| Entry |
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| Symbol |
RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
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| Name |
(RefSeq) RUNX family transcription factor 2
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| KO |
| K09278 | runt-related transcription factor 2 |
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| Organism |
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| Pathway |
| hsa04928 | Parathyroid hormone synthesis, secretion and action |
| hsa05202 | Transcriptional misregulation in cancer |
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| Network |
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| Element |
| N00119 | MLL-AF4 fusion to transcriptional activation |
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| Disease |
| H00521 | Cleidocranial dysplasia |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
860 (RUNX2)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
860 (RUNX2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:hsa03000]
860 (RUNX2)
Transcription factors [BR:hsa03000]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
Runt
860 (RUNX2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
6:45328330..45551082
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| AA seq |
521 aa
MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN
FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA
RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS
LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD
QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKS
QAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHT
YLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGS
TLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY |
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| NT seq |
1566 nt +upstreamnt +downstreamnt
atggcatcaaacagcctcttcagcacagtgacaccatgtcagcaaaacttcttttgggat
ccgagcaccagccggcgcttcagccccccctccagcagcctgcagcccggcaaaatgagc
gacgtgagcccggtggtggctgcgcaacagcagcagcaacagcagcagcagcaacagcag
cagcagcagcagcaacagcagcagcagcagcaggaggcggcggcggcggctgcggcggcg
gcggcggctgcggcggcggcagctgcagtgccccggttgcggccgccccacgacaaccgc
accatggtggagatcatcgccgaccacccggccgaactcgtccgcaccgacagccccaac
ttcctgtgctcggtgctgccctcgcactggcgctgcaacaagaccctgcccgtggccttc
aaggtggtagccctcggagaggtaccagatgggactgtggttactgtcatggcgggtaac
gatgaaaattattctgctgagctccggaatgcctctgctgttatgaaaaaccaagtagca
aggttcaacgatctgagatttgtgggccggagtggacgaggcaagagtttcaccttgacc
ataaccgtcttcacaaatcctccccaagtagctacctatcacagagcaattaaagttaca
gtagatggacctcgggaacccagaaggcacagacagaagcttgatgactctaaacctagt
ttgttctctgaccgcctcagtgatttagggcgcattcctcatcccagtatgagagtaggt
gtcccgcctcagaacccacggccctccctgaactctgcaccaagtccttttaatccacaa
ggacagagtcagattacagaccccaggcaggcacagtcttccccgccgtggtcctatgac
cagtcttacccctcctacctgagccagatgacgtccccgtccatccactctaccaccccg
ctgtcttccacacggggcactgggcttcctgccatcaccgatgtgcctaggcgcatttca
gatgatgacactgccacctctgacttctgcctctggccttccactctcagtaagaagagc
caggcaggtgcttcagaactgggccctttttcagaccccaggcagttcccaagcatttca
tccctcactgagagccgcttctccaacccacgaatgcactatccagccacctttacttac
accccgccagtcacctcaggcatgtccctcggtatgtccgccaccactcactaccacacc
tacctgccaccaccctaccccggctcttcccaaagccagagtggacccttccagaccagc
agcactccatatctctactatggcacttcgtcaggatcctatcagtttcccatggtgccg
gggggagaccggtctccttccagaatgcttccgccatgcaccaccacctcgaatggcagc
acgctattaaatccaaatttgcctaaccagaatgatggtgttgacgctgatggaagccac
agcagttccccaactgttttgaattctagtggcagaatggatgaatctgtttggcgacca
tattga |
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