KEGG   Homo sapiens (human): 8550
Entry
8550              CDS       T01001                                 
Symbol
MAPKAPK5, MAPKAP-K5, MK-5, MK5, NCFD, PRAK
Name
(RefSeq) MAPK activated protein kinase 5
  KO
K04442  mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Disease
H02763  Neurocardiofaciodigital syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    8550 (MAPKAPK5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8550 (MAPKAPK5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8550 (MAPKAPK5)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  MAPKAPK family [OT]
   8550 (MAPKAPK5)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo Kinase-like
Other DBs
NCBI-GeneID: 8550
NCBI-ProteinID: NP_620777
OMIM: 606723
HGNC: 6889
Ensembl: ENSG00000089022
UniProt: Q8IW41
Position
12:111842228..111902222
AA seq 473 aa
MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKAR
NEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHF
TEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGDL
MTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPP
FYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLD
HPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPIL
RKRKLLGTKPKDSVYIHDHENGAEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQ
EAWKYNRECKLLRDTLQSFSWNGRGFTDKVDRLKLAEIVKQVIEEQTTSHESQ
NT seq 1422 nt   +upstreamnt  +downstreamnt
atgtcggaggagagcgacatggacaaagccatcaaggaaacttccattttagaagaatac
agtatcaattggactcagaagctgggagctggaattagtggtccagttagagtctgtgta
aagaaatctactcaagaacggtttgcgctgaaaattcttcttgatcgtccaaaagctaga
aatgaggtacgtctgcacatgatgtgtgccacacacccaaacatagttcagattattgaa
gtgtttgctaacagtgtccagtttccccatgagtccagccctagggcccgactcttaatt
gtaatggagatgatggaagggggagagctatttcacagaatcagccagcaccggcacttt
acagagaagcaagccagccaagtaacaaagcagatagctttggctctgcggcactgtcac
ttgttaaacattgcgcacagagacctcaagcctgaaaatctgctttttaaggataactct
ttggatgccccagtgaagttgtgtgactttggatttgccaagattgaccaaggtgacttg
atgacaccccagttcaccccttattatgtagcaccccaggtactggaggcgcaaagaagg
catcagaaggagaaatctggcatcatacctacctcaccgacgccctacacttacaacaag
agctgtgacttgtggtccctaggggtgattatctatgtgatgctgtgcggataccctcct
ttttactccaaacaccacagccggactatcccaaaggatatgcgaagaaagatcatgaca
ggcagttttgagttcccagaggaagagtggagtcagatctcagagatggccaaagatgtt
gtgaggaagctcctgaaggtcaaaccggaggagagactcaccatcgagggagtgctggac
cacccctggctcaattccaccgaggccctggataatgtgctgccttctgctcagctgatg
atggacaaggcagtggttgcaggaatccagcaggctcacgcggaacagttggccaacatg
agaatccaggatctgaaagtcagcctcaaacccctgcactcagtgaacaaccccattctg
cggaagaggaagttacttggcaccaagccaaaggacagtgtctatatccacgaccatgag
aatggagccgaggattccaatgttgccttggaaaaactccgagatgtgattgctcagtgt
attctcccccaggctggtaaaggagagaatgaagatgagaaactgaatgaagtaatgcag
gaggcttggaagtataaccgggaatgcaaactcctaagagatactctgcagagcttcagc
tggaatggtcgtggattcacagataaagtagatcgactaaaactggcagaaattgtgaag
caggtgatagaagagcaaaccacgtcccacgaatcccaataa

  All links  
Disease (2)   
   OMIM (2)   
Gene (17)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (25)   
   RefSeq(nuc) (11)   
   GenBank (7)   
   EMBL (7)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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