KEGG   Homo sapiens (human): 8621
Entry
8621              CDS       T01001                                 
Symbol
CDK13, CDC2L, CDC2L5, CHDFIDD, CHED, hCDK13
Name
(RefSeq) cyclin dependent kinase 13
  KO
K08819  cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
Organism
hsa  Homo sapiens (human)
Disease
H02454  Congenital heart defects, dysmorphic facial features, and intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8621 (CDK13)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     8621 (CDK13)
    2.7.11.23  [RNA-polymerase]-subunit kinase
     8621 (CDK13)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  CDK family
   8621 (CDK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Haspin_kinase ABC1 Kinase-like Kdo Pkinase_fungal
Other DBs
NCBI-GeneID: 8621
NCBI-ProteinID: NP_003709
OMIM: 603309
HGNC: 1733
Ensembl: ENSG00000065883
Pharos: Q14004(Tbio)
UniProt: Q14004 Q9BVE2 A0A024RA85
Structure
Position
7:39950256..40099580
AA seq 1512 aa
MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGE
ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPS
PYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHS
RSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAA
EAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTK
PPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHV
ALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDD
LSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVY
KARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDF
KKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKC
SNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
GCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKL
REEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHEL
WSKKRRRQKQMGMTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLPSSQLKSQGSSNVAPVK
TGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGE
KQTDPSTPQQESSKPLGGIQPSSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGG
IDYQAGDTYVSTSDYKDNFGSSSFSSAPYVSNDGLGSSSAPPLERRSFIGNSDIQSLDNY
STASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQGPGYSQGYRGHIST
STGRGRGRGLPY
NT seq 4539 nt   +upstreamnt  +downstreamnt
atgccgagcagctcggacacggcgctggggggaggcgggggcctgagctgggcggagaag
aagttggaggaacgccgcaagcggaggcgattcctgtcccctcagcagccgccgctgctg
ttgccgctcctgcagccgcagctcctgcaaccgccgccgcccccgccgcctctgctcttc
ctggctgctcccggcacggccgccgccgcagccgccgccgccgcggcctcctcctcttgc
ttcagcccgggcccccctctggaggtcaagcggctggcgagaggcaagaggcgcgcagga
gggcggcagaagcggcgtcgcgggccccgcgccgggcaggaggcggagaagcgtcgggtc
ttctcgctgccccagccgcagcaggacggcggtggcggtgctagtagcggcgggggtgtg
accccgctggtggaatacgaggatgtgagctcccagtccgagcaggggctgctgctgggg
ggggccagcgcggcaacggcggcgacggctgccgggggaacggggggcagcggcgggagt
ccggcctcctcctccggcacccagcggcgcggggaggggtcggagcgcaggccccgccgg
gaccgccgcagcagcagtggccgcagcaaggagcgccaccgcgagcaccggcggcgggat
gggcagcgcggtggcagcgaggcctccaagtcccgcagccgccacagccacagcggcgag
gaacgggccgaggtcgccaagagcggcagcagcagcagcagcggcggccgccggaaaagc
gcttcggccacatccagcagcagtagcagccgcaaggaccgggactcgaaggcccaccgc
agccggactaagtcgtccaaggagccgccttcggcctacaaggaaccgcccaaggcctac
cgggaggacaagaccgagcctaaggcctacaggcggcggcggtccctcagcccactggga
ggccgggacgacagcccggtgtcccacagggcctctcagagcctgaggagccgcaagtcc
cccagcccggcaggaggtggcagcagcccctattctcggcggctgccgcgctccccgagc
ccctacagtcgccgccgctcccccagctacagccgccacagctcctacgagcggggcggc
gacgtgtcccctagtccctacagcagcagcagctggcgccgctctcgcagtccctacagc
cctgtgctcagacggtctggaaaatcccgaagcagaagcccgtattcatctaggcattca
agatctcgtagcaggcacagattgtctagatccagaagtcgtcattctagtatttctcct
agcacactaactctgaagagtagcctggcagctgaattgaacaagaataaaaaagcacga
