| Entry |
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| Symbol |
POMGNT2, AGO61, C3orf39, GTDC2, MDDGA8, MDDGC8
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| Name |
(RefSeq) protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
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| KO |
| K18207 | protein O-mannose beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.312] |
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| Organism |
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| Pathway |
| hsa00515 | Mannose type O-glycan biosynthesis |
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| Module |
| hsa_M00872 | O-glycan biosynthesis, mannose type (core M3) |
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| Network |
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| Element |
| N00627 | Mannose type O-glycan biosynthesis, POMT to POMK |
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| Disease |
| H00120 | Muscular dystrophy-dystroglycanopathy type A |
| H00593 | Limb-girdle muscular dystrophy |
| H01959 | Muscular dystrophy-dystroglycanopathy type C |
| H02307 | Muscular dystrophy-dystroglycanopathy |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00515 Mannose type O-glycan biosynthesis
84892 (POMGNT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:hsa01003]
84892 (POMGNT2)
Enzymes [BR:hsa01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.312 protein O-mannose beta-1,4-N-acetylglucosaminyltransferase
84892 (POMGNT2)
Glycosyltransferases [BR:hsa01003]
Glycan extension
O-Glycan
84892 (POMGNT2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
3:complement(43079234..43106079)
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| AA seq |
580 aa
MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT |
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| NT seq |
1743 nt +upstreamnt +downstreamnt
atgcacctctcggcggtgttcaacgccctcctggtgtcggtgctggcagcggtcctgtgg
aagcatgtgcggctgcgtgagcatgcagccacactggaggaggagctggccctcagccga
caggccacagagccagccccagcactgaggatcgactacccgaaggcactgcagatcctg
atggagggcggcacacacatggtgtgcacgggccgcacgcacacagaccgcatctgccgc
ttcaagtggctctgctactccaacgaggctgaggagttcatcttcttccatggcaacacc
tctgtcatgctgcccaacctgggctcccggcgcttccagccagccctgctcgacctatcc
accgtggaggaccacaacactcagtacttcaacttcgtggagctgcctgctgctgccctg
cgcttcatgcccaagccggtgttcgtgccagacgtggccctcatcgccaaccgcttcaac
cccgacaacctcatgcacgtctttcatgacgacctgctgccactcttctacaccctgcgg
cagtttcccggcctggcccacgaggcacggctcttcttcatggagggctggggcgagggt
gcacacttcgacctctacaagctgctcagccccaagcagcctctcctgcgggcacagctg
aagaccctgggccggctgctgtgcttctcccatgcttttgtgggcctctccaagatcact
acctggtaccagtatggctttgtgcagccccagggcccgaaggccaacatcctcgtctca
ggcaatgagatccggcagtttgcacggttcatgacagaaaagctgaacgtgagccacaca
ggagtccccctaggcgaggagtacattctggtctttagccgaacccagaacagactcatt
ctgaatgaggcagagctgctgctggcactggcccaggagttccagatgaagacagtgaca
gtgtccctggaggaccacacctttgctgatgtcgtgcggctggtcagcaatgcctccatg
ctggtcagcatgcatggggcccagctggtcaccaccctcttcctgccccgtggggcaact
gtggtagagctcttcccatatgctgtcaatcccgaccactacactccctataagacgctg
gccatgctgcctggcatggacctccagtatgtagcctggcggaacatgatgccagagaac
acagtcacacaccctgagcggccctgggatcaggggggcatcacccatctggaccgggct
gagcaagcccgtatcctgcaaagccgtgaggtcccacggcatctctgttgccggaacccc
gagtggctcttccgaatctaccaggacaccaaggtggacatcccgtccctcattcaaacc
atacggcgcgtggtgaagggccggccaggaccacggaagcagaagtggacagtcggccta
tatccaggcaaggtgcgggaggcacggtgccaggcgtcagtgcatggcgcctccgaggcc
cgcctcactgtctcctggcagatcccatggaaccttaaatacctgaaggtgagggaggtg
aagtacgaggtgtggctgcaggagcagggggagaacacctacgtgccttacatcctggct
ctgcagaaccacaccttcactgagaacatcaagcccttcaccacctacctggtgtgggtc
cgctgcatcttcaacaagatcctcctgggaccctttgcagatgtgctggtgtgcaacacg
tag |
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