KEGG   Homo sapiens (human): 8890
Entry
8890              CDS       T01001                                 
Symbol
EIF2B4, EIF-2B, EIF2B, EIF2Bdelta, VWM4
Name
(RefSeq) eukaryotic translation initiation factor 2B subunit delta
  KO
K03680  translation initiation factor eIF-2B subunit delta
Organism
hsa  Homo sapiens (human)
Pathway
hsa05168  Herpes simplex virus 1 infection
Network
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
  Element
N00571  PKR-eIF2alpha signaling pathway
Disease
H00869  Leukoencephalopathy with vanishing white matter
Drug target
Fosigotifator (DG03349): D13118 D13119
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    8890 (EIF2B4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:hsa03012]
    8890 (EIF2B4)
Translation factors [BR:hsa03012]
 Eukaryotic type
  Initiation factors
   eIF-2B
    8890 (EIF2B4)
SSDB
Motif
Pfam: IF-2B
Other DBs
NCBI-GeneID: 8890
NCBI-ProteinID: NP_001029288
OMIM: 606687
HGNC: 3260
Ensembl: ENSG00000115211
UniProt: Q9UI10
Structure
Position
2:complement(27364352..27370338)
AA seq 523 aa
MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
NT seq 1572 nt   +upstreamnt  +downstreamnt
atggctgctgtggccgtggctgttcgcgaggactcgggatccgggatgaaggcggagctt
ccccctgggcctggggcagtggggagggaaatgaccaaagaagaaaagctgcagcttcgg
aaggaaaagaaacagcagaagaagaaacggaaggaagaaaagggggcagaaccagagact
ggctctgctgtatctgcagcccaatgtcaagtaggcccaaccagagaactgccagaatcg
ggcattcagttgggcactcctcgggagaaagttccagctggtcggagtaaggccgaactt
cgggctgagcgtcgagccaagcaggaggccgagcgggccctgaaacaggcaagaaaaggg
gaacaaggaggaccacctcctaaggccagccccagcacagctggagaaaccccctcagga
gtgaagcgtctccctgagtaccctcaggttgatgacctacttctgagaaggcttgttaaa
aaaccagagcgtcaacaggttcctacacgaaaggattatggatccaaagtcagtctcttc
tctcacctaccccagtacagcagacaaaactctctgacccagtttatgagcatcccatcc
tctgtgatccacccagccatggtgcgactcggcctgcagtactcccagggcctggtcagt
ggctccaatgcccggtgtattgccctgcttcgtgccttgcagcaggtgattcaggattac
acaacaccgcctaatgaagaactctccagggatctagtgaataaactaaaaccctacatg
agcttcctgactcagtgccgtcccctgtcagcgagcatgcacaacgccatcaagttcctt
aacaaggaaatcaccagtgtgggcagttccaagcgggaagaggaggccaagtcagaactt
cgagcagccattgatcggtatgtgcaagagaagattgtgctagcagctcaggcaatttca
cgctttgcttaccagaagatcagtaatggagatgtgatcctggtatatggatgctcatct
ctggtatcacgaattcttcaggaggcttggacagagggccggcggtttcgggtggtagtg
gtggacagccggccatggctggaaggaaggcacacactacgttctctagtccatgctggt
gtcccagcctcctacctgctgattcctgcagcctcctatgtgctcccagaggtttccaag
gtgctattgggagctcatgcactcttggccaacgggtctgtgatgtcacgggtagggaca
gcacagttagccctggtggctcgagcccataatgtaccagtgctggtttgctgtgaaaca
tacaagttctgtgagcgtgtgcagactgatgcctttgtctctaatgagctagatgaccct
gatgatctgcaatgtaagcggggagaacatgttgcgctggctaactggcagaaccacgca
tccctacggttgttgaatctagtctatgatgtgactcccccagagcttgtggatctggtg
atcacggagctggggatgatcccttgcagttctgtacctgttgttctacgagtcaagagc
agtgaccagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (25)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (36)   
   RefSeq(nuc) (8)   
   GenBank (14)   
   EMBL (14)   
3D Structure (22)   
   PDB (22)   
Protein domain (1)   
   Pfam (1)   
All databases (96)   

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