KEGG   Homo sapiens (human): 8515
Entry
8515              CDS       T01001                                 
Symbol
ITGA10, PRO827
Name
(RefSeq) integrin subunit alpha 10
  KO
K06586  integrin alpha 10
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04810  Regulation of actin cytoskeleton
hsa04820  Cytoskeleton in muscle cells
hsa05165  Human papillomavirus infection
hsa05410  Hypertrophic cardiomyopathy
hsa05412  Arrhythmogenic right ventricular cardiomyopathy
hsa05414  Dilated cardiomyopathy
Network
nt06167  Human cytomegalovirus (HCMV)
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06183  Yersinia
  Element
N00393  ITGA/B-RhoGAP-RhoA signaling pathway
N00951  ITGA/B-RHOG-RAC signaling pathway
N01068  ITGA/B-FAK-RAC signaling pathway
N01070  ITGA/B-FAK-CDC42 signaling pathway
N01072  ITGA/B-RhoGEF-RhoA signaling pathway
N01080  ITGA/B-TALIN/VINCULIN signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    8515 (ITGA10)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    8515 (ITGA10)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    8515 (ITGA10)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    8515 (ITGA10)
   04810 Regulation of actin cytoskeleton
    8515 (ITGA10)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    8515 (ITGA10)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    8515 (ITGA10)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    8515 (ITGA10)
   05414 Dilated cardiomyopathy
    8515 (ITGA10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    8515 (ITGA10)
Cell adhesion molecules [BR:hsa04515]
 Integrins
  Integrin alpha subunits
   8515 (ITGA10)
SSDB
Motif
Pfam: VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_1 VWA_2 FG-GAP_3 Integrin_A_Ig_3 ITGAX-like_Ig_3 FG-GAP_2
Other DBs
NCBI-GeneID: 8515
NCBI-ProteinID: NP_003628
OMIM: 604042
HGNC: 6135
Ensembl: ENSG00000143127
UniProt: O75578
Position
1:complement(145891208..145910050)
AA seq 1167 aa
MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGA
PWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGG
FMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYP
WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREG
RETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRY
GIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGS
HAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEF
PPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGE
QIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQ
PEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIA
AASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAIS
VVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQ
RLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQ
KLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNT
SLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSC
SSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTL
PVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLT
EPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFK
SLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALL
VFCLWKLGFFAHKKIPEEEKREEKLEQ
NT seq 3504 nt   +upstreamnt  +downstreamnt
atggaactccccttcgtcactcacctgttcttgcccctggtgttcctgacaggtctctgc
tccccctttaacctggatgaacatcacccacgcctattcccagggccaccagaagctgaa
tttggatacagtgtcttacaacatgttgggggtggacagcgatggatgctggtgggcgcc
ccctgggatgggccttcaggcgaccggaggggggacgtttatcgctgccctgtagggggg
gcccacaatgccccatgtgccaagggccacttaggtgactaccaactgggaaattcatct
catcctgctgtgaatatgcacctggggatgtctctgttagagacagatggtgatggggga
ttcatggcctgtgcccctctctggtctcgtgcttgtggcagctctgtcttcagttctggg
