KEGG T01001: 8767

Homo sapiens (human): 8767

Entry

8767 CDS T01001

Gene name

RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP2

Definition

(RefSeq) receptor interacting serine/threonine kinase 2

K08846

receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa04621

NOD-like receptor signaling pathway

hsa04722

Neurotrophin signaling pathway

hsa05131

Shigellosis

hsa05152

Tuberculosis

Brite

KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    8767 (RIPK2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    8767 (RIPK2)
09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    8767 (RIPK2)
   05152 Tuberculosis
    8767 (RIPK2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8767 (RIPK2)
Enzymes [BR:hsa01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8767 (RIPK2)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: TKL group
  RIPK family [OT]
   8767 (RIPK2)

SSDB

Motif

Pfam:

Pkinase_Tyr Pkinase CARD Kdo

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

O43353(Tchem)

UniProt:

O43353 A0A0S2Z4Z8

Structure

PDB:

5NG0 6ES0 5AR2 6HMX 5J7B 5NG3 6RNA 5AR5 6RN8 5J79 5AR4 5AR7 4C8B 5AR8 5NG2 5W5J 5W5O 5AR3 6FU5 6GGS 5YRN 2N83 2N7Z

Position

8q21.3

AA seq 540 aa
MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSER
KDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPL
RFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRS
SKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMY
SVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEI
TFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPET
SRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIIN
PLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTK
PTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM

NT seq 1623 nt +upstreamnt +downstreamnt
atgaacggggaggccatctgcagcgccctgcccaccattccctaccacaaactcgccgac
ctgcgctacctgagccgcggcgcctctggcactgtgtcgtccgcccgccacgcagactgg
cgcgtccaggtggccgtgaagcacctgcacatccacactccgctgctcgacagtgaaaga
aaggatgtcttaagagaagctgaaattttacacaaagctagatttagttacattcttcca
attttgggaatttgcaatgagcctgaatttttgggaatagttactgaatacatgccaaat
ggatcattaaatgaactcctacataggaaaactgaatatcctgatgttgcttggccattg
agatttcgcatcctgcatgaaattgcccttggtgtaaattacctgcacaatatgactcct
cctttacttcatcatgacttgaagactcagaatatcttattggacaatgaatttcatgtt
aagattgcagattttggtttatcaaagtggcgcatgatgtccctctcacagtcacgaagt
agcaaatctgcaccagaaggagggacaattatctatatgccacctgaaaactatgaacct
ggacaaaaatcaagggccagtatcaagcacgatatatatagctatgcagttatcacatgg
gaagtgttatccagaaaacagccttttgaagatgtcaccaatcctttgcagataatgtat
agtgtgtcacaaggacatcgacctgttattaatgaagaaagtttgccatatgatatacct
caccgagcacgtatgatctctctaatagaaagtggatgggcacaaaatccagatgaaaga
ccatctttcttaaaatgtttaatagaacttgaaccagttttgagaacatttgaagagata
acttttcttgaagctgttattcagctaaagaaaacaaagttacagagtgtttcaagtgcc
attcacctatgtgacaagaagaaaatggaattatctctgaacatacctgtaaatcatggt
ccacaagaggaatcatgtggatcctctcagctccatgaaaatagtggttctcctgaaact
tcaaggtccctgccagctcctcaagacaatgattttttatctagaaaagctcaagactgt
tattttatgaagctgcatcactgtcctggaaatcacagttgggatagcaccatttctgga
tctcaaagggctgcattctgtgatcacaagaccactccatgctcttcagcaataataaat
ccactctcaactgcaggaaactcagaacgtctgcagcctggtatagcccagcagtggatc
cagagcaaaagggaagacattgtgaaccaaatgacagaagcctgccttaaccagtcgcta
gatgcccttctgtccagggacttgatcatgaaagaggactatgaacttgttagtaccaag
cctacaaggacctcaaaagtcagacaattactagacactactgacatccaaggagaagaa
tttgccaaagttatagtacaaaaattgaaagataacaaacaaatgggtcttcagccttac
ccggaaatacttgtggtttctagatcaccatctttaaatttacttcaaaataaaagcatg
taa

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