KEGG   Homo sapiens (human): 84733
Entry
84733             CDS       T01001                                 
Symbol
CBX2, CDCA6, M33, SRXY5
Name
(RefSeq) chromobox 2
  KO
K11451  chromobox protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03083  Polycomb repressive complex
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01585  Deubiquitination of H2AK119
Disease
H00607  46,XY gonadal dysgenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    84733 (CBX2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    84733 (CBX2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Canonical PRC1 (PRC1.2/1.4)
     84733 (CBX2)
SSDB
Motif
Pfam: Chromo CBX7_C AF-4 PI3K_1B_p101 MSL3_chromo-like Tudor-knot
Other DBs
NCBI-GeneID: 84733
NCBI-ProteinID: NP_005180
OMIM: 602770
HGNC: 1552
Ensembl: ENSG00000173894
UniProt: Q14781
Structure
Position
17:79777311..79787983
AA seq 532 aa
MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK
KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS
DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV
SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG
MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG
MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS
VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA
PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG
QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY
NT seq 1599 nt   +upstreamnt  +downstreamnt
atggaggagctgagcagcgtgggcgagcaggtcttcgccgccgagtgcatcctgagcaag
cggctccgcaagggcaagctggagtacctggtcaagtggcgcggctggtcctccaaacat
aacagctgggagccggaggagaacatcctggacccgaggctgctcctggccttccagaag
aaggaacatgagaaggaggtgcagaaccggaagagaggcaagaggccgagaggccggcca
aggaagctcactgccatgtcctcctgcagccggcgctccaagctcaaggaacccgatgct
ccctccaaatccaagtccagcagttcctcctcttcctccacgtcatcctcctcttcctca
gatgaagaggatgacagtgacttagatgctaagaggggtccccggggccgcgagacccac
ccagtgccgcagaagaaggcccagatcctggtggccaaacccgagctgaaggatcccatc
cggaagaagcggggacgaaagcccctgcccccagagcaaaaggcaacccgaagacccgtg
agcctggccaaggtgctgaagaccgcccggaaggatctgggggccccggccagcaagctg
ccccctccactcagcgcccccgttgcaggcctggcagctctgaaggcccacgccaaggag
gcctgtggcggccccagtgccatggccaccccagagaacctggccagcctaatgaagggc
atggccagtagccccggccggggtggcatcagctggcagagctccatcgtgcactacatg
aaccggatgacccagagccaggcccaggctgccagcaggttggcgctgaaggcccaggcc
accaacaagtgcggcctcgggctggacctgaaggtgaggacgcagaaaggggagctggga
atgagccctccaggaagcaaaatcccgaaggcccccagcggtggggctgtggagcagaaa
gtggggaacacagggggccccccgcacacccatggtgccagcagggtgcctgctgggtgc
ccaggcccccagccagcacccacccaggagctgagcctccaggtcttggacttgcagagt
gtcaagaatggcatgcccggggtgggtctccttgcccgccacgccaccgccaccaagggt
gtcccggccaccaacccagcccctgggaagggcactgggagtggcctcattggggccagc
ggggccaccatgcccaccgacacaagcaaaagtgagaagctggcttccagagcagtggcg
ccacccacccctgccagcaagagggactgtgtcaagggcagtgctacccccagtgggcag
gagagccgcacagcccccggagaagcccgcaaggcggccacactgccagagatgagcgca
ggtgaggagagtagcagctcggactccgaccccgactccgcctcgccgcccagcactgga
cagaacccgtcagtgtccgttcagaccagccaggactggaagcccacccgcagcctcatc
gagcacgtatttgtcaccgacgtcactgccaacctcatcaccgtcacagtgaaggagtct
cccaccagcgtgggcttcttcaacctgaggcattactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (3)   
   KEGG NETWORK (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (28)   
   RefSeq(nuc) (8)   
   GenBank (10)   
   EMBL (10)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (82)   

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