KEGG   Homo sapiens (human): 9064
Entry
9064              CDS       T01001                                 
Symbol
MAP3K6, ASK2, MAPKKK6, MEKK6
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 6
  KO
K04425  mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    9064 (MAP3K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9064 (MAP3K6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     9064 (MAP3K6)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE11 family
   9064 (MAP3K6)
SSDB
Motif
Pfam: MAP3K_TRAF_bd Pkinase PK_Tyr_Ser-Thr HisK-N-like TPR-S ASK_PH DRHyd-ASK YrbL-PhoP_reg Pkinase_fungal
Other DBs
NCBI-GeneID: 9064
NCBI-ProteinID: NP_004663
OMIM: 604468
HGNC: 6858
Ensembl: ENSG00000142733
UniProt: O95382
Position
1:complement(27355184..27366961)
AA seq 1288 aa
MAGPCPRSGAERAGSCWQDPLAVALSRGRQLAAPPGRGCARSRPLSVVYVLTREPQPGLE
PREGTEAEPLPLRCLREACAQVPRPRPPPQLRSLPFGTLELGDTAALDAFYNADVVVLEV
SSSLVQPSLFYHLGVRESFSMTNNVLLCSQADLPDLQALREDVFQKNSDCVGSYTLIPYV
VTATGRVLCGDAGLLRGLADGLVQAGVGTEALLTPLVGRLARLLEATPTDSCGYFRETIR
RDIRQARERFSGPQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETL
QALPTCDVAEQHNVCFHYTFALNRRNRPGDRAKALSVLLPLVQLEGSVAPDLYCMCGRIY
KDMFFSSGFQDAGHREQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSKELRLIGM
KLGCLLARKGCVEKMQYYWDVGFYLGAQILANDPTQVVLAAEQLYKLNAPIWYLVSVMET
FLLYQHFRPTPEPPGGPPRRAHFWLHFLLQSCQPFKTACAQGDQCLVLVLEMNKVLLPAK
LEVRGTDPVSTVTLSLLEPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQ
LCFPSVGHCQWFCGLIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYG
VVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKI
FMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLIN
TFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVI
EMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQAFLLRTFEPDPRLRASAQTL
LGDPFLQPGKRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHPPSPPK
RCLSYGGTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLH
QEQKQEQGARLGRNHVEELLRCLGAHIHTPNRRQLAQELRALQGRLRAQGLGPALLHRPL
FAFPDAVKQILRKRQIRPHWMFVLDSLLSRAVRAALGVLGPEVEKEAVSPRSEELSNEGD
SQQSPGQQSPLPVEPEQGPAPLMVQLSLLRAETDRLREILAGKEREYQALVQRALQRLNE
EARTYVLAPEPPTALSTDQGLVQWLQELNVDSGTIQMLLNHSFTLHTLLTYATRDDLIYT
RIRGGMVCRIWRAILAQRAGSTPVTSGP
NT seq 3867 nt   +upstreamnt  +downstreamnt
atggcggggccgtgtccccggtccggggcggagcgcgccggcagctgctggcaggacccg
ctggccgtggcgctgagccggggccggcagctcgcggcgcccccgggccggggctgcgcg
cggagccggccgctcagcgtggtctacgtgctgacccgggagccgcagcccgggctcgag
cctcgggagggaaccgaggcggagccgctgcccctgcgctgcctgcgcgaggcttgcgcg
caggtcccccggccgcggccgcccccgcagctgcgcagcctgcccttcgggacgctggag
ctaggcgacaccgcggctctggatgccttctacaacgcggatgtggtggtgctggaggtg
agcagctcgctggtacagccctccctgttctaccaccttggtgtgcgtgagagcttcagc
atgaccaacaatgtgctcctctgctcccaggccgacctccctgacctgcaggccctgcgg
gaggatgttttccagaagaactcggattgcgttggcagctacacactgatcccctatgtg
gtgacggccactggtcgggtgctgtgtggtgatgcaggccttctgcggggcctggctgat
gggctggtacaggctggagtggggaccgaggccctgctcactcccctggtgggccggctt
gcccgcctgctggaggccacacccacagactcttgtggctatttccgggagaccattcgg
cgggacatccggcaggcgcgggagcggttcagtgggccacagctgcggcaggagctggct
cgcctgcagcggagactggacagcgtggagctgctgagccccgacatcatcatgaacttg
ctgctctcctaccgcgatgtgcaggactactcggccatcattgagctggtggagacgctg
caggccttgcccacctgtgatgtggccgagcagcataatgtctgcttccactacactttt
