KEGG   Homo sapiens (human): 84790
Entry
84790             CDS       T01001                                 

Gene name
TUBA1C, TUBA6, bcm948
Definition
(RefSeq) tubulin alpha 1c
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04210  Apoptosis
hsa04530  Tight junction
hsa04540  Gap junction
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06419  Microtubule-based transport
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    84790 (TUBA1C)
  09143 Cell growth and death
   04210 Apoptosis
    84790 (TUBA1C)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    84790 (TUBA1C)
   04540 Gap junction
    84790 (TUBA1C)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    84790 (TUBA1C)
   05012 Parkinson disease
    84790 (TUBA1C)
   05014 Amyotrophic lateral sclerosis
    84790 (TUBA1C)
   05016 Huntington disease
    84790 (TUBA1C)
   05020 Prion disease
    84790 (TUBA1C)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    84790 (TUBA1C)
   05132 Salmonella infection
    84790 (TUBA1C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    84790 (TUBA1C)
   03036 Chromosome and associated proteins [BR:hsa03036]
    84790 (TUBA1C)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    84790 (TUBA1C)
   04147 Exosome [BR:hsa04147]
    84790 (TUBA1C)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     84790 (TUBA1C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Microtubules and associated factors
    Other tubulins
     84790 (TUBA1C)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    84790 (TUBA1C)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   84790 (TUBA1C)
  Exosomal proteins of other body fluids (saliva and urine)
   84790 (TUBA1C)
  Exosomal proteins of colorectal cancer cells
   84790 (TUBA1C)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3
Other DBs
NCBI-GeneID: 84790
NCBI-ProteinID: NP_116093
HGNC: 20768
Ensembl: ENSG00000167553
Vega: OTTHUMG00000169497
Pharos: Q9BQE3(Tchem)
UniProt: Q9BQE3
Position
12q13.12
AA seq 449 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGADSADGEDEGEEY
NT seq 1350 nt   +upstreamnt  +downstreamnt
atgcgtgagtgcatctccatccacgttggccaggctggtgtccagattggcaatgcctgc
tgggagctctactgcctggaacacggcatccagcccgatggccagatgccaagtgacaag
accattgggggaggagatgattccttcaacaccttcttcagtgaaacgggtgctggcaag
catgtgccccgggcagtgtttgtagacttggaacccacagtcattgatgaagttcgcact
ggcacttaccgccagctcttccaccctgagcaactcatcacaggcaaggaagatgctgcc
aataactatgcccgagggcactacaccattggcaaggagatcattgacctcgtgttggac
cgaattcgcaagctggctgaccagtgcaccggtcttcagggcttcttggttttccacagc
tttggtgggggaactggttctgggttcacctcgctgctcatggaacgtctctcagttgat
tatggcaagaagtccaagctggagttctccatttacccggcgccccaggtttccacagct
gtagttgagccctacaactccatcctcaccacccacaccaccctggagcactctgattgt
gccttcatggtagacaatgaggccatctatgacatctgtcgtagaaacctcgatatcgag
cgcccaacctacactaaccttaaccgccttattagccagattgtgtcctccatcactgct
tccctgagatttgatggagccctgaatgttgacctgacagaattccagaccaacctggtg
ccctacccccgcatccacttccctctggccacatatgcccctgtcatctctgctgagaaa
gcctaccacgaacagcttactgtagcagagatcaccaatgcttgctttgagccagccaac
cagatggtgaaatgtgaccctcgccatggtaaatacatggcttgctgcctgttataccgt
ggtgacgtggttcccaaagatgtcaatgctgccattgccaccatcaaaaccaagcgtacc
atccagtttgtggattggtgccccactggcttcaaggttggcattaattaccagcctccc
actgtggtgcctggcggagacctggccaaggtacagagagctgtgtgcatgctgagcaat
accacagctgttgccgaggcctgggctcgcctggaccacaagtttgacctgatgtatgcc
aagcgtgcctttgttcactggtacgtgggtgaggggatggaggaaggcgagttttcagag
gcccgtgaggacatggctgcccttgagaaggattatgaggaggttggagcagatagtgct
gacggagaggatgagggtgaagagtattaa

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