KEGG   Homo sapiens (human): 8854
Entry
8854              CDS       T01001                                 
Symbol
ALDH1A2, DIH4, RALDH(II), RALDH2, RALDH2-T
Name
(RefSeq) aldehyde dehydrogenase 1 family member A2
  KO
K07249  retinal dehydrogenase [EC:1.2.1.36]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00830  Retinol metabolism
hsa01100  Metabolic pathways
Disease
H01241  Congenital diaphragmatic hernia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    8854 (ALDH1A2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.36  retinal dehydrogenase
     8854 (ALDH1A2)
SSDB
Motif
Pfam: Aldedh LuxC Methyltransf_33
Other DBs
NCBI-GeneID: 8854
NCBI-ProteinID: NP_003879
OMIM: 603687
HGNC: 15472
Ensembl: ENSG00000128918
UniProt: O94788
Structure
Position
15:complement(57953429..58065711)
AA seq 518 aa
MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP
ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL
ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP
GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
NT seq 1557 nt   +upstreamnt  +downstreamnt
atgacttccagcaagatagagatgcccggcgaggtgaaggccgaccccgccgccctcatg
gcgtcgctgcacctcctgccgtcgcccacgcccaatctcgaaattaagtacaccaagatc
tttataaacaacgagtggcagaactcagagagtgggagagtgttccctgtctataatcca
gccacaggagaacaggtgtgtgaagttcaagaagcagacaaggcagatatagacaaagca
gtgcaggcagcccgcctggctttctctcttggttcagtgtggagaaggatggatgcttca
gaaaggggacgtctgttggataagcttgcagacttggtggaacgggacagggcagttctt
gcaaccatggaatccctaaatggtggcaaaccattcctgcaagctttttatgtggatttg
cagggcgtcatcaaaacctttcgatattacgcaggctgggctgataaaattcatgggatg
accattcctgtagatggagactattttacctttacaagacatgaacccattggagtgtgt
ggacagatcatcccatggaacttccccctgctgatgtttgcctggaaaatagctccagct
ttgtgctgtggcaatacagtagttattaagccagcagagcaaacaccactcagtgcactc
tacatgggagccctcatcaaggaggctggctttcctcccggggtcatcaatattttgcca
ggatatgggccaacggctggggcagcaatagcttctcacattggcatagacaagattgca
ttcacagggtctactgaggttggaaagcttatccaagaagcagctggaagaagtaatttg
aagagagtaactctggaacttggaggcaaaagtcctaatattatttttgctgatgctgac
ttggactatgctgtggagcaggcccaccagggtgtgttcttcaatcaaggtcagtgctgc
actgcaggctctcgcatcttcgtggaggagtccatctatgaggagtttgtgagaagaagc
gtggagcgggccaagaggcgcgtagtggggagtccctttgaccccaccactgagcagggt
ccccagattgataagaaacagtacaacaagatcttggaactcatccagagtggtgtggct
gagggcgccaagctggaatgtggaggcaaaggactgggccgaaaggggtttttcattgag
cccacagtgttttccaacgtcactgatgatatgcggattgccaaggaggagatctttggc
cctgttcaggaaattttgagatttaagacgatggatgaagttatcgaaagagccaataac
tcagactttggactcgtagcagctgtctttactaatgacatcaacaaggccctcacagtg
tcttctgcaatgcaagctgggactgtttggatcaattgttacaatgccttaaatgcccag
agcccctttgggggattcaagatgtctggaaatgggagagaaatgggagaatttggcttg
cgggagtactcagaagttaagacggtgacagtaaagatcccccagaagaactcctaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (8)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (32)   
   RefSeq(nuc) (4)   
   GenBank (14)   
   EMBL (14)   
3D Structure (5)   
   PDB (5)   
Protein domain (3)   
   Pfam (3)   
All databases (56)   

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