KEGG   Homo sapiens (human): 84433
Entry
84433             CDS       T01001                                 

Gene name
CARD11, BENTA, BIMP3, CARMA1, IMD11, IMD11A, PPBL
Definition
(RefSeq) caspase recruitment domain family member 11
  KO
K07367  caspase recruitment domain-containing protein 11
Organism
hsa  Homo sapiens (human)
Pathway
hsa04064  NF-kappa B signaling pathway
hsa04660  T cell receptor signaling pathway
hsa04662  B cell receptor signaling pathway
Disease
H00093  Combined immunodeficiency
H02424  Primary central nervous system lymphoma
H02434  Diffuse large B-cell lymphoma, not otherwise specified
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    84433 (CARD11)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    84433 (CARD11)
   04662 B cell receptor signaling pathway
    84433 (CARD11)
SSDB
Motif
Pfam: CARD PDZ Guanylate_kin PDZ_6
Other DBs
NCBI-GeneID: 84433
NCBI-ProteinID: NP_001311210
OMIM: 607210
HGNC: 16393
Ensembl: ENSG00000198286
Vega: OTTHUMG00000023023
Pharos: Q9BXL7(Tbio)
UniProt: Q9BXL7 A0A024R854 Q8TES3
Structure
PDB: 
4LWD 4JUP

