| Entry |
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| Symbol |
MBTPS1, CAOP, PCSK8, S1P, SEDKF, SKI-1
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| Name |
(RefSeq) membrane bound transcription factor peptidase, site 1
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| KO |
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| Organism |
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| Pathway |
| hsa04141 | Protein processing in endoplasmic reticulum |
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| Disease |
| H02462 | Spondyloepiphyseal dysplasia |
| H02955 | Cataract, alopecia, oral mucosal disorder, and psoriasis-like syndrome |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
8720 (MBTPS1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:hsa01002]
8720 (MBTPS1)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:hsa03110]
8720 (MBTPS1)
Enzymes [BR:hsa01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.112 site-1 protease
8720 (MBTPS1)
Peptidases and inhibitors [BR:hsa01002]
Serine peptidases
Family S8: subtilisin family
8720 (MBTPS1)
Chaperones and folding catalysts [BR:hsa03110]
Intramolecular chaperones
Subtilisin family
8720 (MBTPS1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
16:complement(84053763..84116942)
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| AA seq |
1052 aa
MKLVNIWLLLLVVLLCGKKHLGDRLEKKSFEKAPCPGCSHLTLKVEFSSTVVEYEYIVAF
NGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDH
PNIKRVTPQRKVFRSLKYAESDPTVPCNETRWSQKWQSSRPLRRASLSLGSGFWHATGRH
SSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNE
RTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKK
IDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGG
IDFEDNIARFSSRGMTTWELPGGYGRMKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVV
AGAVTLLVSTVQKRELVNPASMKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYKP
QASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQ
NGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAE
QTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTN
FRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSL
VIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTL
ANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGR
IVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERM
EGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKV
VLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQ
INKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV |
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| NT seq |
3159 nt +upstreamnt +downstreamnt
atgaagcttgtcaacatctggctgcttctgctcgtggttttgctctgtgggaagaaacat
ctgggcgacagactggaaaagaaatcttttgaaaaggccccatgccctggctgttcccac
ctgactttgaaggtggaattctcatcaacagttgtggaatatgaatatattgtggctttc
aatggatactttacagccaaagctagaaattcatttatttcaagtgccctgaagagcagt
gaagtagacaattggagaattatacctcgaaacaatccatccagtgactaccctagtgat
tttgaggtgattcagataaaagaaaaacagaaagcggggctgctaacacttgaagatcat
ccaaacatcaaacgggtcacgccccaacgaaaagtctttcgttccctcaagtatgctgaa
tctgaccccacagtaccctgcaatgaaacccggtggagccagaagtggcaatcatcacgt
cccctgcgaagagccagcctctccctgggctctggcttctggcatgctacgggaaggcat
tcgagcagacggctgctgagagccatcccgcgccaggttgcccagacactgcaggcagat
gtgctctggcagatgggatatacaggtgctaatgtaagagttgctgtttttgacactggg
ctgagcgagaagcatccccacttcaaaaatgtgaaggagagaaccaactggaccaacgag
cgaacgctggacgatgggttgggccatggcacattcgtggcaggtgtgatagccagcatg
agggagtgccaaggatttgctccagatgcagaacttcacattttcagggtctttaccaat
aatcaggtatcttacacatcttggtttttggacgccttcaactatgccattttaaagaag
atcgacgtgttaaacctcagcatcggcggcccggacttcatggatcatccgtttgttgac
aaggtgtgggaattaacagctaacaatgtaatcatggtttctgctattggcaatgacgga
cctctttatggcactctgaataaccctgctgatcaaatggatgtgattggagtaggcggc
attgactttgaagataacatcgcccgcttttcttcaaggggaatgactacctgggagcta
ccaggaggctacggtcgcatgaaacctgacattgtcacctatggtgctggcgtgcggggt
tctggcgtgaaaggggggtgccgggccctctcagggaccagtgttgcttctccagtggtt
gcaggtgctgtcaccttgttagtgagcacagtccagaagcgtgagctggtgaatcccgcc
agtatgaagcaggccctgatcgcgtcagcccggaggctccccggggtcaacatgtttgag
caaggccacggcaagctcgatctgctcagagcctatcagatcctcaacagctacaagcca
caggcaagtttgagccccagctacatagatctgactgagtgtccctacatgtggccctac
tgctcccagcccatctactatggaggaatgccgacagttgttaatgtcaccatcctcaac
ggcatgggagtcacaggaagaattgtagataagcctgactggcagccctatttgccacag
aacggagacaacattgaagttgccttctcctactcctcggtcttatggccttggtcgggc
tacctggccatctccatttctgtgaccaagaaagcggcttcctgggaaggcattgctcag
ggccatgtcatgatcactgtggcttccccagcagagacagagtcaaaaaatggtgcagaa
cagacttcaacagtaaagctccccattaaggtgaagataattcctactcccccgcgaagc
aagagagttctctgggatcagtaccacaacctccgctatccacctggctatttccccagg
gataatttaaggatgaagaatgaccctttagactggaatggtgatcacatccacaccaat
ttcagggatatgtaccagcatctgagaagcatgggctactttgtagaggtcctcggggcc
cccttcacgtgttttgatgccagtcagtatggcactttgctgatggtggacagtgaggag
gagtacttccctgaagagatcgccaagctccggagggacgtggacaacggcctctcgctc
gtcatcttcagtgactggtacaacacttctgttatgagaaaagtgaagttttatgatgaa
aacacaaggcagtggtggatgccggataccggaggagctaacatcccagctctgaatgag
ctgctgtctgtgtggaacatggggttcagcgatggcctgtatgaaggggagttcaccctg
gccaaccatgacatgtattatgcgtcagggtgcagcatcgcgaagtttccagaagatggc
gtcgtgataacacagactttcaaggaccaaggattggaggttttaaagcaggaaacagca
gttgttgaaaacgtccccattttgggactttatcagattccagctgagggtggaggccgg
attgtactgtatggggactccaattgcttggatgacagtcaccgacagaaggactgcttt
tggcttctggatgccctcctccagtacacatcgtatggggtgacaccgcctagcctcagt
cactctgggaaccgccagcgccctcccagtggagcaggctcagtcactccagagaggatg
gaaggaaaccatcttcatcggtactccaaggttctggaggcccatttgggagacccaaaa
cctcggcctctaccagcctgtccacgcttgtcttgggccaagccacagcctttaaacgag
acggcgcccagtaacctttggaaacatcagaagctactctccattgacctggacaaggtg
gtgttacccaactttcgatcgaatcgccctcaagtgaggcccttgtcccctggagagagc
ggcgcctgggacattcctggagggatcatgcctggccgctacaaccaggaggtgggccag
accattcctgtctttgccttcctgggagccatggtggtcctggccttctttgtggtacaa
atcaacaaggccaagagcaggccgaagcggaggaagcccagggtgaagcgcccgcagctc
atgcagcaggttcacccgccaaagaccccttcggtgtga |
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