KEGG   Homo sapiens (human): 886Help
Entry
886               CDS       T01001                                 

Gene name
CCKAR, CCK-A, CCK1-R, CCK1R, CCKRA
Definition
(RefSeq) cholecystokinin A receptor
  KO
K04194  cholecystokinin A receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
hsa04972  Pancreatic secretion
Drug target
Ceruletide (DG01165): D03442 D03443
Devazepide: D02693
Loxiglumide: D01113
Panazepide: D01858
Tarazepide: D02710
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    886 (CCKAR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    886 (CCKAR)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    886 (CCKAR)
  09154 Digestive system
   04972 Pancreatic secretion
    886 (CCKAR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    886 (CCKAR)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Cholecystokinin
    886 (CCKAR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 CholecysA-Rec_N 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID: 886
NCBI-ProteinID: NP_000721
OMIM: 118444
HGNC: 1570
Ensembl: ENSG00000163394
Vega: OTTHUMG00000128567
Pharos: P32238(Tclin)
UniProt: P32238
Position
4p15.2
AA seq 428 aa AA seqDB search
MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
MSASVPPQ
NT seq 1287 nt NT seq  +upstreamnt  +downstreamnt
atggatgtggttgacagccttcttgtgaatggaagcaacatcactcctccctgtgaactc
gggctcgaaaatgagacgcttttctgcttggatcagccccgtccttccaaagagtggcag
ccagcggtgcagattctcttgtactccttgatattcctgctcagcgtgctgggaaacacg
ctggtcatcaccgtgctgattcggaacaagcggatgcggacggtcaccaacatcttcctc
ctctccctggctgtcagcgacctcatgctctgtctcttctgcatgccgttcaacctcatc
cccaatctgctcaaggatttcatcttcgggagcgccgtttgcaagaccaccacctacttc
atgggcacctctgtgagtgtatctacctttaatctggtagccatatctctagagagatat
ggtgcgatttgcaaacccttacagtcccgggtctggcagacaaaatcccatgctttgaag
gtgattgctgctacctggtgcctttcctttaccatcatgactccgtaccccatttatagc
aacttggtgccttttaccaaaaataacaaccagaccgcgaatatgtgccgctttctactg
ccaaatgatgttatgcagcagtcctggcacacattcctgttactcatcctctttcttatt
cctggaattgtgatgatggtggcatatggattaatctctttggaactctaccagggaata
aaatttgaggctagccagaagaagtctgctaaagaaaggaaacctagcaccaccagcagc
ggcaaatatgaggacagcgatgggtgttacctgcaaaagaccaggcccccgaggaagctg
gagctccggcagctgtccaccggcagcagcagcagggccaaccgcatccggagtaacagc
tccgcagccaacctgatggccaagaaaagggtgatccgcatgctcatcgtcatcgtggtc
ctcttcttcctgtgctggatgcccatcttcagcgccaacgcctggcgggcctacgacacc
gcctccgcagagcgccgcctctcaggaacccccatttccttcatcctcctcctgtcctac
acctcctcctgcgtcaaccccatcatctactgcttcatgaacaaacgcttccgcctcggc
ttcatggccaccttcccctgctgccccaatcctggtcccccaggggcgaggggagaggtg
ggggaggaggaggaaggcgggaccacaggagcctctctgtccaggttctcgtacagccat
atgagtgcctcggtgccaccccagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (5)   
   Pfam (5)   
All databases (42)   

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KEGG   Homo sapiens (human): 887Help
Entry
887               CDS       T01001                                 

Gene name
CCKBR, CCK-B, CCK2R, GASR
Definition
(RefSeq) cholecystokinin B receptor
  KO
K04195  cholecystokinin B receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04971  Gastric acid secretion
Drug target
Panazepide: D01858
Pentagastrin: D01631
Proglumide: D01818
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    887 (CCKBR)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    887 (CCKBR)
 09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    887 (CCKBR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    887 (CCKBR)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Cholecystokinin
    887 (CCKBR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID: 887
NCBI-ProteinID: NP_795344
OMIM: 118445
HGNC: 1571
Ensembl: ENSG00000110148
Vega: OTTHUMG00000133380
Pharos: P32239(Tclin)
UniProt: P32239
Position
11p15.4
AA seq 447 aa AA seqDB search
MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
PDEDPPTPSIASLSRLSYTTISTLGPG
NT seq 1344 nt NT seq  +upstreamnt  +downstreamnt
atggagctgctaaagctgaaccggagcgtgcagggaaccggacccgggccgggggcttcc
ctgtgccgcccgggggcgcctctcctcaacagcagcagtgtgggcaacctcagctgcgag
ccccctcgcattcgcggagccgggacacgagaattggagctggccattagaatcactctt
tacgcagtgatcttcctgatgagcgttggaggaaatatgctcatcatcgtggtcctggga
ctgagccgccgcctgaggactgtcaccaatgccttcctcctctcactggcagtcagcgac
ctcctgctggctgtggcttgcatgcccttcaccctcctgcccaatctcatgggcacattc
atctttggcaccgtcatctgcaaggcggtttcctacctcatgggggtgtctgtgagtgtg
tccacgctaagcctcgtggccatcgcactggagcggtacagcgccatctgccgaccactg
caggcacgagtgtggcagacgcgctcccacgcggctcgcgtgattgtagccacgtggctg
ctgtccggactactcatggtgccctaccccgtgtacactgtcgtgcaaccagtggggcct
cgtgtgctgcagtgcgtgcatcgctggcccagtgcgcgggtccgccagacctggtccgta
ctgctgcttctgctcttgttcttcatcccgggtgtggttatggccgtggcctacgggctt
atctctcgcgagctctacttagggcttcgctttgacggcgacagtgacagcgacagccaa
agcagggtccgaaaccaaggcgggctgccaggggctgttcaccagaacgggcgttgccgg
cctgagactggcgcggttggcgaagacagcgatggctgctacgtgcaacttccacgttcc
cggcctgccctggagctgacggcgctgacggctcctgggccgggatccggctcccggccc
acccaggccaagctgctggctaagaagcgcgtggtgcgaatgttgctggtgatcgttgtg
cttttttttctgtgttggttgccagtttatagtgccaacacgtggcgcgcctttgatggc
ccgggtgcacaccgagcactctcgggtgctcctatctccttcattcacttgctgagctac
gcctcggcctgtgtcaaccccctggtctactgcttcatgcaccgtcgctttcgccaggcc
tgcctggaaacttgcgctcgctgctgcccccggcctccacgagctcgccccagggctctt
cccgatgaggaccctcccactccctccattgcttcgctgtccaggcttagctacaccacc
atcagcacactgggccctggctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (50)   
   RefSeq(nuc) (4)   
   GenBank (23)   
   EMBL (23)   
Protein domain (4)   
   Pfam (4)   
All databases (91)   

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