KEGG   Homo sapiens (human): 84335
Entry
84335             CDS       T01001                                 
Symbol
AKT1S1, Lobe, PRAS40
Name
(RefSeq) AKT1 substrate 1
  KO
K16184  proline-rich AKT1 substrate 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04150  mTOR signaling pathway
hsa04152  AMPK signaling pathway
hsa04211  Longevity regulating pathway
hsa04213  Longevity regulating pathway - multiple species
hsa04714  Thermogenesis
hsa05131  Shigellosis
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06461  Huntington disease
nt06462  Spinocerebellar ataxia
nt06466  Pathways of neurodegeneration
nt06522  mTOR signaling
nt06532  Autophagy
  Element
N00155  Autophagy-vesicle nucleation/elongation/maturation, mTORC1-PI3KC3-C1
N01575  TSC1/2-mTORC1 signaling pathway
N01578  GATOR1-mTORC1 signaling pathway
N01584  FLCN-mTORC1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    84335 (AKT1S1)
   04150 mTOR signaling pathway
    84335 (AKT1S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    84335 (AKT1S1)
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    84335 (AKT1S1)
   04213 Longevity regulating pathway - multiple species
    84335 (AKT1S1)
  09159 Environmental adaptation
   04714 Thermogenesis
    84335 (AKT1S1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    84335 (AKT1S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    84335 (AKT1S1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    84335 (AKT1S1)
SSDB
Motif
Pfam: PRAS PRAS_NT Senescence_reg
Other DBs
NCBI-GeneID: 84335
NCBI-ProteinID: NP_001092102
OMIM: 610221
HGNC: 28426
Ensembl: ENSG00000204673
Pharos: Q96B36(Tchem)
UniProt: Q96B36
Structure
Position
19:complement(49869033..49878356)
AA seq 256 aa
MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARR
CLHDIALAHRAATAARPPAPPPAPQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQL
GISDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQY
AKSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLP
RPRLNTSDFQKLKRKY
NT seq 771 nt   +upstreamnt  +downstreamnt
atggcgtcggggcgccccgaggagctgtgggaggccgtggtgggggccgctgagcgcttc
cgggcccggactggcacggagctggtgctgctgaccgcggccccgccgccaccaccccgc
ccgggcccctgtgcctatgctgcccatggtcgaggagccctggcggaggcagcgcgccgt
tgcctccacgacatcgcactggcccacagggctgccactgctgctcggcctcctgcgccc
ccaccagcaccacagccacccagtcccacacccagcccaccccggcctaccctggccaga
gaggacaacgaggaggacgaggatgagcccacagagacagagacctccggggagcagctg
ggcattagtgataatggagggctctttgtgatggatgaggacgccaccctccaggacctt
ccccccttctgtgagtcagaccccgagagtacagatgatggcagcctgagcgaggagacc
cccgccggcccccccacctgctcagtgcccccagcctcagccctacccacacagcagtac
gccaagtccctgcctgtgtctgtgcccgtctggggcttcaaggagaagaggacagaggcg
cggtcatcagatgaggagaatgggccgccctcttcgcccgacctggaccgcatcgcggcg
agcatgcgcgcgctggtgctgcgagaggccgaggacacccaggtcttcggggacctgcca
cggccgcggcttaacaccagcgacttccagaagctgaagcggaaatattga

DBGET integrated database retrieval system