KEGG   Homo sapiens (human): 8844
Entry
8844              CDS       T01001                                 

Gene name
KSR1, KSR, RSU2
Definition
(RefSeq) kinase suppressor of ras 1
  KO
K14958  kinase suppressor of Ras 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    8844 (KSR1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    8844 (KSR1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    8844 (KSR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8844 (KSR1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   8844 (KSR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Kinase-like RIO1 C1_1 Kdo APH FTA2 zf-RING-like
Other DBs
NCBI-GeneID: 8844
NCBI-ProteinID: NP_055053
OMIM: 601132
HGNC: 6465
Ensembl: ENSG00000141068
Vega: OTTHUMG00000132051
Pharos: Q8IVT5(Tbio)
UniProt: Q8IVT5
Structure
PDB: 
5VYK

Position
17q11.2
AA seq 762 aa
MNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPS
TDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHAS
GRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLG
NRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCR
LKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPP
AMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHR
QQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAH
EAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQVELGE
PIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACM
NPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSK
NVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLP
FSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILS
ACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSAEL
NT seq 2289 nt   +upstreamnt  +downstreamnt
atgaatgaggccaaggtgaaggagacgctgcggcgctgtggggccagcggggatgagtgt
ggccgtctgcagtatgccctcacctgcctgcggaaggtgacaggcctgggaggggagcac
aaggaggactccagttggagttcattggatgcgcggcgggaaagtggctcagggccttcc
acggacaccctctcagcagccagcctgccctggcccccagggagctcccagctgggcaga
gcaggcaacagcgcccagggcccacgctccatctccgtgtcagctctgcccgcctcagac
tcccccacccccagcttcagtgagggcctctcagacacctgtattcccctgcacgccagc
ggccggctgaccccccgtgccctgcacagcttcatcaccccgcccaccacaccccagctg
cgacggcacaccaagctgaagccaccacggacgccccccccacccagccgcaaggtcttc
cagctgctgcccagcttccccacactcacccggagcaagtcccatgagtctcagctgggg
aaccgcattgatgacgtctcctcgatgaggtttgatctctcgcatggatccccacagatg
gtacggagggatatcgggctgtcggtgacgcacaggttctccaccaagtcctggctgtcg
caggtctgccacgtgtgccagaagagcatgatatttggagtgaagtgcaagcattgcagg
ttgaagtgtcacaacaaatgtaccaaagaagcccctgcctgtagaatatccttcctgcca
ctaactcggcttcggaggacagaatctgtcccctcggacatcaacaacccggtggacaga
gcagccgaaccccattttggaaccctccccaaagcactgacaaagaaggagcaccctccg
gccatgaatcacctggactccagcagcaacccttcctccaccacctcctccacaccctcc
tcaccggcgcccttcccgacatcatccaacccatccagcgccaccacgccccccaacccc
tcacctggccagcgggacagcaggttcaacttcccagctgcctacttcattcatcataga
cagcagtttatctttccagtgccatctgctggccattgctggaaatgcctccttattgca
gaaagtttaaaggaaaacgctttcaacatttcagcctttgcacacgcagccccgctccct
gaagctgccgacggtacccggctcgatgaccagccgaaagcagatgtgttggaagctcac
gaagcggaggctgaggagccagaggctggcaagtcagaggcagaagacgatgaggacgag
gtggacgacttgccgagctctcgccggccctggcggggccccatctctcgcaaggccagc
cagaccagcgtgtacctgcaggagtgggacatccccttcgagcaggtagagctgggcgag
cccatcgggcagggccgctggggccgggtgcaccgcggccgctggcatggcgaggtggcc
attcgcctgctggagatggacggccacaaccaggaccacctgaagctcttcaagaaagag
gtgatgaactaccggcagacgcggcatgagaacgtggtgctcttcatgggggcctgcatg
aacccgccccacctggccattatcaccagcttctgcaaggggcggacgttgcactcgttt
gtgagggaccccaagacgtctctggacatcaacaagacgaggcaaatcgctcaggagatc
atcaagggcatgggatatcttcatgccaagggcatcgtacacaaagatctcaaatctaag
aacgtcttctatgacaacggcaaggtggtcatcacagacttcgggctgtttgggatctca
ggcgtggtccgagagggacggcgtgagaaccagctaaagctgtcccacgactggctgtgc
tatctggcccctgagattgtacgcgagatgacccccgggaaggacgaggatcagctgcca
ttctccaaagctgctgatgtctatgcatttgggactgtttggtatgagctgcaagcaaga
gactggcccttgaagaaccaggctgcagaggcatccatctggcagattggaagcggggaa
ggaatgaagcgtgtcctgacttctgtcagcttggggaaggaagtcagtgagatcctgtcg
gcctgctgggctttcgacctgcaggagagacccagcttcagcctgctgatggacatgctg
gagaaacttcccaagctgaaccggcggctctcccaccctggacacttctggaagtcagct
gagttgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (20)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (39)   
   RefSeq(nuc) (21)   
   GenBank (9)   
   EMBL (9)   
Protein domain (9)   
   Pfam (9)   
All databases (101)   

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