000137757
Vega: OTTHUMG00000048073
Pharos: P51878(Tchem)
UniProt: P51878
Position
11q22.3
AA seq 434 aa
MAEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVK
KDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDSLR
KNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESAESTNILKLCPREEFLRLCKKNHD
EIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARD
MESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNC
LSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAF
CSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIE
RATLTRDFYLFPGN
NT seq 1305 nt   +upstreamnt  +downstreamnt
atggctgaagacagtggcaaaaaaaaaaggcgtaagaattttgaagctatgttcaaaggt
atccttcagagtggattggataacttcgtgataaaccacatgctaaagaacaacgtggct
ggacaaacatctatccagaccctagtacctaatacggatcaaaagtcgaccagtgtaaaa
aaagacaaccacaaaaaaaaaacagttaagatgttggaatacctgggcaaagatgttctt
catggtgtttttaattatttggcaaaacacgatgttctgacattgaaggaagaggaaaag
aaaaaatattatgataccaaaattgaagacaaggccctgatcttggtagactctttgcga
aagaatcgcgtggctcatcaaatgtttacccaaacacttctcaatatggaccaaaagatc
accagtgtaaaacctcttctgcaaatcgaggctggaccacctgagtcagcagaatctaca
aatatactcaaactttgtcctcgtgaagaattcctgagactgtgtaaaaaaaatcatgat
gagatctatccaataaaaaagagagaggaccgcagacgcctggctctcatcatatgcaat
acaaagtttgatcacctgcctgcaaggaatggggctcactatgacatcgtggggatgaaa
aggctgcttcaaggcctgggctacactgtggttgacgaaaagaatctcacagccagggat
atggagtcagtgctgagggcatttgctgccagaccagagcacaagtcctctgacagcacg
ttcttggtactcatgtctcatggcatcctagagggaatctgcggaactgcgcataaaaag
aaaaaaccggatgtgctgctttatgacaccatcttccagatattcaacaaccgcaactgc
ctcagtctaaaggacaaacccaaggtcatcattgtccaggcctgcagaggtgaaaaacat
ggggaactctgggtcagagactctccagcatccttggcactcatctcttcacagtcatct
gagaacctggaggcagattctgtttgcaagatccacgaggagaaggacttcattgctttc
tgttcttcaacaccacataacgtgtcctggagagaccgcacaaggggctccatcttcatt
acggaactcatcacatgcttccagaaatattcttgctgctgccacctaatggaaatattt
cggaaggtacagaaatcatttgaagttccacaggctaaagcccagatgcccaccatagaa
cgagcaaccttgacaagagatttctacctctttcctggcaattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (1)   
   KEGG NETWORK (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (33)   
   RefSeq(nuc) (7)   
   GenBank (13)   
   EMBL (13)   
Protein domain (3)   
   Pfam (3)   
All databases (77)   

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