KEGG   Homo sapiens (human): 9064Help
Entry
9064              CDS       T01001                                 

Gene name
MAP3K6, ASK2, MAPKKK6, MEKK6
Definition
(RefSeq) mitogen-activated protein kinase kinase kinase 6
  KO
K04425  mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Module
hsa_M00688  MAPK (JNK) signaling
hsa_M00689  MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    9064 (MAP3K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9064 (MAP3K6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     9064 (MAP3K6)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE11 family
   9064 (MAP3K6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DUF4071 Pkinase Pkinase_Tyr Pkinase_fungal SAM_KSR1
Motif
Other DBs
NCBI-GeneID: 9064
NCBI-ProteinID: NP_004663
OMIM: 604468
HGNC: 6858
Ensembl: ENSG00000142733
Vega: OTTHUMG00000004631
Pharos: O95382(Tbio)
UniProt: O95382
Position
1p36.11
AA seq 1288 aa AA seqDB search
MAGPCPRSGAERAGSCWQDPLAVALSRGRQLAAPPGRGCARSRPLSVVYVLTREPQPGLE
PREGTEAEPLPLRCLREACAQVPRPRPPPQLRSLPFGTLELGDTAALDAFYNADVVVLEV
SSSLVQPSLFYHLGVRESFSMTNNVLLCSQADLPDLQALREDVFQKNSDCVGSYTLIPYV
VTATGRVLCGDAGLLRGLADGLVQAGVGTEALLTPLVGRLARLLEATPTDSCGYFRETIR
RDIRQARERFSGPQLRQELARLQRRLDSVELLSPDIIMNLLLSYRDVQDYSAIIELVETL
QALPTCDVAEQHNVCFHYTFALNRRNRPGDRAKALSVLLPLVQLEGSVAPDLYCMCGRIY
KDMFFSSGFQDAGHREQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSKELRLIGM
KLGCLLARKGCVEKMQYYWDVGFYLGAQILANDPTQVVLAAEQLYKLNAPIWYLVSVMET
FLLYQHFRPTPEPPGGPPRRAHFWLHFLLQSCQPFKTACAQGDQCLVLVLEMNKVLLPAK
LEVRGTDPVSTVTLSLLEPETQDIPSSWTFPVASICGVSASKRDERCCFLYALPPAQDVQ
LCFPSVGHCQWFCGLIQAWVTNPDSTAPAEEAEGAGEMLEFDYEYTETGERLVLGKGTYG
VVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKI
FMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLIN
TFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVI
EMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEAQAFLLRTFEPDPRLRASAQTL
LGDPFLQPGKRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHPPSPPK
RCLSYGGTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLH
QEQKQEQGARLGRNHVEELLRCLGAHIHTPNRRQLAQELRALQGRLRAQGLGPALLHRPL
FAFPDAVKQILRKRQIRPHWMFVLDSLLSRAVRAALGVLGPEVEKEAVSPRSEELSNEGD
SQQSPGQQSPLPVEPEQGPAPLMVQLSLLRAETDRLREILAGKEREYQALVQRALQRLNE
EARTYVLAPEPPTALSTDQGLVQWLQELNVDSGTIQMLLNHSFTLHTLLTYATRDDLIYT
RIRGGMVCRIWRAILAQRAGSTPVTSGP
NT seq 3867 nt NT seq  +upstreamnt  +downstreamnt
atggcggggccgtgtccccggtccggggcggagcgcgccggcagctgctggcaggacccg
ctggccgtggcgctgagccggggccggcagctcgcggcgcccccgggccggggctgcgcg
cggagccggccgctcagcgtggtctacgtgctgacccgggagccgcagcccgggctcgag
cctcgggagggaaccgaggcggagccgctgcccctgcgctgcctgcgcgaggcttgcgcg
caggtcccccggccgcggccgcccccgcagctgcgcagcctgcccttcgggacgctggag
ctaggcgacaccgcggctctggatgccttctacaacgcggatgtggtggtgctggaggtg
agcagctcgctggtacagccctccctgttctaccaccttggtgtgcgtgagagcttcagc
atgaccaacaatgtgctcctctgctcccaggccgacctccctgacctgcaggccctgcgg
gaggatgttttccagaagaactcggattgcgttggcagctacacactgatcccctatgtg
gtgacggccactggtcgggtgctgtgtggtgatgcaggccttctgcggggcctggctgat
gggctggtacaggctggagtggggaccgaggccctgctcactcccctggtgggccggctt
gcccgcctgctggaggccacacccacagactcttgtggctatttccgggagaccattcgg
cgggacatccggcaggcgcgggagcggttcagtgggccacagctgcggcaggagctggct
cgcctgcagcggagactggacagcgtggagctgctgagccccgacatcatcatgaacttg
ctgctctcctaccgcgatgtgcaggactactcggccatcattgagctggtggagacgctg