gcagcagaggcagcaagagccgcagaagcagcgaaagctgcagaagcaactaaggctgct
gaggctgctgccaaggctgcaaaagcttcaaacacttctacacctaccaaggggaacacg
gaaactagtgccagtgcatcacaaacaaaccatgtgaaggatgtgaagaaaattaaaatt
gaacatgcaccttctccctcaagtggtggaactttaaaaaatgacaaagcaaaaacaaag
ccacctcttcaggtaacgaaggtggaaaataatttgattgtagataaagccaccaagaaa
gcagtcatagttggaaaggagagtaaatctgctgctacaaaggaggaatcagtatctctt
aaagagaaaaccaaaccacttacaccaagcataggagccaaggagaaggagcaacatgta
gctttagtcacctctacattaccaccgttacctttgcctcccatgctgcctgaagataaa
gaagctgatagcttacgaggaaatatttcagtaaaagcagttaaaaaagaagtagaaaag
aaactccgatgtcttcttgctgatttaccgctgccccctgagctaccaggaggagatgat
ctttcaaagagtccagaggaaaagaaaacagcaacacagttacatagtaaaaggaggcct
aaaatatgtgggcctcgctatggtgaaaccaaagaaaaagatattgactggggaaaacgc
tgcgtggataaatttgatatcatcggaattattggagaaggtacttacggacaagtttac
aaagccagggataaagacactggagaaatggtagccttaaaaaaagtacgtctggataat
gaaaaggaaggctttccaattacagcaattcgagaaattaaaattctccggcagcttacc
catcagagtattatcaatatgaaggaaatagtgactgataaagaagatgctttggatttc
aagaaggacaaaggtgcattttatctggtgtttgaatatatggaccatgatctgatggga
ctactggaatcaggcttggttcattttaatgaaaatcacataaagtcatttatgagacag
ctcatggagggtctggattattgtcataagaagaactttttgcatagagatattaaatgt
tccaatatccttctaaataatagagggcagataaaacttgcagactttggacttgctcga
ttgtatagctcagaagaaagtcggccgtatactaacaaggtaattactttatggtaccgt
ccacctgaactgctactgggagaagaacgatacacaccagccattgatgtatggagctgt
ggctgtatccttggcgaactcttcactaaaaaacctatatttcaagcaaatcaggaactt
gcacaactagaattaataagccgaatatgtgggagtccatgtcctgcagtgtggcctgat
gtaatcaaactaccatatttcaacaccatgaaaccaaagaagcaatatcgtcgaaagtta
agagaagaatttgtttttattcctgcagctgcgctagacttatttgattacatgcttgcc
ttggatcctagtaagcgctgcactgctgaacaggctcttcagtgcgagttcctccgagat
gtggaaccctcaaaaatgcctccaccagatctccctttatggcaagattgtcatgagtta
tggagtaaaaagcgaagaagacagaagcagatgggcatgactgatgatgtttccacaatt
aaagcccccaggaaggacttgtctctgggcttggatgacagcagaaccaacacaccccag
ggtgtgctgccatcttcacagctgaaatctcagggcagctcaaatgtggcacctgtaaaa
acaggccctggacagcacttaaaccacagtgaattggcaattctactaaacctactacaa
tctaaaacaagtgttaatatggctgattttgtccaagtgttgaacattaaggtaaactct
gagactcaacagcagctaaataaaataaaccttcctgctggaattttggcaacaggtgaa
aaacagacagatccatcaacaccacaacaggagtcttcgaaaccgttgggaggaattcag
ccttcttctcagaccatccagcctaaagtggagactgatgctgcccaggcggctgtgcag
agtgcatttgcagttctgttgactcagttaataaaggctcagcagtcaaagcagaaagat
gtgctactagaagagagggaaaatggatcgggacatgaagcgtcattacaactcaggcca
cctccagaacctagcactccggtgtcgggacaagatgacctcatccagcatcaagatatg
aggatcttggagctaacgccagaaccagaccggcctcgaattctgcctcctgaccaacga
cctcccgagcctcctgaaccaccaccagtcactgaggaagatctagattatcggacagaa
aaccagcatgtacccaccaccagttcttcattaactgaccctcatgccggagtgaaggca
gccctgttacagctgcttgctcagcatcagccccaggatgaccccaaaagagaaggtggg
attgattatcaagcaggagacacttacgtgtccacttcagactacaaggacaactttgga
tcctcttctttctcttctgctccttatgttagcaatgatggtctaggaagcagttctgct
ccaccactagaacgacgtagtttcattggaaattcagatattcagtctttggataactac
agtactgcttcatctcattctggtggtccacctcagccttctgccttttctgagtcattt
cccagttcagtagctggatatggagacatttacctcaatgctggtcccatgttgtttagt
ggagacaaggaccatagatttgaatatagccatggtcctattgcagtcctggcaaacagc
agtgacccttccacggggccagagagtactcatcctttgccagcaaagatgcacaactat
aactatggtggtaacttacaggaaaatccgagtggccccagcctcatgcatggacagacc
tggacttctcctgcccaaggacctggatattcacaaggatacaggggacatattagcaca
tcaactggcagaggcagaggcagagggttaccatactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (49)   
   KEGG ORTHOLOGY (1)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (9)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (37)   
   RefSeq(nuc) (5)   
   GenBank (16)   
   EMBL (16)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (113)   

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