KEGG   Homo sapiens (human): 8854Help
Entry
8854              CDS       T01001                                 

Gene name
ALDH1A2, RALDH(II), RALDH2, RALDH2-T
Definition
(RefSeq) aldehyde dehydrogenase 1 family member A2
  KO
K07249  retinal dehydrogenase [EC:1.2.1.36]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00830  Retinol metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    8854 (ALDH1A2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.36  retinal dehydrogenase
     8854 (ALDH1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Aldedh LuxC
Motif
Other DBs
NCBI-GeneID: 8854
NCBI-ProteinID: NP_003879
OMIM: 603687
HGNC: 15472
Ensembl: ENSG00000128918
Vega: OTTHUMG00000132624
Pharos: O94788(Tbio)
UniProt: O94788
Structure
PDB: 

Position
15q21.3
AA seq 518 aa AA seqDB search
MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP
ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL
ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP
GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
NT seq 1557 nt NT seq  +upstreamnt  +downstreamnt
atgacttccagcaagatagagatgcccggcgaggtgaaggccgaccccgccgccctcatg
gcgtcgctgcacctcctgccgtcgcccacgcccaatctcgaaattaagtacaccaagatc
tttataaacaacgagtggcagaactcagagagtgggagagtgttccctgtctataatcca
gccacaggagaacaggtgtgtgaagttcaagaagcagacaaggcagatatagacaaagca
gtgcaggcagcccgcctggctttctctcttggttcagtgtggagaaggatggatgcttca
gaaaggggacgtctgttggataagcttgcagacttggtggaacgggacagggcagttctt
gcaaccatggaatccctaaatggtggcaaaccattcctgcaagctttttatgtggatttg
cagggcgtcatcaaaacctttcgatattacgcaggctgggctgataaaattcatgggatg
accattcctgtagatggagactattttacctttacaagacatgaacccattggagtgtgt
ggacagatcatcccatggaacttccccctgctgatgtttgcctggaaaatagctccagct
ttgtgctgtggcaatacagtagttattaagccagcagagcaaacaccactcagtgcactc
tacatgggagccctcatcaaggaggctggctttcctcccggggtcatcaatattttgcca
ggatatgggccaacggctggggcagcaatagcttctcacattggcatagacaagattgca
ttcacagggtctactgaggttggaaagcttatccaagaagcagctggaagaagtaatttg
aagagagtaactctggaacttggaggcaaaagtcctaatattatttttgctgatgctgac
ttggactatgctgtggagcaggcccaccagggtgtgttcttcaatcaaggtcagtgctgc
actgcaggctctcgcatcttcgtggaggagtccatctatgaggagtttgtgagaagaagc
gtggagcgggccaagaggcgcgtagtggggagtccctttgaccccaccactgagcagggt
ccccagattgataagaaacagtacaacaagatcttggaactcatccagagtggtgtggct
gagggcgccaagctggaatgtggaggcaaaggactgggccgaaaggggtttttcattgag
cccacagtgttttccaacgtcactgatgatatgcggattgccaaggaggagatctttggc
cctgttcaggaaattttgagatttaagacgatggatgaagttatcgaaagagccaataac
tcagactttggactcgtagcagctgtctttactaatgacatcaacaaggccctcacagtg
tcttctgcaatgcaagctgggactgtttggatcaattgttacaatgccttaaatgcccag
agcccctttgggggattcaagatgtctggaaatgggagagaaatgggagaatttggcttg
cgggagtactcagaagttaagacggtgacagtaaagatcccccagaagaactcctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (33)   
   RefSeq(nuc) (5)   
   GenBank (14)   
   EMBL (14)   
Protein domain (2)   
   Pfam (2)   
All databases (71)   

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