KEGG   Homo sapiens (human): 8550Help
Entry
8550              CDS       T01001                                 

Gene name
MAPKAPK5, MAPKAP-K5, MK-5, MK5, PRAK
Definition
(RefSeq) MAPK activated protein kinase 5
  KO
K04442  mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    8550 (MAPKAPK5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8550 (MAPKAPK5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8550 (MAPKAPK5)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  MAPKAPK family [OT]
   8550 (MAPKAPK5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo Kinase-like
Motif
Other DBs
NCBI-GeneID: 8550
NCBI-ProteinID: NP_620777
OMIM: 606723
HGNC: 6889
Ensembl: ENSG00000089022
Vega: OTTHUMG00000169605
Pharos: Q8IW41(Tchem)
UniProt: Q8IW41
Position
12q24.12-q24.13
AA seq 473 aa AA seqDB search
MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKAR
NEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHF
TEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGDL
MTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPP
FYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLD
HPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPIL
RKRKLLGTKPKDSVYIHDHENGAEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQ
EAWKYNRECKLLRDTLQSFSWNGRGFTDKVDRLKLAEIVKQVIEEQTTSHESQ
NT seq 1422 nt NT seq  +upstreamnt  +downstreamnt
atgtcggaggagagcgacatggacaaagccatcaaggaaacttccattttagaagaatac
agtatcaattggactcagaagctgggagctggaattagtggtccagttagagtctgtgta
aagaaatctactcaagaacggtttgcgctgaaaattcttcttgatcgtccaaaagctaga
aatgaggtacgtctgcacatgatgtgtgccacacacccaaacatagttcagattattgaa
gtgtttgctaacagtgtccagtttccccatgagtccagccctagggcccgactcttaatt
gtaatggagatgatggaagggggagagctatttcacagaatcagccagcaccggcacttt
acagagaagcaagccagccaagtaacaaagcagatagctttggctctgcggcactgtcac
ttgttaaacattgcgcacagagacctcaagcctgaaaatctgctttttaaggataactct
ttggatgccccagtgaagttgtgtgactttggatttgccaagattgaccaaggtgacttg
atgacaccccagttcaccccttattatgtagcaccccaggtactggaggcgcaaagaagg
catcagaaggagaaatctggcatcatacctacctcaccgacgccctacacttacaacaag
agctgtgacttgtggtccctaggggtgattatctatgtgatgctgtgcggataccctcct
ttttactccaaacaccacagccggactatcccaaaggatatgcgaagaaagatcatgaca
ggcagttttgagttcccagaggaagagtggagtcagatctcagagatggccaaagatgtt
gtgaggaagctcctgaaggtcaaaccggaggagagactcaccatcgagggagtgctggac
cacccctggctcaattccaccgaggccctggataatgtgctgccttctgctcagctgatg
atggacaaggcagtggttgcaggaatccagcaggctcacgcggaacagttggccaacatg
agaatccaggatctgaaagtcagcctcaaacccctgcactcagtgaacaaccccattctg
cggaagaggaagttacttggcaccaagccaaaggacagtgtctatatccacgaccatgag
aatggagccgaggattccaatgttgccttggaaaaactccgagatgtgattgctcagtgt
attctcccccaggctggtaaaggagagaatgaagatgagaaactgaatgaagtaatgcag
gaggcttggaagtataaccgggaatgcaaactcctaagagatactctgcagagcttcagc
tggaatggtcgtggattcacagataaagtagatcgactaaaactggcagaaattgtgaag
caggtgatagaagagcaaaccacgtcccacgaatcccaataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (25)   
   RefSeq(nuc) (11)   
   GenBank (7)   
   EMBL (7)   
Protein domain (4)   
   Pfam (4)   
All databases (69)   

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