KEGG   Homo sapiens (human): 8714
Entry
8714              CDS       T01001                                 
Symbol
ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2
Name
(RefSeq) ATP binding cassette subfamily C member 3
  KO
K05667  ATP-binding cassette, subfamily C (CFTR/MRP), member 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa01523  Antifolate resistance
hsa02010  ABC transporters
hsa04976  Bile secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    8714 (ABCC3)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    8714 (ABCC3)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    8714 (ABCC3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    8714 (ABCC3)
Transporters [BR:hsa02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
    8714 (ABCC3)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N MMR_HSR1 AAA_16 RsgA_GTPase ABC_ATPase AAA_25 RNA_helicase AAA Dynamin_N dNK AAA_PrkA
Other DBs
NCBI-GeneID: 8714
NCBI-ProteinID: NP_003777
OMIM: 604323
HGNC: 54
Ensembl: ENSG00000108846
Pharos: O15438(Tbio)
UniProt: O15438
Position
17:50634881..50692253
AA seq 1527 aa
MDALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHC
RGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLAT
LLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFAL
VLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDL
WSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFL
KALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCS
MMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRF
MDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQ
MKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWM
CSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLK
RIQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVV
GPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRY
QQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSA
VDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQ
RNGSFANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTYVVQ
KQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFW
DYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTSLRLGVYAALGI
LQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVD
EVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLE
SVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVE
FVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERV
KEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVG
IVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTL
RMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARAL
LRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGV
VAEFDSPANLIAARGIFYGMARDAGLA
NT seq 4584 nt   +upstreamnt  +downstreamnt
atggacgccctgtgcggttccggggagctcggctccaagttctgggactccaacctgtct
gtgcacacagaaaacccggacctcactccctgcttccagaactccctgctggcctgggtg
ccctgcatctacctgtgggtcgccctgccctgctacttgctctacctgcggcaccattgt
cgtggctacatcatcctctcccacctgtccaagctcaagatggtcctgggtgtcctgctg
tggtgcgtctcctgggcggaccttttttactccttccatggcctggtccatggccgggcc
cctgcccctgttttctttgtcacccccttggtggtgggggtcaccatgctgctggccacc
ctgctgatacagtatgagcggctgcagggcgtacagtcttcgggggtcctcattatcttc
tggttcctgtgtgtggtctgcgccatcgtcccattccgctccaagatccttttagccaag
gcagagggtgagatctcagaccccttccgcttcaccaccttctacatccactttgccctg
gtactctctgccctcatcttggcctgcttcagggagaaacctccatttttctccgcaaag
aatgtcgaccctaacccctaccctgagaccagcgctggctttctctcccgcctgtttttc
tggtggttcacaaagatggccatctatggctaccggcatcccctggaggagaaggacctc
tggtccctaaaggaagaggacagatcccagatggtggtgcagcagctgctggaggcatgg
aggaagcaggaaaagcagacggcacgacacaaggcttcagcagcacctgggaaaaatgcc
tccggcgaggacgaggtgctgctgggtgcccggcccaggccccggaagccctccttcctg
aaggccctgctggccaccttcggctccagcttcctcatcagtgcctgcttcaagcttatc
caggacctgctctccttcatcaatccacagctgctcagcatcctgatcaggtttatctcc
aaccccatggccccctcctggtggggcttcctggtggctgggctgatgttcctgtgctcc
atgatgcagtcgctgatcttacaacactattaccactacatctttgtgactggggtgaag
