| Entry |
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| Symbol |
ALG2, CDG1I, CDGIi, CMS14, CMSTA3, NET38, hALPG2
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| Name |
(RefSeq) ALG2 alpha-1,3/1,6-mannosyltransferase
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| KO |
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| Organism |
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| Pathway |
| hsa00513 | Various types of N-glycan biosynthesis |
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| Module |
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| Network |
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| Element |
| N00653 | N-Glycan precursor biosynthesis, ALG7 to ALG11 |
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| Disease |
| H00118 | Congenital disorders of glycosylation type I |
| H00770 | Congenital myasthenic syndrome |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00510 N-Glycan biosynthesis
85365 (ALG2)
00513 Various types of N-glycan biosynthesis
85365 (ALG2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:hsa01003]
85365 (ALG2)
Enzymes [BR:hsa01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.132 GDP-Man:Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase
85365 (ALG2)
2.4.1.257 GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
85365 (ALG2)
Glycosyltransferases [BR:hsa01003]
N-Glycan biosynthesis
Dol-linked oligosaccharide
85365 (ALG2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
9:complement(99216425..99221942)
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| AA seq |
416 aa
MAEEQGRERDSVPKPSVLFLHPDLGVGGAERLVLDAALALQARGCSVKIWTAHYDPGHCF
AESRELPVRCAGDWLPRGLGWGGRGAAVCAYVRMVFLALYVLFLADEEFDVVVCDQVSAC
IPVFRLARRRKKILFYCHFPDLLLTKRDSFLKRLYRAPIDWIEEYTTGMADCILVNSQFT
AAVFKETFKSLSHIDPDVLYPSLNVTSFDSVVPEKLDDLVPKGKKFLLLSINRYERKKNL
TLALEALVQLRGRLTSQDWERVHLIVAGGYDERVLENVEHYQELKKMVQQSDLGQYVTFL
RSFSDKQKISLLHSCTCVLYTPSNEHFGIVPLEAMYMQCPVIAVNSGGPLESIDHSVTGF
LCEPDPVHFSEAIEKFIREPSLKATMGLAGRARVKEKFSPEAFTEQLYRYVTKLLV |
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| NT seq |
1251 nt +upstreamnt +downstreamnt
atggcggaggagcagggccgggaacgggactcggttcccaagccgtcggtgctgttcctc
cacccagacctgggcgtgggcggcgctgagcggctggtgttggacgcggcgctggcgctg
caggcgcgcgggtgtagcgtgaagatctggacagcgcactacgacccgggccactgtttc
gccgagagccgcgagctaccggtgcgctgtgccggggactggctgccgcgaggcctgggc
tggggcggccgcggcgccgccgtctgcgcctacgtgcgcatggttttcctggcgctctac
gtgctgttcctcgccgacgaggagttcgacgtggtagtgtgcgaccaggtgtctgcctgt
atcccagtgttcaggctggctagacggcggaagaagatcctattttactgtcacttccca
gatctgcttctcaccaagagagattcttttcttaaacgactatacagggccccaattgac
tggatagaggaatacaccacaggcatggcagactgcatcttagtcaacagccagttcaca
gctgctgtttttaaggaaacattcaagtccctgtctcacatagaccctgatgtcctctat
ccatctctaaatgtcaccagctttgactcagttgttcctgaaaagctggatgacctagtc
cccaaggggaaaaaattcctgctgctctccatcaacagatacgaaaggaagaaaaatctg
actttggcactggaagccctagtacagctgcgtggaagattgacatcccaagattgggag
agggttcatctgatcgtggcaggtggttatgacgagagagtcctggagaatgtggaacat
tatcaggaattgaagaaaatggtccaacagtccgaccttggccagtatgtgaccttcttg
aggtctttctcagacaaacagaaaatctccctcctccacagctgcacgtgtgtgctttac
acaccaagcaatgagcactttggcattgtccctctggaagccatgtacatgcagtgccca
gtcattgctgttaattcgggtggacccttggagtccattgaccacagtgtcacagggttt
ctgtgtgagcctgacccggtgcacttctcagaagcaatagaaaagttcatccgtgaacct
tccttaaaagccaccatgggcctggctggaagagccagagtgaaggaaaaattttcccct
gaagcatttacagaacagctctaccgatatgttaccaaactgctggtataa |
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