KEGG   Homo sapiens (human): 8975
Entry
8975              CDS       T01001                                 

Symbol
USP13, ISOT3, IsoT-3
Name
(RefSeq) ubiquitin specific peptidase 13
  KO
K11836  ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    8975 (USP13)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    8975 (USP13)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    8975 (USP13)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     8975 (USP13)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   8975 (USP13)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    8975 (USP13)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   8975 (USP13)
SSDB
Motif
Pfam: UCH zf-UBP_var UBA zf-UBP UCH_1 UBA_4 UBA_3
Other DBs
NCBI-GeneID: 8975
NCBI-ProteinID: NP_003931
OMIM: 603591
HGNC: 12611
Ensembl: ENSG00000058056
Vega: OTTHUMG00000157783
Pharos: Q92995(Tchem)
UniProt: Q92995 A0A0A6YZ17
Structure
Position
3:179653040..179789401
AA seq 863 aa
MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG
GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL
DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD
TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG
GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG
TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF
QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ
QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER
IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP
FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD
VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ
LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG
ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM
ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH
KVCASERPPKDLGYMYFYRRIPS
NT seq 2592 nt   +upstreamnt  +downstreamnt
atgcagcgccggggcgccctgttcggcatgccgggcggcagcggaggcaggaagatggct
gcaggagacatcggcgagctgctagtgccccacatgcccacgatccgcgtgcccaggtcc
ggcgacagggtctacaagaacgagtgcgccttctcctacgactctcccaattctgaaggt
ggactctatgtatgcatgaatacatttttggcctttggaagggaacatgttgaaagacat
tttcgaaaaactggacagagtgtatacatgcacctgaaaagacatgtgcgagagaaggta
agaggggcgtctggtggagcgttaccaaaaaggaggaattccaagatttttttagatcta
gatactgatgacgatttaaatagcgacgattatgaatatgaagatgaagccaaacttgtt
atattcccagatcactatgaaatagcactaccaaatattgaggagttaccagccctggta
acaattgcttgtgatgcagttctcagctcaaaatctccatacagaaagcaggacccagac
acgtgggaaaatgaattgccagtatctaaatatgccaacaacctcacccagctggacaat
ggagtcaggattcctccaagtggttggaagtgtgccagatgcgacctgcgagaaaacctc
tggttgaatctgactgacggctctgtcctgtgtggaaagtggttctttgacagctctggg
ggcaacgggcatgcgctggagcattacagagacatgggctacccactagccgtgaaactg
ggaaccatcactcctgacggggcagatgtttattcttttcaagaagaagaacctgttttg
gatcctcatttggccaagcacttagcgcattttggaattgatatgcttcatatgcatggg
acagagaatgggctccaggacaatgacatcaagctgagggtcagtgagtgggaagtgatc
caggagtcgggcacgaaactgaagccaatgtatggtcctggctacacgggtctgaagaac
ctgggcaacagctgctatctcagctctgtcatgcaggccatcttcagcatcccagaattc
cagagagcgtatgtaggaaaccttcccagaatatttgactactcgcctttagatccaaca
caagatttcaacacacagatgactaagttaggacatggccttctctcaggccagtattca
aagcctccggtgaaatctgaactcattgaacaggtgatgaaggaggagcacaagccacag
cagaacgggatctctccgcgcatgtttaaggcctttgtaagcaagagccacccggaattc
tcctctaacaggcagcaagatgcccaggaattcttcttgcacctggtgaatctagtagag
aggaaccgcatcggctcagaaaacccaagcgatgtttttcgttttttggtggaagaacgc
attcagtgctgtcagacccggaaagtccgctacacggagagggtggattacctgatgcag
ttacctgtggccatggaggcggcaaccaacaaggatgaactgatcgcttatgaactaacg
agaagggaagcagaagcaaacagaagaccccttcctgagttggtacgtgccaagatacca
tttagtgcctgccttcaggccttctctgaaccagaaaatgttgatgatttctggagcagt
gccctacaagcaaagtctgcgggtgtgaaaacatctcgctttgcttcattccctgaatac
ttggtagtgcagataaagaagttcacttttggtcttgactgggttcccaaaaaatttgat
gtttctattgatatgccagacctacttgatatcaaccatctccgagccagggggttacag
ccaggagaggaagaacttccagacatcagcccccccatagtcattcctgatgactcaaaa
gatcgcctgatgaaccaattgatagacccatcagacatcgatgagtcatcagtgatgcag
ctggccgagatgggtttcccgctggaagcatgtcgcaaggctgtgtacttcactggaaat
atgggcgccgaggtggccttcaactggatcattgttcacatggaagagccagattttgct
gagccgctgaccatgcctggttatggaggggcagcttctgctggagcctctgtttttggt
gcttctggactggataaccaacctccagaggaaatcgtagctatcatcacctccatggga
tttcagcgaaatcaggctattcaggcactacgagcaacgaataataacctggaaagagca
ctggattggatctttagccaccctgagtttgaagaagacagtgattttgtgattgagatg
gagaataatgccaatgcaaacattatttctgaggccaagcccgaaggacctagagtcaag
gatggatctggaacatatgagctatttgcattcatcagtcacatgggaacatccacaatg
agtggtcattacatttgccatatcaaaaaggaaggaagatgggtgatttacaatgaccac
aaagtttgtgcctcagaaaggccccctaaagacctgggctacatgtacttttaccgcagg
ataccaagctaa

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