KEGG   Homo sapiens (human): 8741
Entry
8741              CDS       T01001                                 
Symbol
TNFSF13, APRIL, CD256, TALL-2, TALL2, TNLG7B, TRDL-1, UNQ383/PRO715, ZTNF2
Name
(RefSeq) TNF superfamily member 13
  KO
K05475  tumor necrosis factor ligand superfamily member 13
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04672  Intestinal immune network for IgA production
hsa05323  Rheumatoid arthritis
Network
nt06516  TNF signaling
  Element
N01801  TNFSF13-TNFRSF13B/C signaling pathway
Drug target
Atacicept: D09704
Sibeprenlimab: D12374
Zigakibart: D12800
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    8741 (TNFSF13)
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    8741 (TNFSF13)
 09160 Human Diseases
  09163 Immune disease
   05323 Rheumatoid arthritis
    8741 (TNFSF13)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    8741 (TNFSF13)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    8741 (TNFSF13)
   04090 CD molecules [BR:hsa04090]
    8741 (TNFSF13)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     8741 (TNFSF13)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Tumor necrosis fators
   8741 (TNFSF13)
CD molecules [BR:hsa04090]
 Proteins
  8741 (TNFSF13)
SSDB
Motif
Pfam: TNF LapA_dom
Other DBs
NCBI-GeneID: 8741
NCBI-ProteinID: NP_003799
OMIM: 604472
HGNC: 11928
Ensembl: ENSG00000161955
UniProt: O75888
Structure
Position
17:7558282..7561601
AA seq 250 aa
MPASSPFLLAPKGPPGNMGGPVREPALSVALWLSWGAALGAVACAMALLTQQTELQSLRR
EVSRLQGTGGPSQNGEGYPWQSLPEQSSDALEAWENGERSRKRRAVLTQKQKKQHSVLHL
VPINATSKDDSDVTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQ
VVSREGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSP
HGTFLGFVKL
NT seq 753 nt   +upstreamnt  +downstreamnt
atgccagcctcatctcctttcttgctagcccccaaagggcctccaggcaacatggggggc
ccagtcagagagccggcactctcagttgccctctggttgagttggggggcagctctgggg
gccgtggcttgtgccatggctctgctgacccaacaaacagagctgcagagcctcaggaga
gaggtgagccggctgcaggggacaggaggcccctcccagaatggggaagggtatccctgg
cagagtctcccggagcagagttccgatgccctggaagcctgggagaatggggagagatcc
cggaaaaggagagcagtgctcacccaaaaacagaagaagcagcactctgtcctgcacctg
gttcccattaacgccacctccaaggatgactccgatgtgacagaggtgatgtggcaacca
gctcttaggcgtgggagaggcctacaggcccaaggatatggtgtccgaatccaggatgct
ggagtttatctgctgtatagccaggtcctgtttcaagacgtgactttcaccatgggtcag
gtggtgtctcgagaaggccaaggaaggcaggagactctattccgatgtataagaagtatg
ccctcccacccggaccgggcctacaacagctgctatagcgcaggtgtcttccatttacac
caaggggatattctgagtgtcataattccccgggcaagggcgaaacttaacctctctcca
catggaaccttcctggggtttgtgaaactgtga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (57)   
   RefSeq(nuc) (7)   
   GenBank (25)   
   EMBL (25)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (95)   

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