KEGG   Homo sapiens (human): 8803Help
Entry
8803              CDS       T01001                                 

Gene name
SUCLA2, A-BETA, A-SCS, MTDPS5, SCS-betaA
Definition
(RefSeq) succinate-CoA ligase ADP-forming beta subunit
  KO
K01900  succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00020  Citrate cycle (TCA cycle)
hsa00640  Propanoate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
Module
hsa_M00009  Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Disease
H00469  Mitochondrial DNA depletion syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    8803 (SUCLA2)
   00640 Propanoate metabolism
    8803 (SUCLA2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    8803 (SUCLA2)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.4  succinate---CoA ligase (GDP-forming)
     8803 (SUCLA2)
    6.2.1.5  succinate---CoA ligase (ADP-forming)
     8803 (SUCLA2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   8803 (SUCLA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ATP-grasp_2 Ligase_CoA ATP-grasp_5 CPSase_L_D2 GARS_A
Motif
Other DBs
NCBI-GeneID: 8803
NCBI-ProteinID: NP_003841
OMIM: 603921
HGNC: 11448
Ensembl: ENSG00000136143
Vega: OTTHUMG00000016889
Pharos: Q9P2R7(Tbio)
UniProt: Q9P2R7 E5KS60 Q9Y4T0
Structure
PDB: 

Position
13q14.2
AA seq 463 aa AA seqDB search
MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA
FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI
ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
NT seq 1392 nt NT seq  +upstreamnt  +downstreamnt
atggcggcctccatgttctacggcaggctagtggccgtggccacccttcggaaccaccgg
cctcggacggcccagcgggctgctgctcaggttctgggaagttctggattgtttaataac
catggactccaagtacagcagcaacagcaaaggaatctctcactacatgaatacatgagt
atggaattattgcaagaagctggtgtctccgttcccaaaggatatgtggcaaagtcacca
gatgaagcttatgcaattgccaaaaaattaggttcaaaagatgtcgtgataaaggcacag
gttttagctggtggtagaggaaaaggaacatttgaaagtggcctcaaaggaggagtgaag
atagttttctctccagaagaagcaaaagctgtttcttcacaaatgattgggaaaaaattg
tttaccaagcaaacgggagaaaagggcagaatatgcaatcaagtattggtctgtgagcga
aaatatcccaggagagaatactactttgcaataacaatggaaaggtcatttcaaggtcct
gtattaataggaagttcacatggtggtgtcaacattgaagatgttgctgctgagtctcct
gaagcaataattaaagaacctattgatattgaagaaggcatcaaaaaggaacaagctctc
cagcttgcacagaagatgggatttccacctaatattgtggaatcagcagcagaaaacatg
gtcaagctttacagcctttttctgaaatacgatgcaaccatgatagaaataaatccaatg
gtggaagattcagatggagctgtattgtgtatggatgcaaagatcaattttgactctaat
tcagcctatcgccaaaagaaaatctttgatctacaggactggacccaggaagatgaaagg
gacaaagatgctgctaaggcaaatctcaactacattggcctcgatggaaatataggctgc
ctagtaaatggtgctggtttggctatggccacaatggatataataaaacttcatggaggg
actccagccaacttccttgatgttggtggtggtgctacagtccatcaagtaacagaagca
tttaagcttatcacttcagataaaaaggtactggctattctggtcaacatttttggagga
atcatgcgctgtgatgttattgcacagggtatagtcatggcagtaaaagacttggaaatt
aaaatacctgttgtggtacggttacaaggtacacgagtcgatgatgctaaggcactgata
gcggacagtggacttaaaatacttgcttgtgatgacttggatgaagctgctagaatggtt
gtaaagctctctgaaatagtgaccttagcgaagcaagcacatgtggatgtgaaatttcag
ttgccaatatga

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