KEGG   Homo sapiens (human): 8621
Entry
8621              CDS       T01001                                 
Symbol
CDK13, CDC2L, CDC2L5, CHDFIDD, CHED, hCDK13
Name
(RefSeq) cyclin dependent kinase 13
  KO
K08819  cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
Organism
hsa  Homo sapiens (human)
Disease
H02454  Congenital heart defects, dysmorphic facial features, and intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8621 (CDK13)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     8621 (CDK13)
    2.7.11.23  [RNA-polymerase]-subunit kinase
     8621 (CDK13)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  CDK family
   8621 (CDK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Haspin_kinase ABC1 THRAP3_BCLAF1 Kinase-like Pkinase_fungal Kdo
Other DBs
NCBI-GeneID: 8621
NCBI-ProteinID: NP_003709
OMIM: 603309
HGNC: 1733
Ensembl: ENSG00000065883
UniProt: Q14004 Q9BVE2
Structure
Position
7:39950256..40099580
AA seq 1512 aa
MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGE
ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPS
PYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHS
RSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAA
EAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTK
PPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHV
ALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDD
LSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVY
KARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDF
KKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKC
SNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
GCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKL
REEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHEL
WSKKRRRQKQMGMTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLPSSQLKSQGSSNVAPVK
TGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGE
KQTDPSTPQQESSKPLGGIQPSSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGG
IDYQAGDTYVSTSDYKDNFGSSSFSSAPYVSNDGLGSSSAPPLERRSFIGNSDIQSLDNY
STASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQGPGYSQGYRGHIST
STGRGRGRGLPY
NT seq 4539 nt   +upstreamnt  +downstreamnt
atgccgagcagctcggacacggcgctggggggaggcgggggcctgagctgggcggagaag
aagttggaggaacgccgcaagcggaggcgattcctgtcccctcagcagccgccgctgctg
ttgccgctcctgcagccgcagctcctgcaaccgccgccgcccccgccgcctctgctcttc
ctggctgctcccggcacggccgccgccgcagccgccgccgccgcggcctcctcctcttgc
ttcagcccgggcccccctctggaggtcaagcggctggcgagaggcaagaggcgcgcagga
gggcggcagaagcggcgtcgcgggccccgcgccgggcaggaggcggagaagcgtcgggtc
ttctcgctgccccagccgcagcaggacggcggtggcggtgctagtagcggcgggggtgtg
accccgctggtggaatacgaggatgtgagctcccagtccgagcaggggctgctgctgggg
ggggccagcgcggcaacggcggcgacggctgccgggggaacggggggcagcggcgggagt
ccggcctcctcctccggcacccagcggcgcggggaggggtcggagcgcaggccccgccgg
gaccgccgcagcagcagtggccgcagcaaggagcgccaccgcgagcaccggcggcgggat
gggcagcgcggtggcagcgaggcctccaagtcccgcagccgccacagccacagcggcgag
gaacgggccgaggtcgccaagagcggcagcagcagcagcagcggcggccgccggaaaagc
gcttcggccacatccagcagcagtagcagccgcaaggaccgggactcgaaggcccaccgc
agccggactaagtcgtccaaggagccgccttcggcctacaaggaaccgcccaaggcctac
cgggaggacaagaccgagcctaaggcctacaggcggcggcggtccctcagcccactggga
ggccgggacgacagcccggtgtcccacagggcctctcagagcctgaggagccgcaagtcc
cccagcccggcaggaggtggcagcagcccctattctcggcggctgccgcgctccccgagc
ccctacagtcgccgccgctcccccagctacagccgccacagctcctacgagcggggcggc
gacgtgtcccctagtccctacagcagcagcagctggcgccgctctcgcagtccctacagc
cctgtgctcagacggtctggaaaatcccgaagcagaagcccgtattcatctaggcattca
agatctcgtagcaggcacagattgtctagatccagaagtcgtcattctagtatttctcct
agcacactaactctgaagagtagcctggcagctgaattgaacaagaataaaaaagcacga
gcagcagaggcagcaagagccgcagaagcagcgaaagctgcagaagcaactaaggctgct
