KEGG   Homo sapiens (human): 84188Help
Entry
84188             CDS       T01001                                 

Gene name
FAR1, MLSTD2, PFCRD, SDR10E1
Definition
(RefSeq) fatty acyl-CoA reductase 1
  KO
K13356  alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04146  Peroxisome
Disease
H00207  Rhizomelic chondrodysplasia punctata
H02100  Peroxisomal fatty acyl-CoA reductase 1 disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00073 Cutin, suberine and wax biosynthesis
    84188 (FAR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    84188 (FAR1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.84  alcohol-forming fatty acyl-CoA reductase
     84188 (FAR1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: NAD_binding_4 Sterile Epimerase Polysacc_synt_2 Semialdhyde_dh 3Beta_HSD GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID: 84188
NCBI-ProteinID: NP_115604
OMIM: 616107
HGNC: 26222
Ensembl: ENSG00000197601
Vega: OTTHUMG00000165743
Pharos: Q8WVX9(Tbio)
UniProt: Q8WVX9
Position
11p15.3
AA seq 515 aa AA seqDB search
MVSIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVL
SGKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNEN
LRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDS
LEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPF
PGWIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRNI
MVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAP
AFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTENVNMLMNQLNPEDKKT
FNIDVRQLHWAEYIENYCLGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWR
IFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY
NT seq 1548 nt NT seq  +upstreamnt  +downstreamnt
atggtttcaatcccagaatactatgaaggcaagaacgtcctcctcacaggagctaccggt
tttctagggaaggtgcttctggaaaagttgctgaggtcttgtcctaaggtgaattcagta
tatgttttggtgaggcagaaagctggacagacaccacaagagcgagtggaagaagtcctt
agtggcaagctttttgacagattgagagatgaaaatccagattttagagagaaaattata
gcaatcaacagcgaactcacccaacctaaactggctctcagtgaagaagataaagaggtg
atcatagattctaccaatattatattccactgtgcagctacagtaaggtttaatgaaaat
ttaagagatgctgttcagttaaatgtgattgcaacgcgacagcttattctccttgcacaa
caaatgaagaatctggaagtgttcatgcatgtatcaacagcatatgcctactgtaatcgc
aagcatattgatgaagtagtctatccaccacctgtggatcccaagaagctgattgattct
ttagagtggatggatgatggcctagtaaatgatatcacgccaaaattgataggagacaga
cctaatacatacatatacacaaaagcattggcagaatatgttgtacaacaagaaggagca
aaactaaatgtggcaattgtaaggccatcgattgttggtgccagttggaaagaacctttt
ccaggatggattgataactttaatggaccaagtggtctctttattgcggcagggaaagga
attcttcgaacaatacgtgcctccaacaatgcccttgcagatcttgttcctgtagatgta
gttgtcaacatgagtcttgcggcagcctggtattccggagttaatagaccaagaaacatc
atggtgtataattgtacaacaggcagcactaatcctttccactggggtgaagttgagtac
catgtaatttccactttcaagaggaatcctctcgaacaggccttcagacggcccaatgta
aatctaacctccaatcatcttttatatcattactggattgctgtaagccataaggcccca
gcattcctgtatgatatctacctcaggatgactggaagaagcccaaggatgatgaaaaca
ataactcgtcttcacaaagctatggtgtttcttgaatatttcacaagtaattcttgggtt
tggaatactgagaatgtcaatatgttaatgaatcaactaaaccctgaagataaaaagacc
ttcaatattgatgtacggcagttacattgggcagaatatatagagaactactgcttggga
actaagaagtacgtattgaatgaagaaatgtctggcctccctgcagccagaaaacatctg
aacaagttgcggaatatacgttatggttttaatactatccttgtgatcctcatctggcgc
atttttattgcaagatcacaaatggcaagaaatatctggtactttgtggttagtctgtgt
tacaagtttttgtcatacttccgagcatccagcactatgagatactga

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