KEGG   Homo sapiens (human): 8772
Entry
8772              CDS       T01001                                 

Gene name
FADD, GIG3, MORT1
Definition
(RefSeq) Fas associated via death domain
  KO
K02373  FAS-associated death domain protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa01524  Platinum drug resistance
hsa04210  Apoptosis
hsa04215  Apoptosis - multiple species
hsa04217  Necroptosis
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04668  TNF signaling pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
hsa05142  Chagas disease
hsa05152  Tuberculosis
hsa05160  Hepatitis C
hsa05161  Hepatitis B
hsa05162  Measles
hsa05163  Human cytomegalovirus infection
hsa05164  Influenza A
hsa05165  Human papillomavirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05200  Pathways in cancer
Network
nt06131  Apoptosis (viruses and bacteria)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06162  Hepatitis B virus (HBV)
nt06163  Hepatitis C virus (HCV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06167  Human cytomegalovirus (HCMV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06231  Apoptosis
nt06263  Hepatocellular carcinoma
nt06414  Apoptosis
nt06460  Alzheimer disease
nt06461  Huntington disease
  Element
N00145  Extrinsic apoptotic pathway
N00146  Crosstalk between extrinsic and intrinsic apoptotic pathways
N00351  HPV E6 to extrinsic apoptotic pathway
N00527  HCV Core to crosstalk between extrinsic and intrinsic apoptotic pathways
N00936  Escherichia NleB1 to crosstalk between extrinsic and intrinsic apoptotic pathways
N01005  Mutation-caused aberrant Abeta to crosstalk between extrinsic and intrinsic apoptotic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    8772 (FADD)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    8772 (FADD)
   04215 Apoptosis - multiple species
    8772 (FADD)
   04217 Necroptosis
    8772 (FADD)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    8772 (FADD)
   04621 NOD-like receptor signaling pathway
    8772 (FADD)
   04622 RIG-I-like receptor signaling pathway
    8772 (FADD)
   04657 IL-17 signaling pathway
    8772 (FADD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8772 (FADD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    8772 (FADD)
   05022 Pathways of neurodegeneration - multiple diseases
    8772 (FADD)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    8772 (FADD)
   05132 Salmonella infection
    8772 (FADD)
   05152 Tuberculosis
    8772 (FADD)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    8772 (FADD)
   05162 Measles
    8772 (FADD)
   05164 Influenza A
    8772 (FADD)
   05161 Hepatitis B
    8772 (FADD)
   05160 Hepatitis C
    8772 (FADD)
   05168 Herpes simplex virus 1 infection
    8772 (FADD)
   05163 Human cytomegalovirus infection
    8772 (FADD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    8772 (FADD)
   05169 Epstein-Barr virus infection
    8772 (FADD)
   05165 Human papillomavirus infection
    8772 (FADD)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    8772 (FADD)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    8772 (FADD)
SSDB
Motif
Pfam: DED Death
Other DBs
NCBI-GeneID: 8772
NCBI-ProteinID: NP_003815
OMIM: 602457
HGNC: 3573
Ensembl: ENSG00000168040
Vega: OTTHUMG00000167264
Pharos: Q13158(Tbio)
UniProt: Q13158
Structure
PDB: 

Position
11q13.3
AA seq 208 aa
MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHT
ELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLK
VSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEV
QQARDLQNRSGAMSPMSWNSDASTSEAS
NT seq 627 nt   +upstreamnt  +downstreamnt
atggacccgttcctggtgctgctgcactcggtgtcgtccagcctgtcgagcagcgagctg
accgagctcaagttcctatgcctcgggcgcgtgggcaagcgcaagctggagcgcgtgcag
agcggcctagacctcttctccatgctgctggagcagaacgacctggagcccgggcacacc
gagctcctgcgcgagctgctcgcctccctgcggcgccacgacctgctgcggcgcgtcgac
gacttcgaggcgggggcggcggccggggccgcgcctggggaagaagacctgtgtgcagca
tttaacgtcatatgtgataatgtggggaaagattggagaaggctggctcgtcagctcaaa
gtctcagacaccaagatcgacagcatcgaggacagatacccccgcaacctgacagagcgt
gtgcgggagtcactgagaatctggaagaacacagagaaggagaacgcaacagtggcccac
ctggtgggggctctcaggtcctgccagatgaacctggtggctgacctggtacaagaggtt
cagcaggcccgtgacctccagaacaggagtggggccatgtccccgatgtcatggaactca
gacgcatctacctccgaagcgtcctga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (26)   
   KEGG PATHWAY (26)   
Network (6)   
   KEGG NETWORK (6)   
Disease (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
Protein domain (2)   
   Pfam (2)   
All databases (87)   

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