KEGG   Homo sapiens (human): 8635
Entry
8635              CDS       T01001                                 

Gene name
RNASET2, RNASE6PL, bA514O12.3
Definition
(RefSeq) ribonuclease T2
  KO
K01166  ribonuclease T2 [EC:4.6.1.19]
Organism
hsa  Homo sapiens (human)
Disease
H00878  Cystic leukoencephalopathy without megalencephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:hsa03016]
    8635 (RNASET2)
Enzymes [BR:hsa01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.19  ribonuclease T2
     8635 (RNASET2)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  3'processing and CCA adding factors
   3'processing factors
    8635 (RNASET2)
 Prokaryotic type
    8635 (RNASET2)
SSDB
Motif
Pfam: Ribonuclease_T2 DHODB_Fe-S_bind
Other DBs
NCBI-GeneID: 8635
NCBI-ProteinID: NP_003721
OMIM: 612944
HGNC: 21686
Ensembl: ENSG00000026297
Vega: OTTHUMG00000016009
Pharos: O00584(Tbio)
UniProt: O00584
Structure
PDB: 
3T0O

Position
6q27
AA seq 256 aa
MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPD
YWTIHGLWPDKSEGCNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGT
CAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIP
KIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRV
CEDGPVFYPPPKKTKH
NT seq 771 nt   +upstreamnt  +downstreamnt
atgcgccctgcagccctgcgcggggccctgctgggctgcctctgcctggcgttgctttgc
ctgggcggtgcggacaagcgcctgcgtgacaaccatgagtggaaaaaactaattatggtt
cagcactggcctgagacagtatgcgagaaaattcaaaacgactgtagagaccctccggat
tactggacaatacatggactatggcccgataaaagtgaaggatgtaatagatcgtggccc
ttcaatttagaagagattaaggatcttttgccagaaatgagggcatactggcctgacgta
attcactcgtttcccaatcgcagccgcttctggaagcatgagtgggaaaagcatgggacc
tgcgccgcccaggtggatgcgctcaactcccagaagaagtactttggcagaagcctggaa
ctctacagggagctggacctcaacagtgtgcttctaaaattggggataaaaccatccatc
aattactaccaagttgcagattttaaagatgcccttgccagagtatatggagtgataccc
aaaatccagtgccttccaccaagccaggatgaggaagtacagacaattggtcagatagaa
ctgtgcctcactaagcaagaccagcagctgcaaaactgcaccgagccgggggagcagccg
tcccccaagcaggaagtctggctggcaaatggggccgccgagagccggggtctgagagtc
tgtgaagatggcccagtcttctatcccccacctaaaaagaccaagcattga

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