KEGG   Homo sapiens (human): 8844
Entry
8844              CDS       T01001                                 

Gene name
KSR1, KSR, RSU2
Definition
(RefSeq) kinase suppressor of ras 1
  KO
K14958  kinase suppressor of Ras 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    8844 (KSR1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    8844 (KSR1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    8844 (KSR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8844 (KSR1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   8844 (KSR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Kinase-like RIO1 C1_1 Kdo APH FTA2 zf-RING-like
Other DBs
NCBI-GeneID: 8844
NCBI-ProteinID: NP_055053
OMIM: 601132
HGNC: 6465
Ensembl: ENSG00000141068
Vega: OTTHUMG00000132051
Pharos: Q8IVT5(Tbio)
UniProt: Q8IVT5
Structure
PDB: 
5VYK

Position
17q11.2
AA seq 762 aa
MNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPS
TDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHAS
GRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLG
NRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCR
LKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPP
AMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHR
QQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAH
EAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGE
PIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACM
NPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSK
NVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLP
FSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILS
ACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSAEL
NT seq 2289 nt   +upstreamnt  +downstreamnt
atgaatgaggccaaggtgaaggagacgctgcggcgctgtggggccagcggggatgagtgt
ggccgtctgcagtatgccctcacctgcctgcggaaggtgacaggcctgggaggggagcac
aaggaggactccagttggagttcattggatgcgcggcgggaaagtggctcagggccttcc
acggacaccctctcagcagccagcctgccctggcccccagggagctcccagctgggcaga
gcaggcaacagcgcccagggcccacgctccatctccgtgtcagctctgcccgcctcagac
tcccccacccccagcttcagtgagggcctctcagacacctgtattcccctgcacgccagc
ggccggctgaccccccgtgccctgcacagcttcatcaccccgcccaccacaccccagctg
cgacggcacaccaagctgaagccaccacggacgccccccccacccagccgcaaggtcttc
cagctgctgcccagcttccccacactcacccggagcaagtcccatgagtctcagctgggg
aaccgcattgatgacgtctcctcgatgaggtttgatctctcgcatggatccccacagatg
gtacggagggatatcgggctgtcggtgacgcacaggttctccaccaagtcctggctgtcg
caggtctgccacgtgtgccagaagagcatgatatttggagtgaagtgcaagcattgcagg
ttgaagtgtcacaacaaatgtaccaaagaagcccctgcctgtagaatatccttcctgcca
ctaactcggcttcggaggacagaatctgtcccctcggacatcaacaacccggtggacaga
gcagccgaaccccattttggaaccctccccaaagcactgacaaagaaggagcaccctccg
gccatgaatcacctggactccagcagcaacccttcctccaccacctcctccacaccctcc
tcaccggcgcccttcccgacatcatccaacccatccagcgccaccacgccccccaacccc
tcacctggccagcgggacagcaggttcaacttcccagctgcctacttcattcatcataga
cagcagtttatctttccagtgccatctgctggccattgctggaaatgcctccttattgca
gaaagtttaaaggaaaacgctttcaacatttcagcctttgcacacgcagccccgctccct
gaagctgccgacggtacccggctcgatgaccagccgaaagcagatgtgttggaagctcac
gaagcggaggctgaggagccagaggctggcaagtcagaggcagaagacgatgaggacgag
gtggacgacttgccgagctctcgccggccctggcggggccccatctctcgcaaggccagc
cagaccagcgtgtacctgcaggagtgggacatccccttcgagcaggtagagctgggcgag
cccatcgggcagggccgctggggccgggtgcaccgcggccgctggcatggcgaggtggcc
attcgcctgctggagatggacggccacaaccaggaccacctgaagctcttcaagaaagag
gtgatgaactaccggcagacgcggcatgagaacgtggtgctcttcatgggggcctgcatg
aacccgccccacctggccattatcaccagcttctgcaaggggcggacgttgcactcgttt
gtgagggaccccaagacgtctctggacatcaacaagacgaggcaaatcgctcaggagatc
atcaagggcatgggatatcttcatgccaagggcatcgtacacaaagatctcaaatctaag
aacgtcttctatgacaacggcaaggtggtcatcacagacttcgggctgtttgggatctca
ggcgtggtccgagagggacggcgtgagaaccagctaaagctgtcccacgactggctgtgc
tatctggcccctgagattgtacgcgagatgacccccgggaaggacgaggatcagctgcca
ttctccaaagctgctgatgtctatgcatttgggactgtttggtatgagctgcaagcaaga
gactggcccttgaagaaccaggctgcagaggcatccatctggcagattggaagcggggaa
ggaatgaagcgtgtcctgacttctgtcagcttggggaaggaagtcagtgagatcctgtcg
gcctgctgggctttcgacctgcaggagagacccagcttcagcctgctgatggacatgctg
gagaaacttcccaagctgaaccggcggctctcccaccctggacacttctggaagtcagct
gagttgtag

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