gccctcaaccggaggaacaggcctggggaccgggcgaaggccctgtctgtgctgctgccg
ctggtacagcttgagggctctgtggcgcccgatctgtactgcatgtgtggccgtatctac
aaggacatgttcttcagctcgggtttccaggatgctgggcaccgggagcaggcctatcac
tggtatcgcaaggcttttgacgtagagcccagccttcactcaggcatcaatgcagctgtg
ctcctcattgctgccgggcagcactttgaggattccaaagagctccggctaataggcatg
aagctgggctgcctgctggcccgcaaaggctgcgtggagaagatgcagtattactgggat
gtgggtttctacctgggagcccagatcctcgccaatgaccccacccaggtggtgctggct
gcagagcagctgtataagctcaatgcccccatatggtacctggtgtccgtgatggagacc
ttcctgctctaccagcacttcaggcccacgccagagccccctggagggccaccacgccgt
gcccacttctggctccacttcttgctacagtcctgccaaccattcaagacagcctgtgcc
cagggcgaccagtgcttggtgctggtcctggagatgaacaaggtgctgctgcctgcaaag
ctcgaggttcggggtactgacccagtaagcacagtgaccctgagcctgctggagcctgag
acccaggacattccctccagctggaccttcccagtcgcctccatatgcggagtcagcgcc
tcaaagcgcgacgagcgctgctgcttcctctatgcactccccccggctcaggacgtccag
ctgtgcttccccagcgtagggcactgccagtggttctgcggcctgatccaggcctgggtg
acgaacccggattccacggcgcccgcggaggaggcggagggcgcgggggagatgttggag
tttgattatgagtacacggagacgggcgagcggctggtgctgggcaagggcacgtatggg
gtggtgtacgcgggccgcgatcgccacacgagggtgcgcatcgccatcaaggagatcccg
gagcgggacagcaggttctctcagcccctgcatgaagagatcgctcttcacagacgcctg
cgccacaagaacatagtgcgctatctgggctcagctagccagggcggctaccttaagatc
ttcatggaggaagtgcctggaggcagcctgtcctccttgctgcggtcggtgtggggaccc
ctgaaggacaacgagagcaccatcagtttctacacccgccagatcctgcagggacttggc
tacttgcacgacaaccacatcgtgcacagggacataaaaggggacaatgtgctgatcaac
accttcagtgggctgctcaagatttctgacttcggcacctccaagcggctggcaggcatc
acaccttgcactgagaccttcacaggaactctgcagtatatggccccagaaatcattgac
cagggcccacgcgggtatgggaaagcagctgacatctggtcactgggctgcactgtcatt
gagatggccacaggtcgcccccccttccacgagctcgggagcccacaggctgccatgttt
caggtgggtatgtacaaggtccatccgccaatgcccagctctctgtcggccgaggcccaa
gcctttctcctccgaacttttgagccagacccccgcctccgagccagcgcccagacactg
ctgggggaccccttcctgcagcctgggaaaaggagccgcagccccagctccccacgacat
gctccacggccctcagatgccccttctgccagtcccactccttcagccaactcaaccacc
cagtctcagacattcccgtgccctcaggcaccctctcagcacccacccagccccccgaag
cgctgcctcagttatgggggcaccagccagctccgggtgcccgaggagcctgcggccgag
gagcctgcgtctccggaggagagttcggggctgagcctgctgcaccaggagagcaagcgt
cgggccatgctggccgcagtattggagcaggagctgccagcgctggcggagaatctgcac
caggagcagaagcaagagcagggggcccgtctgggcagaaaccatgtggaagagctgctg
cgctgcctcggggcacacatccacactcccaaccgccggcagctcgcccaggagctgcgg
gcgctgcaaggacggctgagggcccagggccttgggcctgcgcttctgcacagaccgctg
tttgccttcccggatgcggtgaagcagatcctccgcaagcgccagatccgtccacactgg
atgttcgttctggactcactgctcagccgtgctgtgcgggcagccctgggtgtgctagga
ccggaggtggagaaggaggcggtctcaccgaggtcagaggagctgagtaatgaaggggac
tcccagcagagcccaggccagcagagcccgcttccggtggagcccgagcagggccccgct
cctctgatggtgcagctgagcctcttgagggcagagactgatcggctgcgcgaaatcctg
gcggggaaggaacgggagtaccaggccctggtgcagcgggctctacagcggctgaatgag
gaagcccggacctatgtcctggccccagagcctccaactgctctttcaacggaccagggc
ctggtgcagtggctacaggaactgaatgtggattcaggcaccatccaaatgctgttgaac
catagcttcaccctccacactctgctcacctatgccactcgagatgacctcatctacacc
cgcatcaggggagggatggtatgccgcatctggagggccatcttggcacagcgagcagga
tccacaccagtcacctctggaccctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (28)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (33)   
   RefSeq(nuc) (11)   
   GenBank (11)   
   EMBL (11)   
Protein domain (9)   
   Pfam (9)   
All databases (83)   

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