KEGG   Homo sapiens (human): 8851
Entry
8851              CDS       T01001                                 
Symbol
CDK5R1, CDK5P35, CDK5R, NCK5A, p23, p25, p35, p35nck5a
Name
(RefSeq) cyclin dependent kinase 5 regulatory subunit 1
  KO
K11716  cyclin-dependent kinase 5 activator 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05010  Alzheimer disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05030  Cocaine addiction
Network
nt06460  Alzheimer disease
nt06466  Pathways of neurodegeneration
nt06541  Cytoskeleton in neurons
  Element
N00997  Mutation-caused aberrant Abeta to electron transfer in Complex I
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01847  Regulation of dynein-mediated retrograde transport
N01857  SEMA3A-DCX axon guidance signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    8851 (CDK5R1)
   05022 Pathways of neurodegeneration - multiple diseases
    8851 (CDK5R1)
  09165 Substance dependence
   05030 Cocaine addiction
    8851 (CDK5R1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    8851 (CDK5R1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    8851 (CDK5R1)
SSDB
Motif
Pfam: CDK5_activator MTBP_C
Other DBs
NCBI-GeneID: 8851
NCBI-ProteinID: NP_003876
OMIM: 603460
HGNC: 1775
Ensembl: ENSG00000176749
UniProt: Q15078 Q8N619
Structure
Position
17:32486993..32491253
AA seq 307 aa
MGTVLSLSPSYRKATLFEDGAATVGHYTAVQNSKNAKDKNLKRHSIISVLPWKRIVAVSA
KKKNSKKVQPNSSYQNNITHLNNENLKKSLSCANLSTFAQPPPAQPPAPPASQLSGSQTG
GSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRS
VDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNE
ISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKR
LLLGLDR
NT seq 924 nt   +upstreamnt  +downstreamnt
atgggcacggtgctgtccctgtctcccagctaccggaaggccacgctgtttgaggatggc
gcggccaccgtgggccactatacggccgtacagaacagcaagaacgccaaggacaagaac
ctgaagcgccactccatcatctccgtgctgccttggaagagaatcgtggccgtgtcggcc
aagaagaagaactccaagaaggtgcagcccaacagcagctaccagaacaacatcacgcac
ctcaacaatgagaacctgaagaagtcgctgtcgtgcgccaacctgtccacattcgcccag
cccccaccggcccagccgcctgcacccccggccagccagctctcgggttcccagaccggg
ggctcctcctcagtcaagaaagcccctcaccctgccgtcacctccgcagggacgcccaaa
cgggtcatcgtccaggcgtccaccagtgagctgcttcgctgcctgggtgagtttctctgc
cgccggtgctaccgcctgaagcacctgtcccccacggaccccgtgctctggctgcgcagc
gtggaccgctcgctgcttctgcagggctggcaggaccagggcttcatcacgccggccaac
gtggtcttcctctacatgctctgcagggatgttatctcctccgaggtgggctcggatcac
gagctccaggccgtcctgctgacatgcctgtacctctcctactcctacatgggcaacgag
atctcctacccgctcaagcccttcctggtggagagctgcaaggaggccttttgggaccgt
tgcctctctgtcatcaacctcatgagctcaaagatgctgcagataaatgccgacccacac
tacttcacacaggtcttctccgacctgaagaacgagagcggccaggaggacaagaagcgg
ctcctcctaggcctggatcggtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (12)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
3D Structure (11)   
   PDB (11)   
Protein domain (2)   
   Pfam (2)   
All databases (47)   

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