KEGG   Homo sapiens (human): 9098
Entry
9098              CDS       T01001                                 
Symbol
USP6, HRP1, TRE17, TRE2, TRESMCR, Tre-2, USP6-short
Name
(RefSeq) ubiquitin specific peptidase 6
  KO
K11837  ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    9098 (USP6)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    9098 (USP6)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     9098 (USP6)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   9098 (USP6)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    9098 (USP6)
SSDB
Motif
Pfam: UCH RabGAP-TBC RabGap-TBC_2 UCH_1
Other DBs
NCBI-GeneID: 9098
NCBI-ProteinID: NP_001291213
OMIM: 604334
HGNC: 12629
Ensembl: ENSG00000129204
UniProt: P35125
Position
17:5116032..5174991
AA seq 1406 aa
MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVT
AREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIK
LKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYN
PEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH
VVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT
SIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPA
KREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAV
REDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVR
AISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNT
CFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSV
APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWE
VAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE
ITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNIKNFPQDNQ
KVQLSVSGFLCAFEIPVPSSPISASSPTQIDFSSSPSTNGMFTLTTNGDLPKPIFIPNGM
PNTVVPCGTEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFG
MPLIVPCTVHTRKKDLYDAVWIQVSWLARPLPPQEASIHAQDRDNCMGYQYPFTLRVVQK
DGNSCAWCPQYRFCRGCKIDCGEDRAFIGNAYIAVDWHPTALHLRYQTSQERVVDKHESV
EQSRRAQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHL
KRFQFVNDQWIKSQKIVRFLRESFDPSAFLVPRDPALCQHKPLTPQGDELSKPRILAREV
KKVDAQSSAGKEDMLLSKSPSSLSANISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTL
GRSKGRLRLPQIGSKNKPSSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQ
DHEVALANGFLYEHEACGNGCGDGYSNGQLGNHSEEDSTDDQREDTHIKPIYNLYAISCH
SGILSGGHYITYAKNPNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQGIDYAQFLPKI
DGKKMADTSSTDEDSESDYEKYSMLQ
NT seq 4221 nt   +upstreamnt  +downstreamnt
atggacatggtagagaatgcagatagtttgcaggcacaggagcggaaggacatacttatg
aagtatgacaagggacaccgagctgggctgccagaggacaaggggcctgagcccgttgga
atcaacagcagcattgatcgttttggcattttgcatgagacggagctgcctcctgtgact
gcacgggaggcgaagaaaattcggcgggagatgacacgaacgagcaagtggatggaaatg
ctgggagaatgggagacatataagcacagtagcaaactcatagatcgagtgtacaaggga
attcccatgaacatccggggcccggtgtggtcagtcctcctgaacattcaggaaatcaag
ttgaaaaaccccggaagataccagatcatgaaggagaggggcaagaggtcatctgaacac
atccaccacatcgacctggacgtgaggacgactctccggaaccatgtcttctttagggat
cgatatggagccaagcagagggaactattctacatcctcctggcctattcggagtataac
ccggaggtgggctactgcagggacctgagccacatcaccgccttgttcctcctttatctg
cctgaggaggacgcattctgggcactggtgcagctgctggccagtgagaggcactccctg
ccaggattccacagcccaaatggtgggacagtccaggggctccaagaccaacaggagcat
gtggtacccaagtcacaacccaagaccatgtggcatcaggacaaggaaggtctatgcggg
cagtgtgcctcgttaggctgccttctccggaacctgattgacgggatctctctcgggctc
accctgcgcctgtgggacgtgtatttggtggaaggagaacaggtgttgatgccaataacc
agcattgctcttaaggttcagcagaagcgcctcatgaagacatccaggtgtggcctgtgg
gcacgtctgcggaaccaattcttcgatacctgggccatgaacgatgacaccgtgctcaag
catcttagggcctctacgaagaaactaacaaggaagcaaggggacctgccacccccagcc