gaggctgctgccaaggctgcaaaagcttcaaacacttctacacctaccaaggggaacacg
gaaactagtgccagtgcatcacaaacaaaccatgtgaaggatgtgaagaaaattaaaatt
gaacatgcaccttctccctcaagtggtggaactttaaaaaatgacaaagcaaaaacaaag
ccacctcttcaggtaacgaaggtggaaaataatttgattgtagataaagccaccaagaaa
gcagtcatagttggaaaggagagtaaatctgctgctacaaaggaggaatcagtatctctt
aaagagaaaaccaaaccacttacaccaagcataggagccaaggagaaggagcaacatgta
gctttagtcacctctacattaccaccgttacctttgcctcccatgctgcctgaagataaa
gaagctgatagcttacgaggaaatatttcagtaaaagcagttaaaaaagaagtagaaaag
aaactccgatgtcttcttgctgatttaccgctgccccctgagctaccaggaggagatgat
ctttcaaagagtccagaggaaaagaaaacagcaacacagttacatagtaaaaggaggcct
aaaatatgtgggcctcgctatggtgaaaccaaagaaaaagatattgactggggaaaacgc
tgcgtggataaatttgatatcatcggaattattggagaaggtacttacggacaagtttac
aaagccagggataaagacactggagaaatggtagccttaaaaaaagtacgtctggataat
gaaaaggaaggctttccaattacagcaattcgagaaattaaaattctccggcagcttacc
catcagagtattatcaatatgaaggaaatagtgactgataaagaagatgctttggatttc
aagaaggacaaaggtgcattttatctggtgtttgaatatatggaccatgatctgatggga
ctactggaatcaggcttggttcattttaatgaaaatcacataaagtcatttatgagacag
ctcatggagggtctggattattgtcataagaagaactttttgcatagagatattaaatgt
tccaatatccttctaaataatagagggcagataaaacttgcagactttggacttgctcga
ttgtatagctcagaagaaagtcggccgtatactaacaaggtaattactttatggtaccgt
ccacctgaactgctactgggagaagaacgatacacaccagccattgatgtatggagctgt
ggctgtatccttggcgaactcttcactaaaaaacctatatttcaagcaaatcaggaactt
gcacaactagaattaataagccgaatatgtgggagtccatgtcctgcagtgtggcctgat
gtaatcaaactaccatatttcaacaccatgaaaccaaagaagcaatatcgtcgaaagtta
agagaagaatttgtttttattcctgcagctgcgctagacttatttgattacatgcttgcc
ttggatcctagtaagcgctgcactgctgaacaggctcttcagtgcgagttcctccgagat
gtggaaccctcaaaaatgcctccaccagatctccctttatggcaagattgtcatgagtta
tggagtaaaaagcgaagaagacagaagcagatgggcatgactgatgatgtttccacaatt
aaagcccccaggaaggacttgtctctgggcttggatgacagcagaaccaacacaccccag
ggtgtgctgccatcttcacagctgaaatctcagggcagctcaaatgtggcacctgtaaaa
acaggccctggacagcacttaaaccacagtgaattggcaattctactaaacctactacaa
tctaaaacaagtgttaatatggctgattttgtccaagtgttgaacattaaggtaaactct
gagactcaacagcagctaaataaaataaaccttcctgctggaattttggcaacaggtgaa
aaacagacagatccatcaacaccacaacaggagtcttcgaaaccgttgggaggaattcag
ccttcttctcagaccatccagcctaaagtggagactgatgctgcccaggcggctgtgcag
agtgcatttgcagttctgttgactcagttaataaaggctcagcagtcaaagcagaaagat
gtgctactagaagagagggaaaatggatcgggacatgaagcgtcattacaactcaggcca
cctccagaacctagcactccggtgtcgggacaagatgacctcatccagcatcaagatatg
aggatcttggagctaacgccagaaccagaccggcctcgaattctgcctcctgaccaacga
cctcccgagcctcctgaaccaccaccagtcactgaggaagatctagattatcggacagaa
aaccagcatgtacccaccaccagttcttcattaactgaccctcatgccggagtgaaggca
gccctgttacagctgcttgctcagcatcagccccaggatgaccccaaaagagaaggtggg
attgattatcaagcaggagacacttacgtgtccacttcagactacaaggacaactttgga
tcctcttctttctcttctgctccttatgttagcaatgatggtctaggaagcagttctgct
ccaccactagaacgacgtagtttcattggaaattcagatattcagtctttggataactac
agtactgcttcatctcattctggtggtccacctcagccttctgccttttctgagtcattt
cccagttcagtagctggatatggagacatttacctcaatgctggtcccatgttgtttagt
ggagacaaggaccatagatttgaatatagccatggtcctattgcagtcctggcaaacagc
agtgacccttccacggggccagagagtactcatcctttgccagcaaagatgcacaactat
aactatggtggtaacttacaggaaaatccgagtggccccagcctcatgcatggacagacc
tggacttctcctgcccaaggacctggatattcacaaggatacaggggacatattagcaca
tcaactggcagaggcagaggcagagggttaccatactga

  All links  
Disease (2)   
   OMIM (2)   
Gene (47)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (11)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (40)   
   RefSeq(nuc) (8)   
   GenBank (16)   
   EMBL (16)   
3D Structure (2)   
   PDB (2)   
Protein domain (8)   
   Pfam (8)   
All databases (110)   

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