| Entry |
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| Gene name |
MAP3K14, FTDCR1B, HS, HSNIK, NIK
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| Definition |
(RefSeq) mitogen-activated protein kinase kinase kinase 14
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| KO |
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| Organism |
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| Pathway |
| hsa04625 | C-type lectin receptor signaling pathway |
| hsa04660 | T cell receptor signaling pathway |
| hsa04672 | Intestinal immune network for IgA production |
| hsa05120 | Epithelial cell signaling in Helicobacter pylori infection |
| hsa05166 | Human T-cell leukemia virus 1 infection |
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| Network |
nt06123 TNF signaling (viruses and bacteria) nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06223 TNF signaling |
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| Element |
| N00505 | CD40-NFKB signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
9020 (MAP3K14)
04064 NF-kappa B signaling pathway
9020 (MAP3K14)
04668 TNF signaling pathway
9020 (MAP3K14)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
9020 (MAP3K14)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
9020 (MAP3K14)
04660 T cell receptor signaling pathway
9020 (MAP3K14)
04672 Intestinal immune network for IgA production
9020 (MAP3K14)
09158 Development and regeneration
04380 Osteoclast differentiation
9020 (MAP3K14)
09160 Human Diseases
09171 Infectious disease: bacterial
05120 Epithelial cell signaling in Helicobacter pylori infection
9020 (MAP3K14)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
9020 (MAP3K14)
05169 Epstein-Barr virus infection
9020 (MAP3K14)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
9020 (MAP3K14)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
9020 (MAP3K14)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: STE group
Other
9020 (MAP3K14)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
17q21.31
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| AA seq |
947 aa
MAVMEMACPGAPGSAVGQQKELPKAKEKTPPLGKKQSSVYKLEAVEKSPVFCGKWEILND
VITKGTAKEGSEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNN
VAHATEGKMARVCWKGKRRSKARKKRKKKSSKSLAHAGVALAKPLPRTPEQESCTIPVQE
DESPLGAPYVRNTPQFTKPLKEPGLGQLCFKQLGEGLRPALPRSELHKLISPLQCLNHVW
KLHHPQDGGPLPLPTHPFPYSRLPHPFPFHPLQPWKPHPLESFLGKLACVDSQKPLPDPH
LSKLACVDSPKPLPGPHLEPSCLSRGAHEKFSVEEYLVHALQGSVSSGQAHSLTSLAKTW
AARGSRSREPSPKTEDNEGVLLTEKLKPVDYEYREEVHWATHQLRLGRGSFGEVHRMEDK
QTGFQCAVKKVRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGGSLGQL
VKEQGCLPEDRALYYLGQALEGLEYLHSRRILHGDVKADNVLLSSDGSHAALCDFGHAVC
LQPDGLGKSLLTGDYIPGTETHMAPEVVLGRSCDAKVDVWSSCCMMLHMLNGCHPWTQFF
RGPLCLKIASEPPPVREIPPSCAPLTAQAIQEGLRKEPIHRVSAAELGGKVNRALQQVGG
LKSPWRGEYKEPRHPPPNQANYHQTLHAQPRELSPRAPGPRPAEETTGRAPKLQPPLPPE
PPEPNKSPPLTLSKEESGMWEPLPLSSLEPAPARNPSSPERKATVPEQELQQLEIELFLN
SLSQPFSLEEQEQILSCLSIDSLSLSDDSEKNPSKASQSSRDTLSSGVHSWSSQAEARSS
SWNMVLARGRPTDTPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPAAAFS
