KEGG   Homo sapiens (human): 8890Help
Entry
8890              CDS       T01001                                 

Gene name
EIF2B4, EIF-2B, EIF2B, EIF2Bdelta
Definition
(RefSeq) eukaryotic translation initiation factor 2B subunit delta
  KO
K03680  translation initiation factor eIF-2B subunit delta
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  RNA transport
hsa05168  Herpes simplex virus 1 infection
Network
nt06138  PKR-eIF2alpha signaling (virus)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
  Element
N00571  PKR-eIF2alpha signaling pathway
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
N00573  HSV US11 to PKR-eIF2alpha signaling pathway
Disease
H00869  Leukoencephalopathy with vanishing white matter
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    8890 (EIF2B4)
 09160 Human Diseases
  09172 Infectious diseases: Viral
   05168 Herpes simplex virus 1 infection
    8890 (EIF2B4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:hsa03012]
    8890 (EIF2B4)
Translation factors [BR:hsa03012]
 Eukaryotic Type
  Initiation factors
   eIF-2B
    8890 (EIF2B4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: IF-2B DUF3819
Motif
Other DBs
NCBI-GeneID: 8890
NCBI-ProteinID: NP_001029288
OMIM: 606687
HGNC: 3260
Ensembl: ENSG00000115211
Vega: OTTHUMG00000151927
Pharos: Q9UI10(Tbio)
UniProt: Q9UI10
Structure
PDB: 

Position
2p23.3
AA seq 523 aa AA seqDB search
MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
NT seq 1572 nt NT seq  +upstreamnt  +downstreamnt
atggctgctgtggccgtggctgttcgcgaggactcgggatccgggatgaaggcggagctt
ccccctgggcctggggcagtggggagggaaatgaccaaagaagaaaagctgcagcttcgg
aaggaaaagaaacagcagaagaagaaacggaaggaagaaaagggggcagaaccagagact
ggctctgctgtatctgcagcccaatgtcaagtaggcccaaccagagaactgccagaatcg
ggcattcagttgggcactcctcgggagaaagttccagctggtcggagtaaggccgaactt
cgggctgagcgtcgagccaagcaggaggccgagcgggccctgaaacaggcaagaaaaggg
gaacaaggaggaccacctcctaaggccagccccagcacagctggagaaaccccctcagga
gtgaagcgtctccctgagtaccctcaggttgatgacctacttctgagaaggcttgttaaa
aaaccagagcgtcaacaggttcctacacgaaaggattatggatccaaagtcagtctcttc
tctcacctaccccagtacagcagacaaaactctctgacccagtttatgagcatcccatcc
tctgtgatccacccagccatggtgcgactcggcctgcagtactcccagggcctggtcagt
ggctccaatgcccggtgtattgccctgcttcgtgccttgcagcaggtgattcaggattac
acaacaccgcctaatgaagaactctccagggatctagtgaataaactaaaaccctacatg
agcttcctgactcagtgccgtcccctgtcagcgagcatgcacaacgccatcaagttcctt
aacaaggaaatcaccagtgtgggcagttccaagcgggaagaggaggccaagtcagaactt
cgagcagccattgatcggtatgtgcaagagaagattgtgctagcagctcaggcaatttca
cgctttgcttaccagaagatcagtaatggagatgtgatcctggtatatggatgctcatct
ctggtatcacgaattcttcaggaggcttggacagagggccggcggtttcgggtggtagtg
gtggacagccggccatggctggaaggaaggcacacactacgttctctagtccatgctggt
gtcccagcctcctacctgctgattcctgcagcctcctatgtgctcccagaggtttccaag
gtgctattgggagctcatgcactcttggccaacgggtctgtgatgtcacgggtagggaca
gcacagttagccctggtggctcgagcccataatgtaccagtgctggtttgctgtgaaaca
tacaagttctgtgagcgtgtgcagactgatgcctttgtctctaatgagctagatgaccct
gatgatctgcaatgtaagcggggagaacatgttgcgctggctaactggcagaaccacgca
tccctacggttgttgaatctagtctatgatgtgactcccccagagcttgtggatctggtg
atcacggagctggggatgatcccttgcagttctgtacctgttgttctacgagtcaagagc
agtgaccagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (38)   
   RefSeq(nuc) (10)   
   GenBank (14)   
   EMBL (14)   
Protein domain (2)   
   Pfam (2)   
All databases (92)   

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