KEGG   Homo sapiens (human): 8893
Entry
8893              CDS       T01001                                 
Symbol
EIF2B5, CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM, VWM5
Name
(RefSeq) eukaryotic translation initiation factor 2B subunit epsilon
  KO
K03240  translation initiation factor eIF-2B subunit epsilon
Organism
hsa  Homo sapiens (human)
Pathway
hsa05168  Herpes simplex virus 1 infection
Network
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
  Element
N00571  PKR-eIF2alpha signaling pathway
Disease
H00869  Leukoencephalopathy with vanishing white matter
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    8893 (EIF2B5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:hsa03012]
    8893 (EIF2B5)
Translation factors [BR:hsa03012]
 Eukaryotic type
  Initiation factors
   eIF-2B
    8893 (EIF2B5)
SSDB
Motif
Pfam: W2 Hexapep Hexapep_2 DUF4954 Fucokinase
Other DBs
NCBI-GeneID: 8893
NCBI-ProteinID: NP_003898
OMIM: 603945
HGNC: 3261
Ensembl: ENSG00000145191
UniProt: Q13144
Structure
Position
3:184135358..184145311
AA seq 721 aa
MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS
KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV
RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV
MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV
RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV
SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV
LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK
ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM
KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS
RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV
LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG
ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED
D
NT seq 2166 nt   +upstreamnt  +downstreamnt
atggcggcccctgtagtggcgccgcctggtgtggtggttagtcgggctaacaagcgcagc
ggcgcggggccgggaggcagcggtggcgggggagccagaggggcggaggaggaaccgccg
ccgcccctacaagcagttctggtggccgatagcttcgatcgccgcttcttccccatctcc
aaggaccagcctcgggtcctcttgcccctggccaatgtggcattaattgactacactctg
gaattcctgactgccacaggtgtacaggaaacatttgtcttttgttgctggaaagctgct
caaatcaaagaacatttactgaagtcaaagtggtgccgccctacatctctcaatgtggtt
cgaataattacatcagagctctatcgatcactgggagatgtcctccgtgatgttgatgcc
aaggctttggtgcgctctgactttcttctggtgtatggggatgtcatctcaaacatcaat
atcaccagagcccttgaggaacacaggttgagacggaagctagaaaaaaatgtttctgtg
atgacgatgatcttcaaggagtcatcccccagccacccaactcgttgccacgaagacaat
gtggtagtggctgtggatagtaccacaaacagggttctccattttcagaagacccagggt
ctccggcgttttgcatttcctctgagcctgtttcagggcagtagtgatggagtggaggtt
cgatatgatttactggattgtcatatcagcatctgttctcctcaggtggcacaactcttt
acagacaactttgactaccaaactcgagatgactttgtgcgaggtctcttagtgaatgag
gagatcctagggaaccagatccacatgcacgtaacagctaaggaatatggtgcccgtgtc
tccaacctacacatgtactcagctgtctgtgctgacgtcatccgccgatgggtctaccct
ctcaccccagaggcgaacttcactgacagcaccacccagagctgcactcattcccggcac
aacatctaccgagggcctgaggtcagcctgggccatggcagcatcctagaggaaaatgtg
ctcctgggctctggcactgtcattggcagcaattgctttatcaccaacagtgtcattggc
cccggctgccacattggtgataacgtggtgctggaccagacctacctgtggcagggtgtt
cgagtggcggctggagcacagatccatcagtctctgctttgtgacaatgctgaggtcaag
gaacgagtgacactgaaaccacgctctgtcctcacttcccaggtggtcgtgggcccaaat
atcacgctgcctgagggctcggtgatctctttgcaccctccagatgcagaggaagatgaa
gatgatggcgagttcagtgatgattctggggctgaccaagaaaaggacaaagtgaagatg
aaaggttacaatccagcagaagtaggagctgctggcaagggctacctctggaaagctgca
ggcatgaacatggaggaagaggaggaactgcagcagaatctgtggggactcaagatcaac
atggaagaagagagtgaaagtgaaagtgagcaaagtatggattctgaggagccggacagc
cggggaggctcccctcagatggatgacatcaaagtgttccagaatgaagttttaggaaca
ctacagcggggcaaagaggagaacatttcttgtgacaatctcgtcctggaaatcaactct
ctcaagtatgcctataacataagtctaaaggaggtgatgcaggtactgagccacgtggtc
ctggagttccccctgcaacagatggattccccgcttgactcaagccgctactgtgccctg
ctgcttcctctgctaaaggcctggagccctgtttttaggaactacataaagcgcgcagcc
gaccatttggaagcgttagcagccattgaggacttcttcctagagcatgaagctcttggt
atttccatggccaaggtactgatggctttctaccagctggagatcctggctgaggaaaca
attctgagctggttcagccaaagagatacaactgacaagggccagcagttgcgcaagaat
caacagctgcagaggttcatccagtggctaaaagaggcagaagaggagtcatctgaagat
gactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (4)   
   KEGG NETWORK (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (29)   
   RefSeq(nuc) (7)   
   GenBank (11)   
   EMBL (11)   
3D Structure (21)   
   PDB (21)   
Protein domain (5)   
   Pfam (5)   
All databases (98)   

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