atatgtgcccgtgtggatgcttcattccagcctcagggaagcctggcacccactgcccaa
cgctgcccaacatacatggatgttgtcattgtcttggatggctccaacagcatctacccc
tggtctgaagttcagaccttcctacgaagactggtagggaaactgtttattgacccagaa
cagatacaggtgggactggtacagtatggggagagccctgtacatgagtggtccctggga
gatttccgaacgaaggaagaagtggtgagagcagcaaagaacctcagtcggcgggaggga
cgagaaacaaagactgcccaagcaataatggtggcctgcacagaagggttcagtcagtcc
catgggggccgacccgaggctgccaggctactggtggttgtcactgatggagagtcccat
gatggagaggagcttcctgcagcactaaaggcctgtgaggctggaagagtgacacgctat
gggattgcagtccttggtcactacctccggcggcagcgagatcccagctctttcctgaga
gaaattagaactattgccagtgatccagatgagcgattcttcttcaatgtcacagatgag
gctgctctgactgacattgtggatgcactaggagatcggatttttggccttgaagggtcc
catgcagaaaacgaaagctcctttgggctggaaatgtctcagattggtttctccactcat
cggctaaaggatgggattctttttgggatggtgggggcctatgactggggaggctctgtg
ctatggcttgaaggaggccaccgccttttccccccacgaatggcactggaagacgagttc
ccccctgcattgcagaaccatgcagcctacctgggttactctgtttcttccatgcttttg
cggggtggacgccgcctgtttctctctggggctcctcgatttagacatcgaggaaaagtc
atcgccttccagcttaagaaagatggggctgtgagggttgcccagagcctccagggggag
cagattggttcatactttggcagtgagctctgcccattggatacagatagggatggaaca
actgatgtcttacttgtggctgcccccatgttcctgggaccccagaacaaggaaacagga
cgtgtttatgtgtatctggtaggccagcagtccttgctgaccctccaaggaacacttcag
ccagaacccccccaggatgctcggtttggctttgccatgggagctcttcctgatctgaac
caagatggttttgctgatgtggctgtgggggcgcctctggaagatgggcaccagggagca
ctgtacctgtaccatggaacccagagtggagtcaggccccatcctgcccagaggattgct
gctgcctccatgccacatgccctcagctactttggccgaagtgtggatggtcggctagat
ctggatggagatgatctggtcgatgtggctgtgggtgcccagggggcagccatcctgctc
agctcccggcccattgtccatctgaccccatcactggaggtgaccccacaggccatcagt
gtggttcagagggactgtaggcggcgaggccaagaggcagtctgtctgactgcagccctt
tgcttccaagtgacctcccgtactcctggtcgctgggatcaccaattctacatgaggttc
accgcatcactggatgaatggactgctggggcacgtgcagcatttgatggctctggccag
aggttgtcccctcggaggctccggctcagtgtggggaatgtcacttgtgagcagctacac
ttccatgtgctggatacatcagattacctccggccagtggccttgactgtgacctttgcc
ttggacaatactacaaagccagggcctgtgctgaatgagggctcacccacctctatacaa
aagctggtccccttctcaaaggattgtggccctgacaatgaatgtgtcacagacctggtg
cttcaagtgaatatggacatcagaggctccaggaaggccccatttgtggttcgaggtggc
cggcggaaagtgctggtatctacaactctggagaacagaaaggaaaatgcttacaatacg
agcctgagtctcatcttctctagaaacctccacctggccagtctcactcctcagagagag
agcccaataaaggtggaatgtgccgccccttctgctcatgcccggctctgcagtgtgggg
catcctgtcttccagactggagccaaggtgacctttctgctagagtttgagtttagctgc
tcctctctcctgagccaggtcttcgtgaagctgactgccagcagtgacagcctggagaga
aatgggacccttcaagataacacagcccagacctcagcctacatccaatatgagccccac
ctcctgttctctagtgagtctaccctgcaccgctatgaggttcacccatatgggaccctc
ccagtgggtcctggcccagaattcaaaaccactctcagggttcagaacctaggctgctat
gtggtcagtggcctcatcatctcagccctccttccagctgtggcccatgggggcaattac
ttcctatcactgtctcaagtcatcactaacaatgcaagctgcatagtgcagaacctgact
gaacccccaggcccacctgtgcatccagaggagcttcaacacacaaacagactgaatggg
agcaatactcagtgtcaggtggtgaggtgccaccttgggcagctggcaaaggggactgag
gtctctgttggactattgaggctggttcacaatgaatttttccgaagagccaagttcaag
tccctgacggtggtcagcacctttgagctgggaaccgaagagggcagtgtcctacagctg
actgaagcctcccgttggagtgagagcctcttggaggtggttcagacccggcctatcctc
atctccctgtggatcctcataggcagtgtcctgggagggttgctcctgcttgctctcctt
gtcttctgcctgtggaagcttggcttctttgcccataagaaaatccctgaggaagaaaaa
agagaagagaagttggagcaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Network (11)   
   KEGG NETWORK (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (35)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (33)   
DNA sequence (57)   
   RefSeq(nuc) (37)   
   GenBank (10)   
   EMBL (10)   
Protein domain (9)   
   Pfam (9)   
All databases (139)   

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