KEGG   Homo sapiens (human): 8892Help
Entry
8892              CDS       T01001                                 

Gene name
EIF2B2, EIF-2Bbeta, EIF2B
Definition
(RefSeq) eukaryotic translation initiation factor 2B subunit beta
  KO
K03754  translation initiation factor eIF-2B subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  RNA transport
hsa05168  Herpes simplex virus 1 infection
Network
nt06138  PKR-eIF2alpha signaling (viruses)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
  Element
N00571  PKR-eIF2alpha signaling pathway
N00572  HSV ICP34.5 to PKR-eIF2alpha signaling pathway
N00573  HSV US11 to PKR-eIF2alpha signaling pathway
Disease
H00869  Leukoencephalopathy with vanishing white matter
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    8892 (EIF2B2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    8892 (EIF2B2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:hsa03012]
    8892 (EIF2B2)
Translation factors [BR:hsa03012]
 Eukaryotic type
  Initiation factors
   eIF-2B
    8892 (EIF2B2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: IF-2B DUF4055 MSC
Motif
Other DBs
NCBI-GeneID: 8892
NCBI-ProteinID: NP_055054
OMIM: 606454
HGNC: 3258
Ensembl: ENSG00000119718
Vega: OTTHUMG00000171764
Pharos: P49770(Tbio)
UniProt: P49770 Q53XC2
Structure
PDB: 

Position
14q24.3
AA seq 351 aa AA seqDB search
MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL
IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE
DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE
AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL
ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG
DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL
NT seq 1056 nt NT seq  +upstreamnt  +downstreamnt
atgccgggatccgcagcgaagggctcggagttgtcagagaggatcgagagcttcgtggag
accctgaagcggggtggtgggccgcgcagctccgaggaaatggctcgggagaccctaggg
ttgctgcgccagatcatcacggaccaccgctggagcaacgcgggggagctgatggagctg
atccgcagagagggcaggaggatgacggccgctcagccctccgagaccaccgtgggcaac
atggtgcggagagtgctcaagattatccgggaggagtatggcagactccatggacgcagc
gacgagagtgatcagcaggagtccctgcacaaactgttgacatccggaggcctaaacgag
gatttcagcttccattatgcccaactccagtccaacatcattgaggcgattaatgagctg
ctagtggagctggaagggacaatggagaacattgcagcccaggctctggagcacattcac
tccaatgaggtgatcatgaccattggcttctcccgaacagtagaggccttcctcaaagag
gctgcccgaaagaggaaattccatgtcattgtagcagagtgtgctcctttctgccagggt
catgaaatggctgtgaatttgtccaaagcaggtattgagacaactgtcatgactgatgct
gccatttttgccgttatgtcaagagtcaacaaggtgatcattggcacgaagaccatcctg
gccaatggggccctgagagctgtgacaggaactcacactctggcactggcagcaaaacac
cattccaccccactcatcgtctgtgcacctatgttcaaactttctccacagttccccaat
gaagaagactcatttcataagtttgtggctcctgaagaagtcctgccattcacagaaggg
gacattctggagaaggtcagcgtgcattgccctgtgtttgactacgttcccccagagctc
attaccctctttatctccaacattggtgggaatgcaccttcctacatctaccgcctgatg
agtgaactctaccatcctgatgatcatgttttatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (3)   
   Pfam (3)   
All databases (49)   

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