KEGG   Homo sapiens (human): 84188
Entry
84188             CDS       T01001                                 

Gene name
FAR1, MLSTD2, PFCRD, SDR10E1
Definition
(RefSeq) fatty acyl-CoA reductase 1
  KO
K13356  alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04146  Peroxisome
Disease
H00207  Rhizomelic chondrodysplasia punctata
H02100  Peroxisomal fatty acyl-CoA reductase 1 disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00073 Cutin, suberine and wax biosynthesis
    84188 (FAR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    84188 (FAR1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.84  alcohol-forming fatty acyl-CoA reductase
     84188 (FAR1)
SSDB
Motif
Pfam: NAD_binding_4 Sterile Epimerase Polysacc_synt_2 Semialdhyde_dh 3Beta_HSD GDP_Man_Dehyd
Other DBs
NCBI-GeneID: 84188
NCBI-ProteinID: NP_115604
OMIM: 616107
HGNC: 26222
Ensembl: ENSG00000197601
Vega: OTTHUMG00000165743
Pharos: Q8WVX9(Tbio)
UniProt: Q8WVX9
Position
11p15.3
AA seq 515 aa
MVSIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVL
SGKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNEN
LRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDS
LEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPF
PGWIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRNI
MVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAP
AFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTENVNMLMNQLNPEDKKT
FNIDVRQLHWAEYIENYCLGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWR
IFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY
NT seq 1548 nt   +upstreamnt  +downstreamnt
atggtttcaatcccagaatactatgaaggcaagaacgtcctcctcacaggagctaccggt
tttctagggaaggtgcttctggaaaagttgctgaggtcttgtcctaaggtgaattcagta
tatgttttggtgaggcagaaagctggacagacaccacaagagcgagtggaagaagtcctt
agtggcaagctttttgacagattgagagatgaaaatccagattttagagagaaaattata
gcaatcaacagcgaactcacccaacctaaactggctctcagtgaagaagataaagaggtg
atcatagattctaccaatattatattccactgtgcagctacagtaaggtttaatgaaaat
ttaagagatgctgttcagttaaatgtgattgcaacgcgacagcttattctccttgcacaa
caaatgaagaatctggaagtgttcatgcatgtatcaacagcatatgcctactgtaatcgc
aagcatattgatgaagtagtctatccaccacctgtggatcccaagaagctgattgattct
ttagagtggatggatgatggcctagtaaatgatatcacgccaaaattgataggagacaga
cctaatacatacatatacacaaaagcattggcagaatatgttgtacaacaagaaggagca
aaactaaatgtggcaattgtaaggccatcgattgttggtgccagttggaaagaacctttt
ccaggatggattgataactttaatggaccaagtggtctctttattgcggcagggaaagga
attcttcgaacaatacgtgcctccaacaatgcccttgcagatcttgttcctgtagatgta
gttgtcaacatgagtcttgcggcagcctggtattccggagttaatagaccaagaaacatc
atggtgtataattgtacaacaggcagcactaatcctttccactggggtgaagttgagtac
catgtaatttccactttcaagaggaatcctctcgaacaggccttcagacggcccaatgta
aatctaacctccaatcatcttttatatcattactggattgctgtaagccataaggcccca
gcattcctgtatgatatctacctcaggatgactggaagaagcccaaggatgatgaaaaca
ataactcgtcttcacaaagctatggtgtttcttgaatatttcacaagtaattcttgggtt
tggaatactgagaatgtcaatatgttaatgaatcaactaaaccctgaagataaaaagacc
ttcaatattgatgtacggcagttacattgggcagaatatatagagaactactgcttggga
actaagaagtacgtattgaatgaagaaatgtctggcctccctgcagccagaaaacatctg
aacaagttgcggaatatacgttatggttttaatactatccttgtgatcctcatctggcgc
atttttattgcaagatcacaaatggcaagaaatatctggtactttgtggttagtctgtgt
tacaagtttttgtcatacttccgagcatccagcactatgagatactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (28)   
   RefSeq(nuc) (2)   
   GenBank (13)   
   EMBL (13)   
Protein domain (7)   
   Pfam (7)   
All databases (70)   

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