Position
7p22.2
AA seq 1154 aa
MPGGGPEMDDYMETLKDEEDALWENVECNRHMLSRYINPAKLTPYLRQCKVIDEQDEDEV
LNAPMLPSKINRAGRLLDILHTKGQRGYVVFLESLEFYYPELYKLVTGKEPTRRFSTIVV
EEGHEGLTHFLMNEVIKLQQQMKAKDLQRCELLARLRQLEDEKKQMTLTRVELLTFQERY
YKMKEERDSYNDELVKVKDDNYNLAMRYAQLSEEKNMAVMRSRDLQLEIDQLKHRLNKME
EECKLERNQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGKRSLPDSDKA
ILDILEHDRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKDCEM
YKHRMNTVMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEMRIE
MVRREACIVNLESKLRRLSKDSNNLDQSLPRNLPVTIISQDFGDASPRTNGQEADDSSTS
EESPEDSKYFLPYHPPQRRMNLKGIQLQRAKSPISLKRTSDFQAKGHEEEGTDASPSSCG
SLPITNSFTKMQPPRSRSSIMSITAEPPGNDSIVRRYKEDAPHRSTVEEDNDSGGFDALD
LDDDSHERYSFGPSSIHSSSSSHQSEGLDAYDLEQVNLMFRKFSLERPFRPSVTSVGHVR
GPGPSVQHTTLNGDSLTSQLTLLGGNARGSFVHSVKPGSLAEKAGLREGHQLLLLEGCIR
GERQSVPLDTCTKEEAHWTIQRCSGPVTLHYKVNHEGYRKLVKDMEDGLITSGDSFYIRL
NLNISSQLDACTMSLKCDDVVHVRDTMYQDRHEWLCARVDPFTDHDLDMGTIPSYSRAQQ
LLLVKLQRLMHRGSREEVDGTHHTLRALRNTLQPEEALSTSDPRVSPRLSRASFLFGQLL
QFVSRSENKYKRMNSNERVRIISGSPLGSLARSSLDATKLLTEKQEELDPESELGKNLSL
IPYSLVRAFYCERRRPVLFTPTVLAKTLVQRLLNSGGAMEFTICKSDIVTRDEFLRRQKT
ETIIYSREKNPNAFECIAPANIEAVAAKNKHCLLEAGIGCTRDLIKSNIYPIVLFIRVCE
KNIKRFRKLLPRPETEEEFLRVCRLKEKELEALPCLYATVEPDMWGSVEELLRVVKDKIG
EEQRKTIWVDEDQL
NT seq 3465 nt   +upstreamnt  +downstreamnt
atgccaggaggagggccagagatggatgactacatggagacgctgaaggatgaagaggac
gccttgtgggagaatgtggagtgtaaccggcacatgctcagccgctatatcaaccctgcc
aagctcacgccctacctgcgtcagtgtaaggtcattgatgagcaggatgaagatgaagtg
cttaatgcccctatgctgccatccaagatcaaccgagcaggccggctgttggacattcta
cataccaaggggcaaaggggctatgtggtcttcttggagagcctagaattttattaccca
gaactgtacaaactggtgactgggaaagagcccactcggagattctccaccattgtggtg
gaggaaggccacgagggcctcacgcacttcctgatgaacgaggtcatcaagctgcagcag
cagatgaaggccaaggacctgcaacgctgcgagctgctggccaggttgcggcagctggag
gatgagaagaagcagatgacgctgacgcgcgtggagctgctaaccttccaggagcggtac
tacaagatgaaggaagagcgggacagctacaatgacgagctggtcaaggtgaaggacgac
aactacaacttagccatgcgctacgcacagctcagtgaggagaagaacatggcggtcatg
aggagccgagacctccaactcgagatcgatcagctaaagcaccggttgaataagatggag
gaggaatgtaagctggagagaaatcagtctctaaaactgaagaatgacattgaaaatcgg
cccaagaaggagcaggttctggaactggagcgggagaatgaaatgctgaagaccaaaaac
caggagctgcagtccatcatccaggccgggaagcgcagcctgccagactcagacaaggcc
atcctggacatcttggaacacgaccgcaaggaggccctggaggacaggcaggagctggtc
aacaggatctacaacctgcaggaggaggcccgccaggcagaggagctgcgagacaagtac
ctggaggagaaggaggacctggagctcaagtgctcgaccctgggaaaggactgtgaaatg
tacaagcaccgcatgaacacggtcatgctgcagctggaggaggtggagcgggagcgggac
caggccttccactcccgagatgaagctcagacacagtactcgcagtgcttaatcgaaaag
gacaagtacaggaagcagatccgcgagctggaggagaagaacgacgagatgaggatcgag
atggtgcggcgggaggcctgcatcgtcaacctggagagcaagctgcggcgcctctccaag
gacagcaacaacctggaccagagtctgcccaggaacctgccagtaaccatcatctctcag
gactttggggatgccagccccaggaccaatggtcaagaagctgacgattcttccacctcg
gaggagtcacctgaagacagcaagtacttcctgccctaccatccgccccagcgcaggatg
aacctgaagggcatccagctgcagagagccaaatcccccatcagcctgaagcgaacatca
gattttcaagccaaggggcacgaggaagaaggcacggacgccagccctagctcctgcgga
tctctgcccatcaccaactccttcaccaagatgcagcccccccggagccgcagcagcatc
atgtcaatcaccgccgagcccccgggaaacgactccatcgtcagacgctacaaggaggac
gcgccccatcgcagcacagtcgaagaagacaatgacagcggcgggtttgacgccttagat
ctggatgatgacagtcacgaacgctactccttcggaccctcctccatccactcctcctcc
tcctcccaccaatccgagggcctggatgcctacgacctggagcaggtcaacctcatgttc
aggaagttctctctggaaagacccttccggccttcggtcacctctgtggggcacgtgcgg
ggcccagggccctcggtgcagcacacgacgctgaatggcgacagcctcacctcccagctc
accctgctggggggcaacgcgcgagggagcttcgtgcactcggtcaagcctggctctctg
gccgagaaagccggcctccgtgagggccaccagctgctgctgctagaaggctgcatccga
ggcgagaggcagagtgtcccgttggacacatgcaccaaagaggaagcccactggaccatc
cagaggtgcagcggccccgtcacgctgcactacaaggtcaaccacgaagggtaccggaag
ctggtgaaggacatggaggacggcctgatcacatcgggggactcgttctacatccggctg
aacctgaacatctccagccagctggacgcctgcaccatgtccctgaagtgtgacgatgtt
gtgcacgtccgtgacaccatgtaccaggacaggcacgagtggctgtgcgcgcgggtcgac
cctttcacagaccatgacctggatatgggcaccatacccagctacagccgagcccagcag
ctcctcctggtgaaactgcagcgcctgatgcaccgaggcagccgggaggaggtagacggc
acccaccacaccctgcgggcactccggaacaccctgcagccagaagaagcgctttcaaca
agcgacccccgggtcagcccccgtctctcgcgagcaagcttcctttttggccagctcctt
cagttcgtcagcaggtccgagaacaagtataagcggatgaacagcaacgagcgggtccgc
atcatctcggggagtccgctagggagcctggcccggtcctcgctggacgccaccaagctc
ttgactgagaagcaggaagagctggaccctgagagcgagctgggcaagaacctcagcctc
atcccctacagcctggtacgcgccttctactgcgagcgccgccggcccgtgctcttcaca
cccaccgtgctggccaagacgctggtgcagaggctgctcaactcgggaggtgccatggag
ttcaccatctgcaagtcagatatcgtcacaagagatgagttcctcagaaggcagaagacg
gagaccatcatctactcccgagagaagaaccccaacgcgttcgaatgcatcgcccctgcc
aacattgaagctgtggccgccaagaacaagcactgcctgctggaggctgggatcggctgc
acaagagacttgatcaagtccaacatctaccccatcgtgctcttcatccgggtgtgtgag
aagaacatcaagaggttcagaaagctgctgccccgacctgagacggaggaggagttcctg
cgcgtgtgccggctgaaggagaaggagctggaggccctgccgtgcctgtacgccacggtg
gaacctgacatgtggggcagcgtagaggagctgctccgcgttgtcaaggacaagatcggc
gaggagcagcgcaagaccatctgggtggacgaggaccagctgtga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (7)   
   KEGG DISEASE (3)   
   OMIM (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (65)   

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