caggccttgcccacctgtgatgtggccgagcagcataatgtctgcttccactacactttt
gccctcaaccggaggaacaggcctggggaccgggcgaaggccctgtctgtgctgctgccg
ctggtacagcttgagggctctgtggcgcccgatctgtactgcatgtgtggccgtatctac
aaggacatgttcttcagctcgggtttccaggatgctgggcaccgggagcaggcctatcac
tggtatcgcaaggcttttgacgtagagcccagccttcactcaggcatcaatgcagctgtg
ctcctcattgctgccgggcagcactttgaggattccaaagagctccggctaataggcatg
aagctgggctgcctgctggcccgcaaaggctgcgtggagaagatgcagtattactgggat
gtgggtttctacctgggagcccagatcctcgccaatgaccccacccaggtggtgctggct
gcagagcagctgtataagctcaatgcccccatatggtacctggtgtccgtgatggagacc
ttcctgctctaccagcacttcaggcccacgccagagccccctggagggccaccacgccgt
gcccacttctggctccacttcttgctacagtcctgccaaccattcaagacagcctgtgcc
cagggcgaccagtgcttggtgctggtcctggagatgaacaaggtgctgctgcctgcaaag
ctcgaggttcggggtactgacccagtaagcacagtgaccctgagcctgctggagcctgag
acccaggacattccctccagctggaccttcccagtcgcctccatatgcggagtcagcgcc
tcaaagcgcgacgagcgctgctgcttcctctatgcactccccccggctcaggacgtccag
ctgtgcttccccagcgtagggcactgccagtggttctgcggcctgatccaggcctgggtg
acgaacccggattccacggcgcccgcggaggaggcggagggcgcgggggagatgttggag
tttgattatgagtacacggagacgggcgagcggctggtgctgggcaagggcacgtatggg
gtggtgtacgcgggccgcgatcgccacacgagggtgcgcatcgccatcaaggagatcccg
gagcgggacagcaggttctctcagcccctgcatgaagagatcgctcttcacagacgcctg
cgccacaagaacatagtgcgctatctgggctcagctagccagggcggctaccttaagatc
ttcatggaggaagtgcctggaggcagcctgtcctccttgctgcggtcggtgtggggaccc
ctgaaggacaacgagagcaccatcagtttctacacccgccagatcctgcagggacttggc
tacttgcacgacaaccacatcgtgcacagggacataaaaggggacaatgtgctgatcaac
accttcagtgggctgctcaagatttctgacttcggcacctccaagcggctggcaggcatc
acaccttgcactgagaccttcacaggaactctgcagtatatggccccagaaatcattgac
cagggcccacgcgggtatgggaaagcagctgacatctggtcactgggctgcactgtcatt
gagatggccacaggtcgcccccccttccacgagctcgggagcccacaggctgccatgttt
caggtgggtatgtacaaggtccatccgccaatgcccagctctctgtcggccgaggcccaa
gcctttctcctccgaacttttgagccagacccccgcctccgagccagcgcccagacactg
ctgggggaccccttcctgcagcctgggaaaaggagccgcagccccagctccccacgacat
gctccacggccctcagatgccccttctgccagtcccactccttcagccaactcaaccacc
cagtctcagacattcccgtgccctcaggcaccctctcagcacccacccagccccccgaag
cgctgcctcagttatgggggcaccagccagctccgggtgcccgaggagcctgcggccgag
gagcctgcgtctccggaggagagttcggggctgagcctgctgcaccaggagagcaagcgt
cgggccatgctggccgcagtattggagcaggagctgccagcgctggcggagaatctgcac
caggagcagaagcaagagcagggggcccgtctgggcagaaaccatgtggaagagctgctg
cgctgcctcggggcacacatccacactcccaaccgccggcagctcgcccaggagctgcgg
gcgctgcaaggacggctgagggcccagggccttgggcctgcgcttctgcacagaccgctg
tttgccttcccggatgcggtgaagcagatcctccgcaagcgccagatccgtccacactgg
atgttcgttctggactcactgctcagccgtgctgtgcgggcagccctgggtgtgctagga
ccggaggtggagaaggaggcggtctcaccgaggtcagaggagctgagtaatgaaggggac
tcccagcagagcccaggccagcagagcccgcttccggtggagcccgagcagggccccgct
cctctgatggtgcagctgagcctcttgagggcagagactgatcggctgcgcgaaatcctg
gcggggaaggaacgggagtaccaggccctggtgcagcgggctctacagcggctgaatgag
gaagcccggacctatgtcctggccccagagcctccaactgctctttcaacggaccagggc
ctggtgcagtggctacaggaactgaatgtggattcaggcaccatccaaatgctgttgaac
catagcttcaccctccacactctgctcacctatgccactcgagatgacctcatctacacc
cgcatcaggggagggatggtatgccgcatctggagggccatcttggcacagcgagcagga
tccacaccagtcacctctggaccctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (1)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (28)   
   RefSeq(nuc) (6)   
   GenBank (11)   
   EMBL (11)   
Protein domain (5)   
   Pfam (5)   
All databases (80)   

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