KEGG   Homo sapiens (human): 8887
Entry
8887              CDS       T01001                                 
Symbol
TAX1BP1, CALCOCO3, T6BP, TXBP151
Name
(RefSeq) Tax1 binding protein 1
  KO
K21347  Tax1-binding protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
hsa04140  Autophagy - animal
Network
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06532  Autophagy
nt06536  Mitophagy
  Element
N01137  PINK-Parkin-mediated autophagosome formation
N01140  TBK1-mediated autophagosome formation
N01141  Mutation-inactivated TBK1 to TBK1-mediated autophagosome formation
N01716  Autophagy-vesicle nucleation/elongation/maturation, sequestosome-1-like receptor
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    8887 (TAX1BP1)
   04137 Mitophagy - animal
    8887 (TAX1BP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    8887 (TAX1BP1)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    8887 (TAX1BP1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    8887 (TAX1BP1)
  Xenophagy
   Cargo receptors
    8887 (TAX1BP1)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    8887 (TAX1BP1)
SSDB
Motif
Pfam: SKICH CALCOCO1 Zn-C2H2_12 UBZ_FAAP20
Other DBs
NCBI-GeneID: 8887
NCBI-ProteinID: NP_006015
OMIM: 605326
HGNC: 11575
Ensembl: ENSG00000106052
UniProt: Q86VP1
Structure
Position
7:27739373..27829767
AA seq 789 aa
MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHPKDWVGIFKVGWSTA
RDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQF
RASSPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLRE
QVGRMERELNHEKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVS
VTHKAIEKETELDSLKDKLKKAQHEREQLECQLKTEKDEKELYKVHLKNTEIENTKLMSE
VQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTCFLKEQLRKAE
EQVQATRQEVVFLAKELSDAVNVRDRTMADLHTARLENEKVKKQLADAVAELKLNAMKKD
QDKTDTLEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSANNNNVFTKK
TGNQQKVNDASVNTDPATSASTVDVKPSPSAAEADFDIVTKGQVCEMTKEIADKTEKYNK
CKQLLQDEKAKCNKYADELAKMELKWKEQVKIAENVKLELAEVQDNYKELKRSLENPAER
KMEGQNSQSPQCFKTCSEQNGYVLTLSNAQPVLQYGNPYASQETRDGADGAFYPDEIQRP
PVRVPSWGLEDNVVCSQPARNFSRPDGLEDSEDSKEDENVPTAPDPPSQHLRGHGTGFCF
DSSFDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTH
FDQNVLNFD
NT seq 2370 nt   +upstreamnt  +downstreamnt
atgacatcctttcaagaagtcccattgcagacttccaactttgcccatgtcatctttcaa
aatgtggccaagagttaccttcctaatgcacacctggaatgtcattacaccttaactcca
tatattcatccacatccaaaagattgggttggtatattcaaggttggatggagtactgct
cgtgattattacacgtttttatggtcccctatgcctgaacattatgtggaaggatcaaca
gtcaattgtgtactagcattccaaggatattaccttccaaatgatgatggagaattttat
cagttctgttacgttacccataagggtgaaattcgtggagcaagtacacctttccagttt
cgagcttcttctccagttgaagagctgcttactatggaagatgaaggaaattctgacatg
ttagtggtgaccacaaaagcaggccttcttgagttgaaaattgagaaaaccatgaaagaa
aaagaagaactgttaaagttaattgccgttctggaaaaagaaacagcacaacttcgagaa
caagttgggagaatggaaagagaacttaaccatgagaaagaaagatgtgaccaactgcaa
gcagaacaaaagggtcttactgaagtaacacaaagcttaaaaatggaaaatgaagagttt
aagaagaggttcagtgatgctacatccaaagcccatcagcttgaggaagatattgtgtca
gtaacacataaagcaattgaaaaagaaaccgaattagacagtttaaaggacaaactcaag
aaggcacaacatgaaagagaacaacttgaatgtcagttgaagacagagaaggatgaaaag
gaactttataaggtacatttgaagaatacagaaatagaaaataccaagcttatgtcagag
gtccagactttaaaaaatttagatgggaacaaagaaagcgtgattactcatttcaaagaa
gagattggcaggctgcagttatgtttggctgaaaaggaaaatctgcaaagaactttcctg
cttacaacctcaagtaaagaagatacttgttttttaaaggagcaacttcgtaaagcagag
gaacaggttcaggcaactcggcaagaagttgtctttctggctaaagaactcagtgatgct
gtcaacgtacgagacagaacgatggcagacctgcatactgcacgcttggaaaacgagaaa
gtgaaaaagcagttagctgatgcagtggcagaacttaaactaaatgctatgaaaaaagat
caggacaagactgatacactggaacacgaactaagaagagaagttgaagatctgaaactc
cgtcttcagatggctgcagaccattataaagaaaaatttaaggaatgccaaaggctccaa
aaacaaataaacaaactttcagatcaatcagctaataataataatgtcttcacaaagaaa
acggggaatcagcagaaagtgaatgatgcttcagtaaacacagacccagccacttctgcc
tctactgtagatgtaaagccatcaccttctgcagcagaggcagattttgacatagtaaca
aaggggcaagtctgtgaaatgaccaaagaaattgctgacaaaacagaaaagtataataaa
tgtaaacaactcttgcaggatgagaaagcaaaatgcaataaatatgctgatgaacttgca
aaaatggagctgaaatggaaagaacaagtgaaaattgctgaaaatgtaaaacttgaacta
gctgaagtacaggacaattataaagaacttaaaaggagtctagaaaatccagcagaaagg
aaaatggaaggtcagaattcccagagtcctcaatgtttcaaaacatgctcagagcaaaat
ggttatgttctcacattgtcaaatgcacaaccagttctgcaatatggtaatccttatgca
tctcaggaaacaagagatggagcagatggtgctttttacccagatgaaatacaaaggcca
cctgtcagagtcccctcttggggactggaagacaatgttgtctgcagccagcctgctcga
aactttagtcggcctgatggcttagaggactctgaggatagcaaagaagatgagaatgtg
cctactgctcctgatcctccaagtcaacatttacgtgggcatgggacaggcttttgcttt
gattccagctttgatgttcacaagaagtgtcccctctgtgagttaatgtttcctcctaac
tatgatcagagcaaatttgaagaacatgttgaaagtcactggaaggtgtgcccgatgtgc
agcgagcagttccctcctgactatgaccagcaggtgtttgaaaggcatgtgcagacccat
tttgatcagaatgttctaaattttgactag

  All links  
Disease (1)   
   OMIM (1)   
Gene (23)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (66)   
   RefSeq(nuc) (6)   
   GenBank (30)   
   EMBL (30)   
3D Structure (10)   
   PDB (10)   
Protein domain (4)   
   Pfam (4)   
All databases (112)   

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