KEGG   Homo sapiens (human): 84868
Entry
84868             CDS       T01001                                 

Gene name
HAVCR2, CD366, HAVcr-2, KIM-3, SPTCL, TIM3, TIMD-3, TIMD3, Tim-3
Definition
(RefSeq) hepatitis A virus cellular receptor 2
  KO
K20414  hepatitis A virus cellular receptor 2
Organism
hsa  Homo sapiens (human)
Drug target
Cobolimab: D11377
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    84868 (HAVCR2)
CD molecules [BR:hsa04090]
 Proteins
  84868 (HAVCR2)
SSDB
Motif
Pfam: V-set ig Ig_2 I-set Ig_3 Receptor_2B4
Other DBs
NCBI-GeneID: 84868
NCBI-ProteinID: NP_116171
OMIM: 606652
HGNC: 18437
Ensembl: ENSG00000135077
Vega: OTTHUMG00000130249
Pharos: Q8TDQ0(Tbio)
UniProt: Q8TDQ0
Structure
PDB: 
6DHB 5F71

Position
5q33.3
AA seq 301 aa
MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPV
FECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMND
EKFNLKLVIKPAKVTPAPTRQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLA
NELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNLSLI
SLANLPPSGLANAVAEGIRSEENIYTIEENVYEVEEPNEYYCYVSSRQQPSQPLGCRFAM
P
NT seq 906 nt   +upstreamnt  +downstreamnt
atgttttcacatcttccctttgactgtgtcctgctgctgctgctgctactacttacaagg
tcctcagaagtggaatacagagcggaggtcggtcagaatgcctatctgccctgcttctac
accccagccgccccagggaacctcgtgcccgtctgctggggcaaaggagcctgtcctgtg
tttgaatgtggcaacgtggtgctcaggactgatgaaagggatgtgaattattggacatcc
agatactggctaaatggggatttccgcaaaggagatgtgtccctgaccatagagaatgtg
actctagcagacagtgggatctactgctgccggatccaaatcccaggcataatgaatgat
gaaaaatttaacctgaagttggtcatcaaaccagccaaggtcacccctgcaccgactcgg
cagagagacttcactgcagcctttccaaggatgcttaccaccaggggacatggcccagca
gagacacagacactggggagcctccctgatataaatctaacacaaatatccacattggcc
aatgagttacgggactctagattggccaatgacttacgggactctggagcaaccatcaga
ataggcatctacatcggagcagggatctgtgctgggctggctctggctcttatcttcggc
gctttaattttcaaatggtattctcatagcaaagagaagatacagaatttaagcctcatc
tctttggccaacctccctccctcaggattggcaaatgcagtagcagagggaattcgctca
gaagaaaacatctataccattgaagagaacgtatatgaagtggaggagcccaatgagtat
tattgctatgtcagcagcaggcagcaaccctcacaacctttgggttgtcgctttgcaatg
ccatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (2)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
Protein domain (6)   
   Pfam (6)   
All databases (57)   

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