KEGG   Homo sapiens (human): 8851
Entry
8851              CDS       T01001                                 
Symbol
CDK5R1, CDK5P35, CDK5R, NCK5A, p23, p25, p35, p35nck5a
Name
(RefSeq) cyclin dependent kinase 5 regulatory subunit 1
  KO
K11716  cyclin-dependent kinase 5 activator 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05030  Cocaine addiction
Network
nt06418  Oxidative phosphorylation
nt06419  Microtubule-based transport
nt06460  Alzheimer disease
  Element
N00997  Mutation-caused aberrant Abeta to electron transfer in Complex I
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    8851 (CDK5R1)
   05022 Pathways of neurodegeneration - multiple diseases
    8851 (CDK5R1)
  09165 Substance dependence
   05030 Cocaine addiction
    8851 (CDK5R1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    8851 (CDK5R1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    8851 (CDK5R1)
SSDB
Motif
Pfam: CDK5_activator MTBP_C
Other DBs
NCBI-GeneID: 8851
NCBI-ProteinID: NP_003876
OMIM: 603460
HGNC: 1775
Ensembl: ENSG00000176749
Pharos: Q15078(Tchem)
UniProt: Q15078 Q8N619
Structure
Position
17:32486993..32491253
AA seq 307 aa
MGTVLSLSPSYRKATLFEDGAATVGHYTAVQNSKNAKDKNLKRHSIISVLPWKRIVAVSA
KKKNSKKVQPNSSYQNNITHLNNENLKKSLSCANLSTFAQPPPAQPPAPPASQLSGSQTG
GSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRS
VDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNE
ISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKR
LLLGLDR
NT seq 924 nt   +upstreamnt  +downstreamnt
atgggcacggtgctgtccctgtctcccagctaccggaaggccacgctgtttgaggatggc
gcggccaccgtgggccactatacggccgtacagaacagcaagaacgccaaggacaagaac
ctgaagcgccactccatcatctccgtgctgccttggaagagaatcgtggccgtgtcggcc
aagaagaagaactccaagaaggtgcagcccaacagcagctaccagaacaacatcacgcac
ctcaacaatgagaacctgaagaagtcgctgtcgtgcgccaacctgtccacattcgcccag
cccccaccggcccagccgcctgcacccccggccagccagctctcgggttcccagaccggg
ggctcctcctcagtcaagaaagcccctcaccctgccgtcacctccgcagggacgcccaaa
cgggtcatcgtccaggcgtccaccagtgagctgcttcgctgcctgggtgagtttctctgc
cgccggtgctaccgcctgaagcacctgtcccccacggaccccgtgctctggctgcgcagc
gtggaccgctcgctgcttctgcagggctggcaggaccagggcttcatcacgccggccaac
gtggtcttcctctacatgctctgcagggatgttatctcctccgaggtgggctcggatcac
gagctccaggccgtcctgctgacatgcctgtacctctcctactcctacatgggcaacgag
atctcctacccgctcaagcccttcctggtggagagctgcaaggaggccttttgggaccgt
tgcctctctgtcatcaacctcatgagctcaaagatgctgcagataaatgccgacccacac
tacttcacacaggtcttctccgacctgaagaacgagagcggccaggaggacaagaagcgg
ctcctcctaggcctggatcggtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
3D Structure (11)   
   PDB (11)   
Protein domain (2)   
   Pfam (2)   
All databases (57)   

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