LVTKDGQPVRYDMEVPDSGIDLQCTLAPDGSFAWSWRVKHGQLENRP |
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| NT seq |
2844 nt +upstreamnt +downstreamnt
atggcagtgatggaaatggcctgcccaggtgcccctggctcagcagtggggcagcagaag
gaactccccaaagccaaggagaagacgccgccactggggaagaaacagagctccgtctac
aagcttgaggccgtggagaagagccctgtgttctgcggaaagtgggagatcctgaatgac
gtgattaccaagggcacagccaaggaaggctccgaggcagggccagctgccatctctatc
atcgcccaggctgagtgtgagaatagccaagagttcagccccaccttttcagaacgcatt
ttcatcgctgggtccaaacagtacagccagtccgagagtcttgatcagatccccaacaat
gtggcccatgctacagagggcaaaatggcccgtgtgtgttggaagggaaagcgtcgcagc
aaagcccggaagaaacggaagaagaagagctcaaagtccctggctcatgcaggagtggcc
ttggccaaacccctccccaggacccctgagcaggagagctgcaccatcccagtgcaggag
gatgagtctccactcggcgccccatatgttagaaacaccccgcagttcaccaagcctctg
aaggaaccaggccttgggcaactctgttttaagcagcttggcgagggcctacggccggct
ctgcctcgatcagaactccacaaactgatcagccccttgcaatgtctgaaccacgtgtgg
aaactgcaccacccccaggacggaggccccctgcccctgcccacgcaccccttcccctat
agcagactgcctcatcccttcccattccaccctctccagccctggaaacctcaccctctg
gagtccttcctgggcaaactggcctgtgtagacagccagaaacccttgcctgacccacac
ctgagcaaactggcctgtgtagacagtccaaagcccctgcctggcccacacctggagccc
agctgcctgtctcgtggtgcccatgagaagttttctgtggaggaatacctagtgcatgct
ctgcaaggcagcgtgagctcaggccaggcccacagcctgaccagcctggccaagacctgg
gcagcaaggggctccagatcccgggagcccagccccaaaactgaggacaacgagggtgtc
ctgctcactgagaaactcaagccagtggattatgagtaccgagaagaagtccactgggcc
acgcaccagctccgcctgggcagaggctccttcggagaggtgcacaggatggaggacaag
cagactggcttccagtgcgctgtcaaaaaggtgcggctggaagtatttcgggcagaggag
ctgatggcatgtgcaggattgacctcacccagaattgtccctttgtatggagctgtgaga
gaagggccttgggtcaacatcttcatggagctgctggaaggtggctccctgggccagctg
gtcaaggagcagggctgtctcccagaggaccgggccctgtactacctgggccaggccctg
gagggtctggaatacctccactcacgaaggattctgcatggggacgtcaaagctgacaac
gtgctcctgtccagcgatgggagccacgcagccctctgtgactttggccatgctgtgtgt
cttcaacctgatggcctgggaaagtccttgctcacaggggactacatccctggcacagag
acccacatggctccggaggtggtgctgggcaggagctgcgacgccaaggtggatgtctgg
agcagctgctgtatgatgctgcacatgctcaacggctgccacccctggactcagttcttc
cgagggccgctctgcctcaagattgccagcgagcctccgcctgtgagggagatcccaccc
tcctgcgcccctctcacagcccaggccatccaagaggggctgaggaaagagcccatccac
cgcgtgtctgcagcggagctgggagggaaggtgaaccgggcactacagcaagtgggaggt
ctgaagagcccttggaggggagaatataaagaaccaagacatccaccgccaaatcaagcc
aattaccaccagaccctccatgcccagccgagagagctttcgccaagggccccagggccc
cggccagctgaggagacaacaggcagagcccctaagctccagcctcctctcccaccagag
cccccagagccaaacaagtctcctcccttgactttgagcaaggaggagtctgggatgtgg
gaacccttacctctgtcctccctggagccagcccctgccagaaaccccagctcaccagag
cggaaagcaaccgtcccggagcaggaactgcagcagctggaaatagaattattcctcaac
agcctgtcccagccattttctctggaggagcaggagcaaattctctcgtgcctcagcatc
gacagcctctccctgtcggatgacagtgagaagaacccatcaaaggcctctcaaagctcg
cgggacaccctgagctcaggcgtacactcctggagcagccaggccgaggctcgaagctcc
agctggaacatggtgctggcccgggggcggcccaccgacaccccaagctatttcaatggt
gtgaaagtccaaatacagtctcttaatggtgaacacctgcacatccgggagttccaccgg
gtcaaagtgggagacatcgccactggcatcagcagccagatcccagctgcagccttcagc
ttggtcaccaaagacgggcagcctgttcgctacgacatggaggtgccagactcgggcatc
gacctgcagtgcacactggcccctgatggcagcttcgcctggagctggagggtcaagcat
ggccagctggagaacaggccctaa |
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