tttcgtactgggatcatgggtgtcatctacaggaaggctctggttatcaccaactcagtc
aaacgtgcgtccactgtgggggaaattgtcaacctcatgtcagtggatgcccagcgcttc
atggaccttgcccccttcctcaatctgctgtggtcagcacccctgcagatcatcctggcg
atctacttcctctggcagaacctaggtccctctgtcctggctggagtcgctttcatggtc
ttgctgattccactcaacggagctgtggccgtgaagatgcgcgccttccaggtaaagcaa
atgaaattgaaggactcgcgcatcaagctgatgagtgagatcctgaacggcatcaaggtg
ctgaagctgtacgcctgggagcccagcttcctgaagcaggtggagggcatcaggcagggt
gagctccagctgctgcgcacggcggcctacctccacaccacaaccaccttcacctggatg
tgcagccccttcctggtgaccctgatcaccctctgggtgtacgtgtacgtggacccaaac
aatgtgctggacgccgagaaggcctttgtgtctgtgtccttgtttaatatcttaagactt
cccctcaacatgctgccccagttaatcagcaacctgactcaggccagtgtgtctctgaaa
cggatccagcaattcctgagccaagaggaacttgacccccagagtgtggaaagaaagacc
atctccccaggctatgccatcaccatacacagtggcaccttcacctgggcccaggacctg
ccccccactctgcacagcctagacatccaggtcccgaaaggggcactggtggccgtggtg
gggcctgtgggctgtgggaagtcctccctggtgtctgccctgctgggagagatggagaag
ctagaaggcaaagtgcacatgaagggctccgtggcctatgtgccccagcaggcatggatc
cagaactgcactcttcaggaaaacgtgcttttcggcaaagccctgaaccccaagcgctac
cagcagactctggaggcctgtgccttgctagctgacctggagatgctgcctggtggggat
cagacagagattggagagaagggcattaacctgtctgggggccagcggcagcgggtcagt
ctggctcgagctgtttacagtgatgccgatattttcttgctggatgacccactgtccgcg
gtggactctcatgtggccaagcacatctttgaccacgtcatcgggccagaaggcgtgctg
gcaggcaagacgcgagtgctggtgacgcacggcattagcttcctgccccagacagacttc
atcattgtgctagctgatggacaggtgtctgagatgggcccgtacccagccctgctgcag
cgcaacggctcctttgccaactttctctgcaactatgcccccgatgaggaccaagggcac
ctggaggacagctggaccgcgttggaaggtgcagaggataaggaggcactgctgattgaa
gacacactcagcaaccacacggatctgacagacaatgatccagtcacctatgtggtccag
aagcagtttatgagacagctgagtgccctgtcctcagatggggagggacagggtcggcct
gtaccccggaggcacctgggtccatcagagaaggtgcaggtgacagaggcgaaggcagat
ggggcactgacccaggaggagaaagcagccattggcactgtggagctcagtgtgttctgg
gattatgccaaggccgtggggctctgtaccacgctggccatctgtctcctgtatgtgggt
caaagtgcggctgccattggagccaatgtgtggctcagtgcctggacaaatgatgccatg
gcagacagtagacagaacaacacttccctgaggctgggcgtctatgctgctttaggaatt
ctgcaagggttcttggtgatgctggcagccatggccatggcagcgggtggcatccaggct
gcccgtgtgttgcaccaggcactgctgcacaacaagatacgctcgccacagtccttcttt
gacaccacaccatcaggccgcatcctgaactgcttctccaaggacatctatgtcgttgat
gaggttctggcccctgtcatcctcatgctgctcaattccttcttcaacgccatctccact
cttgtggtcatcatggccagcacgccgctcttcactgtggtcatcctgcccctggctgtg
ctctacaccttagtgcagcgcttctatgcagccacatcacggcaactgaagcggctggaa
tcagtcagccgctcacctatctactcccacttttcggagacagtgactggtgccagtgtc
atccgggcctacaaccgcagccgggattttgagatcatcagtgatactaaggtggatgcc
aaccagagaagctgctacccctacatcatctccaaccggtggctgagcatcggagtggag
ttcgtggggaactgcgtggtgctctttgctgcactatttgccgtcatcgggaggagcagc
ctgaacccggggctggtgggcctttctgtgtcctactccttgcaggtgacatttgctctg
aactggatgatacgaatgatgtcagatttggaatctaacatcgtggctgtggagagggtc
aaggagtactccaagacagagacagaggcgccctgggtggtggaaggcagccgccctccc
gaaggttggcccccacgtggggaggtggagttccggaattattctgtgcgctaccggccg
ggcctagacctggtgctgagagacctgagtctgcatgtgcacggtggcgagaaggtgggg
atcgtgggccgcactggggctggcaagtcttccatgaccctttgcctgttccgcatcctg
gaggcggcaaagggtgaaatccgcattgatggcctcaatgtggcagacatcggcctccat
gacctgcgctctcagctgaccatcatcccgcaggaccccatcctgttctcggggaccctg
cgcatgaacctggaccccttcggcagctactcagaggaggacatttggtgggctttggag
ctgtcccacctgcacacgtttgtgagctcccagccggcaggcctggacttccagtgctca
gagggcggggagaatctcagcgtgggccagaggcagctcgtgtgcctggcccgagccctg
ctccgcaagagccgcatcctggttttagacgaggccacagctgccatcgacctggagact
gacaacctcatccaggctaccatccgcacccagtttgatacctgcactgtcctgaccatc
gcacaccggcttaacactatcatggactacaccagggtcctggtcctggacaaaggagta
gtagctgaatttgattctccagccaacctcattgcagctagaggcatcttctacgggatg
gccagagatgctggacttgcctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (52)   
   KEGG ORTHOLOGY (1)   
   RefGene (41)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (48)   
   RefSeq(nuc) (4)   
   GenBank (22)   
   EMBL (22)   
Protein domain (13)   
   Pfam (13)   
All databases (124)   

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