aaacgcgagcaagggtccttggcacccaggcctgtgccggcttcacgtggtgggaagacc
ctctgcaaggggtataggcaggcccctccaggcccaccagcccagttccagcggcccatt
tgctcagcttccccgccatgggcatctcgtttttccacgccctgtcctggtggggctgtc
cgggaagacacgtaccctgtgggcactcagggtgtgcccagcctggccctggctcaggga
ggacctcagggttcctggagattcctggagtggaagtcaatgccccggctcccaacggac
ctggatatagggggcccttggttcccccattatgattttgaatggagctgctgggtccgt
gccatatcccaggaggaccagctggccacctgctggcaggctgaacactgcggagaggtt
cacaacaaagatatgagttggcctgaggagatgtcttttacagcaaatagtagtaaaata
gatagacaaaaggttcccacagaaaagggagccacaggtctaagcaacctgggaaacaca
tgcttcatgaactcaagcatccagtgcgttagtaacacacagccactgacacagtatttt
atctcagggagacatctttatgaactcaacaggacaaatcccattggtatgaaggggcat
atggctaaatgctatggtgatttagtgcaggaactctggagtggaactcagaagagtgtt
gccccattaaagcttcggcggaccatagcaaaatatgctcccaagtttgatgggtttcag
caacaagactcccaagaacttctggcttttctcttggatggtcttcatgaagatctcaac
cgagtccatgaaaagccatatgtggaactgaaggacagtgatggccgaccagactgggaa
gtagctgcagaggcctgggacaaccatctaagaagaaatagatcaattattgtggatttg
ttccatgggcagctaagatctcaagtcaaatgcaagacatgtgggcatataagtgtccga
tttgaccctttcaattttttgtctttgccactaccaatggacagttacatggacttagaa
ataacagtgattaagttagatggtactacccctgtacggtatggactaagactgaatatg
gatgaaaagtacacaggtttaaaaaaacagctgagggatctctgtggacttaattcagaa
caaatcctactagcagaagtacatgattccaacataaagaactttcctcaggataaccaa
aaagtacaactctcagtgagcggatttttgtgtgcatttgaaattcctgtcccttcatct
ccaatttcagcttctagtccaacacaaatagatttctcctcttcaccatctacaaatgga
atgttcaccctaactaccaatggggacctacccaaaccaatattcatccccaatggaatg
ccaaacactgttgtgccatgtggaactgagaagaacttcacaaatggaatggttaatggt
cacatgccatctcttcctgacagcccctttacaggttacatcattgcagtccaccgaaaa
atgatgaggacagaactgtatttcctgtcacctcaggagaatcgccccagcctctttgga
atgccattgattgttccatgcactgtgcatacccggaagaaagacctatatgatgcggtt
tggattcaagtatcctggttagcaagaccactcccacctcaggaagctagtattcatgcc
caggatcgtgataactgtatgggctatcaatatccattcactctacgagttgtgcagaaa
gatgggaactcctgtgcttggtgcccacagtatagattttgcagaggctgtaaaattgat
tgtggggaagacagagctttcattggaaatgcctatattgctgtggattggcaccccaca
gcccttcaccttcgctatcaaacatcccaggaaagggttgtagataagcatgagagtgtg
gagcagagtcggcgagcgcaagccgagcccatcaacctggacagctgtctccgtgctttc
accagtgaggaagagctaggggaaagtgagatgtactactgttccaagtgtaagacccac
tgcttagcaacaaagaagctggatctctggaggcttccacccttcctgattattcacctt
aagcgatttcaatttgtaaatgatcagtggataaaatcacagaaaattgtcagatttctt
cgggaaagttttgatccgagtgcttttttggtaccacgagacccggccctctgccagcat
aaaccactcacaccccagggggatgagctctccaagcccaggattctggcaagagaggtg
aagaaagtggatgcgcagagttcggctggaaaagaggacatgctcctaagcaaaagccca
tcctcactcagcgctaacatcagcagcagcccaaaaggttctccttcttcatcaagaaaa
agtggaaccagctgtccctccagcaaaaacagcagccctaatagcagcccacggactttg
gggaggagcaaagggaggctccggctgccccagattggcagcaaaaataagccgtcaagt
agtaagaagaacttggatgccagcaaagagaatggggctgggcagatctgtgagctggct
gacgccttgagccgagggcatatgcgggggggcagccaaccagagctggtcactcctcag
gaccatgaggtagctttggccaatggattcctttatgagcatgaagcatgtggcaatggc
tgtggcgatggctacagcaatggtcagcttggaaaccacagtgaagaagacagcactgat
gaccaaagagaagacactcatattaagcctatttataatctatatgcaatttcatgccat
tcaggaattctgagtgggggccattacatcacttatgccaaaaacccaaactgcaagtgg
tactgttataatgacagcagctgtgaggaacttcaccctgatgaaattgacaccgactct
gcctacattcttttctatgagcagcaggggatagactacgcacaatttctgccaaagatt
gatggcaaaaagatggcagacacaagcagtacggatgaagactctgagtctgattacgaa
aagtactctatgttacagtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (46)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (38)   
   RefSeq(nuc) (22)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (112)   

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